Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Rika Goda"'
Autor:
Takeshi Onda, Hitomi Hayashi, Hiroko Mashiba, Iwao Nakamura, Akira Masuda, Daichi Nagai, Eiji Ichimura, Hirofumi Yokoyama, Rika Goda
Publikováno v:
International Journal of Nanomedicine
Iwao Nakamura, Eiji Ichimura, Rika Goda, Hitomi Hayashi, Hiroko Mashiba, Daichi Nagai, Hirofumi Yokoyama, Takeshi Onda, Akira Masuda Nanomedicine Group, Pharmaceutical Research Laboratories, Nippon Kayaku Co., Ltd., Tokyo, Japan Abstract: In our prev
Autor:
Takayuki Hirai, Tetsuya Hamaguchi, Taito Esaki, Hirofumi Mukai, Yoshihiro Nambu, Ken Kato, Rika Goda, Shouzou Ohsumi, Yasuo Hozomi, Yasuhiro Matsumura, Nobuaki Matsubara
Publikováno v:
Investigational New Drugs
Previous studies have established the rationale for NK105, a nanomicellar formulation of paclitaxel, administered every 3 weeks. The aim of this phase I study was to determine the recommended dose and pharmacokinetics of weekly administered NK105. NK
Autor:
Yasushi Matsuzaki, Mikio Doi, Eiji Ichimura, Kiyohiro Nishikawa, Arihiro Tomura, Daichi Nagai, Rika Goda
Publikováno v:
Journal of Gastroenterology. 41:231-239
Flutamide, a nonsteroidal antiandrogen used for treatment of prostate cancer, causes a temporary increase in transaminase and in some cases severe liver dysfunction. It is dominantly metabolized by cytochrome P450 (CYP) 1A2 into 2-hydroxyflutamide (O
Publikováno v:
Drug Metabolism and Pharmacokinetics. 13:229-236
Publikováno v:
Journal of the Mass Spectrometry Society of Japan. 45:367-375
Cytochrome P450 (Cyt. P450) is capable of metabolizing a wide range of endogenous and xenobiotic compounds. The metabolism of testosterone has been used to probe into Cyt. P450 isoenzyme activities of rat liver preparations in vitro. Then we studied
Autor:
Rika Goda, Kiyohiro Nishikawa, Kiyoshi Nagata, Yoshio Aizawa, Yuji Akiyama, Isao Ikemoto, Yasushi Yamazoe, Daichi Nagai
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 34(5)
Flutamide (2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-propanamide), a nonsteroidal antiandrogen, is used in the treatment of prostate cancer but is occasionally associated with hepatic dysfunction. In the present study, the metabolism of flutamid
Autor:
Iwao Nakamura, Eiji Ichimura, Rika Goda, Hitomi Hayashi, Hiroko Mashiba, Daichi Nagai, Hirofumi Yokoyama, Takeshi Onda, Akira Masuda
Publikováno v:
International Journal of Nanomedicine; Feb2017, Vol. 12, p1293-1304, 12p