Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Rik J Lories"'
Autor:
Ana Escribano-Núñez, Frederique M. F. Cornelis, Astrid De Roover, An Sermon, Frédéric Cailotto, Rik J. Lories, Silvia Monteagudo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Osteoarthritis is the most common joint disease and a global leading cause of pain and disability. Current treatment is limited to symptom relief, yet there is no disease-modifying therapy. Its multifactorial etiology includes excessive acti
Externí odkaz:
https://doaj.org/article/4f057057f8e0468d84bf190f38d38b30
Autor:
Melissa N van Tok, Nataliya G Yeremenko, Christine A Teitsma, Barbara E Kream, Véronique L Knaup, Rik J Lories, Dominique L Baeten, Leonie M van Duivenvoorde
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0163632 (2016)
Insulin like growth factor (IGF)-I can act on a variety of cells involved in cartilage and bone repair, yet IGF-I has not been studied extensively in the context of inflammatory arthritis. The objective of this study was to investigate whether IGF-I
Externí odkaz:
https://doaj.org/article/030aabf482754014b446c5a5712e7c94
Autor:
Ellen De Langhe, Greetje Vande Velde, Jeroen Hostens, Uwe Himmelreich, Benoit Nemery, Frank P Luyten, Jeroen Vanoirbeek, Rik J Lories
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43123 (2012)
BACKGROUND: In vivo high-resolution micro-computed tomography allows for longitudinal image-based measurements in animal models of lung disease. The combination of repetitive high resolution imaging with fully automated quantitative image analysis in
Externí odkaz:
https://doaj.org/article/76759d4abc9e4212b7c82f86d9e0fe84
Autor:
Jérémie Zappia, Qiao Tong, Renée Van der Cruyssen, Frederique M. F. Cornelis, Cécile Lambert, Tiago Pinto Coelho, Juliane Grisart, Erika Kague, Rik J. Lories, Marc Muller, Dirk Elewaut, Chrissy L. Hammond, Christelle Sanchez, Yves Henrotin
Publikováno v:
Bone Research, Vol 11, Iss 1, Pp 1-16 (2023)
Abstract Abnormal subchondral bone remodeling leading to sclerosis is a main feature of osteoarthritis (OA), and osteomodulin (OMD), a proteoglycan involved in extracellular matrix mineralization, is associated with the sclerotic phenotype. However,
Externí odkaz:
https://doaj.org/article/ce5742b9c2b84d36af2ac8b2853ba263
Autor:
Evelyn Houtman, Margo Tuerlings, H Eka D Suchiman, Nico Lakenberg, Frederique M F Cornelis, Hailiang Mei, Demiën Broekhuis, Rob G H H Nelissen, Rodrigo Coutinho de Almeida, Yolande F M Ramos, Rik J Lories, Luis J Cruz, Ingrid Meulenbelt
Publikováno v:
Rheumatology. OXFORD UNIV PRESS
Rheumatology
Rheumatology
Objectives To investigate whether the deiodinase inhibitor iopanoic acid (IOP) has chondroprotective properties, a mechanical stress induced model of human aged explants was used to test both repeated dosing and slow release of IOP. Methods Human ost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a5de7f0edc2ce0e93b2c98cd9f2a801
https://lirias.kuleuven.be/handle/20.500.12942/696032
https://lirias.kuleuven.be/handle/20.500.12942/696032
Autor:
