Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Rika Ishikawa"'
Autor:
Yuchen Sun, Kosuke Saito, Atsuhito Ushiki, Mitsuhiro Abe, Yoshinobu Saito, Takeru Kashiwada, Yasushi Horimasu, Akihiko Gemma, Koichiro Tatsumi, Noboru Hattori, Kenji Tsushima, Kazuhisa Takemoto, Rika Ishikawa, Toshiko Momiyama, Shin-ichiro Matsuyama, Noriaki Arakawa, Hirotoshi Akane, Takeshi Toyoda, Kumiko Ogawa, Motonobu Sato, Kazuhiko Takamatsu, Kazuhiko Mori, Takayoshi Nishiya, Takashi Izumi, Yasuo Ohno, Yoshiro Saito, Masayuki Hanaoka
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-23 (2024)
Abstract Background Drug-induced interstitial lung disease (DILD) is a lung injury caused by various types of drugs and is a serious problem in both clinical practice and drug development. Clinical management of the condition would be improved if the
Externí odkaz:
https://doaj.org/article/1318948710974ad7a181c0d83d189e4d
Autor:
Kosuke Saito, Rika Ishikawa, Isao Kitamura, Kumiko Ogawa, Noriaki Arakawa, Yuchen Sun, Kazuo Imai, Takuya Maeda, Yoshiro Saito, Chihiro Hasegawa
Publikováno v:
Journal of Pharmacological Sciences, Vol 150, Iss 2, Pp 49-55 (2022)
The coronavirus disease 2019 (COVID-19) pandemic has been associated with high mortality worldwide. Owing to its complicated pathophysiology, diagnostic and prognostic biomarkers for effective patient management remain scarce. We analyzed kynurenine,
Externí odkaz:
https://doaj.org/article/1a72e057b07643b1ac22799639a56ac4
Publikováno v:
Biomolecules, Vol 13, Iss 6, p 1002 (2023)
ATSP-7041, a stapled α-helical peptide that inhibits murine double minute-2 (MDM2) and MDMX activities, is a promising modality targeting protein–protein interactions. As peptides of molecular weights over 1000 Da are not usually evaluated, data o
Externí odkaz:
https://doaj.org/article/33988dc476b147e79655a904e7c8f6ac
Autor:
Rika Ishikawa, Kosuke Saito, Hidehisa Tachiki, Ryoya Goda, Koji Arai, Hisao Shimizu, Tomohiro Andou, Kentaro Takahara, Hitoshi Uchiyama, Shin-ichiro Nitta, Masaaki Kakehi, Kozo Hayashi, Naohiro Katagiri, Keiko Kojima, Hisashi Fujita, Kazuhiro Tsuchinaga, Yoshiro Saito
Publikováno v:
Bioanalysis. 15:207-218
Background: Although the fit-for-purpose approach has been proposed for biomarker assay validation, practical data should be compiled to facilitate the predetermination of acceptance criteria. Methods: Immunoaffinity LC–MS was used to analyze gluca
Autor:
Tsuyoshi Matsumura, Kota Asahina, Mariko Yamaoka, Mitsuhiko Kawabata, Rika Ishikawa, Saki Yamauchi, Takahiro Suga, Shin-Ichiro Nitta, Akemi Nagao, Yoshiro Saito, Hitoshi Uchiyama, Keiko Nakai, Koji Arai, Ryoya Goda, Kosuke Saito, Hidehisa Tachiki
Publikováno v:
Bioanalysis. 13(20)
Aim: Although the fit-for-purpose approach has been proposed for validation procedures and acceptance criteria for biomarker assays, practical biomarker assays to facilitate clinical application and regulatory documents on biomarker assays remain lim
Publikováno v:
Journal of Materials Science. 44:976-984
Micro-Raman spectroscopy was applied for evaluating the stress distributions in the vicinity of the interface of the steel/epoxy bonded joint under tensile loading condition. Herein, single-walled carbon nanotubes (SWNTs) embedded in a polymer can be
Publikováno v:
Journal of Immunoassay and Immunochemistry. 29:181-196
Erythropoietin (EPO) is a growth factor, regulating the proliferation and differentiation of erythroid progenitor cells. In this study, we generated five monoclonal antibodies (mAbs) that reacted specifically with recombinant human EPO (rhEPO). Epito
Publikováno v:
Journal of Chromatography A. 1133:332-339
Total N-linked oligosaccharide profiling method for recombinant monoclonal antibody (rmAb) using capillary electrophoresis with laser-induced fluorescence detection (CE-LIF) and an approach for detailed structural analysis of N-linked oligosaccharide
Publikováno v:
The Journal of Biochemistry. 140:49-56
We have studied methanol-induced conformational changes in rmethuG-CSF at pH 2.5 by means of circular dichroism (CD), fluorescence and infrared (IR) spectroscopy, and 8-anilino-1-naphthalene sulfonic acid (ANS) binding. Methanol has little effect on
Publikováno v:
The Journal of Biochemistry. 139:41-49
This paper reports the effect of ionic strength on the process of thermal unfolding of recombinant methionyl human granulocyte-colony stimulating factor (rmethuG-CSF) at acid pH. We previously reported that the protein aggregates were formed at the h