Dasatinib Inhibits DNA Repair after Radiotherapy Specifically in pSFK-Expressing Tumor Areas in Head and Neck Xenograft Tumors1

Autor: Stegeman, Hanneke, Span, Paul N, Rijken, Paul F J W, Cockx, Simone C, Wheeler, Deric L, Iida, Mari, van der Kogel, Albert J, Kaanders, Johannes H A M, Bussink, Johan

Src family kinases (SFKs) have been implicated in resistance to both radiation and epidermal growth factor receptor (EGFR) inhibition. Therefore, we investigated whether inhibition of SFK through dasatinib (DSB) can enhance the effect of radiotherapy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::67e60f536c532a8842908482f7675256
https://europepmc.org/articles/PMC3730016/

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Noninvasive Assessment of the Functional Neovasculature in 9L-Glioma Growing in Rat Brain by Dynamic 1H Magnetic Resonance Imaging of Gadolinium Uptake

Autor: van der Sanden, Boudewijn P. J., Rozijn, Tom H., Rijken, Paul F. J. W., Peters, Hans P. W., Heerschap, Arend, van der Kogel, Albert J., Bovée, Wim M. M. J.

Publikováno v: Journal of Cerebral Blood Flow and Metabolism; May 2000, Vol. 20 Issue: 5 p861-870, 10p

Hypoxia in relation to vasculature and proliferation in liver metastases in patients with colorectal cancer.

Autor: van Laarhoven HW; Department of Medical Oncology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands. h.vanlaarhoven@onco.umcn.nl, Kaanders JH, Lok J, Peeters WJ, Rijken PF, Wiering B, Ruers TJ, Punt CJ, Heerschap A, van der Kogel AJ

Publikováno v: International journal of radiation oncology, biology, physics [Int J Radiat Oncol Biol Phys] 2006 Feb 01; Vol. 64 (2), pp. 473-82. Date of Electronic Publication: 2005 Oct 19.