Cheryl Ackert-Bicknell, Sunita K. Agarwal, Omar M.E. Albagha, Robyn S. Allen, Andrew Arnold, J.H. Duncan Bassett, John F. Bateman, Teresita Bellido, Lynda Bonewald, Eveline Boudin, Mary L. Bouxsein, Brendan F. Boyce, Niambi S. Brewer, Stephanie J. Brewster, Mike Briggs, Edward M. Brown, Matthew A. Brown, David A. Bushinsky, Wayne A. Cabral, Michael T. Collins, Michael R. Convente, Jessica Costa-Guda, Hong-Wen Deng, Olivier Devuyst, Marc K. Drezner, Emma L. Duncan, Ogo I. Egbuna, John A. Eisman, Charles R. Farber, David Feldman, Carlos R. Ferreira, William A. Gahl, Caroline M. Gorvin, Matthew W. Grol, Yan Guo, Kilian Guse, Fadil M. Hannan, Ruo-Han Hao, Ingrid A. Holm, Takashi Igarashi, Christina Jacobsen, Fjola Johannesdottir, Harald Jüppner, Frederick S. Kaplan, Gerard Karsenty, Christopher S. Kovacs, John J. Kuiper, Brendan H. Lee, Gabriela G. Loots, Rik J. Lories, Frank P. Luyten, Peter J. Malloy, Michael Mannstadt, Joan C. Marini, T. John Martin, Walter L. Miller, Orson W. Moe, Paul J. Newey, Tuan V. Nguyen, Kazuo Okamoto, Paola D. Pajevic, Christopher J. Papasian, Siân E. Piret, Stuart H. Ralston, Fernando Rivadeneira, Pamela G. Robey, Clifford J. Rosen, Merry Z.C. Ruan, Steven J. Scheinman, Scott J. Schurman, Aimy Sebastian, Yiping Shen, Eileen M. Shore, Caroline Silve, Natalie A. Sims, Alexandra K. Stanley, Adrianne Stone, Hiroshi Takayanagi, Rajesh V. Thakker, O. Will Towler, André G. Uitterlinden, Ana M. Valdes, Bram C.J. van der Eerden, Wim Van Hul, Jianwen Wei, Marc N. Wein, Lee S. Weinstein, Michael P. Whyte, Graham R. Williams, Lianping Xing, Tie-Lin Yang, Andreas Zankl, Shira G. Ziegler, Michael J. Zuscik
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f58c929c8a7231bb541d0609acde4fe9
https://doi.org/10.1016/b978-0-12-804182-6.00048-4
https://doi.org/10.1016/b978-0-12-804182-6.00048-4
Autor:
Rik J. Lories, Georg Schett
Axial spondyloarthritis is associated with different types of skeletal damage. Inflammation at the affected sites is linked with both loss of trabecular bone and new bone formation on the cortical side, potentially leading to joint or spine ankylosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e047d1399952f832b39c6b4463b0fc24
https://doi.org/10.1093/med/9780198734444.003.0010
https://doi.org/10.1093/med/9780198734444.003.0010
Autor:
Rik J. Lories, Kirsten Braem
Publikováno v:
Revue du Rhumatisme. 79:11-16
L’introduction des strategies de traitement par anti-TNF a change de facon significative les perspectives et le devenir des patients atteints de spondylarthrite ankylosante ou de spondylarthropathies apparentees. Cette avancee a egalement stimule d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3298580f9a054262ae24f1eef7a07a67
https://doi.org/10.1016/j.rhum.2011.11.003
https://doi.org/10.1016/j.rhum.2011.11.003
Autor:
Greetje Vande Velde, Jennifer Poelmans, Ellen De Langhe, Amy Hillen, Jeroen Vanoirbeek, Uwe Himmelreich, Rik J. Lories
Publikováno v:
Disease Models & Mechanisms
Disease Models & Mechanisms, Vol 9, Iss 1, Pp 91-98 (2016)
Disease Models & Mechanisms, Vol 9, Iss 1, Pp 91-98 (2016)
In vivo lung micro-computed tomography (micro-CT) is being increasingly embraced in pulmonary research because it provides longitudinal information on dynamic disease processes in a field in which ex vivo assessment of experimental disease models is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d2446507688bac31d0a73717fd8e5b6f
https://pubmed.ncbi.nlm.nih.gov/26563390
https://pubmed.ncbi.nlm.nih.gov/26563390
Autor:
Elsa, Vieira-Sousa, Leonie M, van Duivenvoorde, João E, Fonseca, Rik J, Lories, Dominique L, Baeten
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.). 67(11)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5e63339dc91dee945ed8cf30fe785c37
https://pubmed.ncbi.nlm.nih.gov/26215401
https://pubmed.ncbi.nlm.nih.gov/26215401