Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Rik G. H. Lindeboom"'
Autor:
Felix Drost, Yang An, Irene Bonafonte-Pardàs, Lisa M. Dratva, Rik G. H. Lindeboom, Muzlifah Haniffa, Sarah A. Teichmann, Fabian Theis, Mohammad Lotfollahi, Benjamin Schubert
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Recent advances in single-cell immune profiling have enabled the simultaneous measurement of transcriptome and T cell receptor (TCR) sequences, offering great potential for studying immune responses at the cellular level. However, integratin
Externí odkaz:
https://doaj.org/article/973f8f9f4a3944ad8451f6402c8d93e6
Autor:
Susan L. Kloet, Ino D. Karemaker, Lisa van Voorthuijsen, Rik G. H. Lindeboom, Marijke P. Baltissen, Raghu R. Edupuganti, Deepani W. Poramba-Liyanage, Pascal W. T. C. Jansen, Michiel Vermeulen
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
The NuRD complex plays an important role in regulating lineage commitment and cell fate during early embryonic development. Here the authors present an integrative analysis of MBD3/NuRD composition and binding in mouse embryonic stem cells and neural
Externí odkaz:
https://doaj.org/article/6ff7bd76a11f4016a379a59b7d63f1b9
Autor:
Chenqu Suo, Krzysztof Polanski, Emma Dann, Rik G. H. Lindeboom, Roser Vilarrasa-Blasi, Roser Vento-Tormo, Muzlifah Haniffa, Kerstin B. Meyer, Lisa M. Dratva, Zewen Kelvin Tuong, Menna R. Clatworthy, Sarah A. Teichmann
Publikováno v:
Nature Biotechnology.
Assessment of single-cell gene expression (single-cell RNA sequencing) and adaptive immune receptor (AIR) sequencing (scVDJ-seq) has been invaluable in studying lymphocyte biology. Here we introduce Dandelion, a computational pipeline for scVDJ-seq a
Autor:
Hannah K. Neikes, Katarzyna W. Kliza, Cathrin Gräwe, Roelof A. Wester, Pascal W. T. C. Jansen, Lieke A. Lamers, Marijke P. Baltissen, Simon J. van Heeringen, Colin Logie, Sarah A. Teichmann, Rik G. H. Lindeboom, Michiel Vermeulen
Publikováno v:
Nature Biotechnology.
Autor:
Maximillian Woodall, Ana-Maria Cujba, Kaylee B. Worlock, Katie-Marie Case, Tereza Masonou, Masahiro Yoshida, Krzysztof Polanski, Ni Huang, Rik G. H. Lindeboom, Lira Mamanova, Liam Bolt, Laura Richardson, Samuel Ellis, Machaela Palor, Thomas Burgoyne, Andreia Pinto, Dale Moulding, Timothy D. McHugh, Aarash Saleh, Eliz Kilich, Puja Mehta, Chris O’Callaghan, Jie Zhou, Wendy Barclay, Paolo De Coppi, Colin R. Butler, Heloise Vinette, Sunando Roy, Judith Breuer, Rachel C. Chambers, Wendy E. Heywood, Kevin Mills, Robert E. Hynds, Sarah A. Teichmann, Kerstin B. Meyer, Marko Z. Nikolić, Claire M. Smith
Children infected with SARS-CoV-2 rarely progress to respiratory failure, but the risk of mortality in infected people over 85 years of age remains high, despite vaccination and improving treatment options. Here, we take a comprehensive, multidiscipl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d879062a84c842d555af5dd10e4eba88
https://doi.org/10.1101/2023.01.16.524211
https://doi.org/10.1101/2023.01.16.524211
Autor:
Shuang A. Guo, Georgina S. Bowyer, John R. Ferdinand, Mailis Maes, Zewen K. Tuong, Eleanor Gilman, Mingfeng Liao, Rik G. H. Lindeboom, Masahiro Yoshida, Kaylee Worlock, Huda Gopee, Emily Stephenson, Paul A. Lyons, Kenneth G.C. Smith, Muzlifah Haniffa, Kerstin B. Meyer, Marko Z. Nikolić, Zheng Zhang, Richard G. Wunderink, Alexander V. Misharin, Gordon Dougan, Vilas Navapurkar, Sarah A. Teichmann, Andrew Conway-Morris, Menna R. Clatworthy
Obesity is common and associated with more severe COVID-19, proposed to be in part related to an adipokine-driven pro-inflammatory state. Here we analysed single cell transcriptomes from bronchiolar lavage in three adult cohorts, comparing obese (Ob,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cde1821057f37d659daf2818be914f7
https://doi.org/10.1101/2022.01.14.475727
https://doi.org/10.1101/2022.01.14.475727
Publikováno v:
Cold Spring Harbor protocols. 2019(6)
Early
Autor:
Raghu R, Edupuganti, Simon, Geiger, Rik G H, Lindeboom, Hailing, Shi, Phillip J, Hsu, Zhike, Lu, Shuang-Yin, Wang, Marijke P A, Baltissen, Pascal W T C, Jansen, Martin, Rossa, Markus, Müller, Hendrik G, Stunnenberg, Chuan, He, Thomas, Carell, Michiel, Vermeulen
Publikováno v:
Nature structuralmolecular biology. 24(10)
RNA modifications are integral to the regulation of RNA metabolism. One abundant mRNA modification is N6-methyladenosine (m6A), which affects various aspects of RNA metabolism, including splicing, translation and degradation. Current knowledge about