Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Rika Sudo"'
Autor:
Rika Sudo, Hideo Takamori, Toshiyuki Sato, Osamu Sugita, Yujiro Hayashi, Norio Suzuki, Akio Kishida, Ken-ichiro Hiwatari, Hiroshi Kikuchi, Mitsuru Akashi, Shinji Sakuma, Yoshiharu Minamitake
Publikováno v:
Journal of Dispersion Science and Technology. 24:623-632
The ability of nanoparticles having surface hydrophilic polymeric chains to enhance the oral absorption of human calcitonin was examined in rats. The oral relative bioavailability of calcitonin against its subcutaneous administration was 0.01% withou
Publikováno v:
International Journal of Pharmaceutics. 177:161-172
The mucoadhesion of polystyrene nanoparticles having surface hydrophilic polymeric chains in the gastrointestinal (GI) tract was investigated in rats. Radiolabeled nanoparticles were synthesized by adding hydrophobic 3-(trifluoromethyl)-3-(m-[125I]io
Autor:
Hiroshi Kikuchi, Masahiro Hayashi, Akio Kishida, Mitsuru Akashi, Norio Suzuki, Yoshimasa Ishida, Rika Sudo, Shinji Sakuma, Ken-ichiro Hiwatari
Publikováno v:
International Journal of Pharmaceutics. 159:181-189
The effect of polystyrene nanoparticles having surface hydrophilic polymeric chains on the stability of salmon calcitonin (sCT) in the presence of digestive enzymes was investigated in vitro. sCT was protected against pepsin- or trypsin-catalyzed deg
Publikováno v:
International journal of pharmaceutics. 239(1-2)
Nanoparticles having two kinds of surface hydrophilic polymeric chains were prepared by the free radical copolymerization between styrene and hydrophilic macromonomers terminating in vinylbenzyl groups. Their potential as carriers for oral peptide de
Autor:
Masahiro Hayashi, Mitsuru Akashi, Shinji Sakuma, Rika Sudo, Yoshimasa Ishida, Norio Suzuki, Hiroshi Kikuchi
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 81(3)
The behavior of nanoparticles having surface hydrophilic poly(N-isopropylacrylamide), poly(N-vinylacetamide), poly(vinylamine) or poly(methacrylic acid) chains in the intestine was examined. The permeability of salmon calcitonin (sCT) from the mucosa
Publikováno v:
Biologicalpharmaceutical bulletin. 23(7)
Apparent membrane permeation coefficients (Papp) of poorly water-soluble drugs such as indomethacin (IDM) and triamterene (TAT) were obtained by the chamber method using an isolated rat intestinal tissue after solubilization of the drugs by additives