IL-17/Th17 pathway is activated in acne lesions.

Autor: Hanna-Leena Kelhälä, Riitta Palatsi, Nanna Fyhrquist, Sari Lehtimäki, Juha P Väyrynen, Matti Kallioinen, Minna E Kubin, Dario Greco, Kaisa Tasanen, Harri Alenius, Beatrice Bertino, Isabelle Carlavan, Bruno Mehul, Sophie Déret, Pascale Reiniche, Philippe Martel, Carine Marty, Ulrike Blume-Peytavi, Johannes J Voegel, Antti Lauerma

Publikováno v: PLoS ONE, Vol 9, Iss 8, p e105238 (2014)

The mechanisms of inflammation in acne are currently subject of intense investigation. This study focused on the activation of adaptive and innate immunity in clinically early visible inflamed acne lesions and was performed in two independent patient

Externí odkaz: https://doaj.org/article/2be799c3d05146d78144b913059b859a

Antimicrobial peptides - a part of innate immunity

Autor: Riitta, Palatsi, Hanna-Leena, Kelhälä

Publikováno v: Duodecim; laaketieteellinen aikakauskirja. 132(19)

Antimicrobial peptides (AMP) are evolutionary ancient molecules produced by nearly all living organisms, both prokaryotic and eukaryotic cells. More than 2000 AMPs have now been identified. These peptides are produced by most human cell types, such a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ce413618c2326ffc077675b934c67ad2
https://pubmed.ncbi.nlm.nih.gov/29188973

Long-term Safety and Efficacy of Tacrolimus Ointment for the Treatment of Atopic Dermatitis in Children

Autor: Riitta Palatsi, Graham Sharpe, Pieter G. M. Van Der Valk, Attila Dobozy, Anita Remitz, Catherine H. Smith, Wouter F M Goldschmidt, John Harper, Malcolm H.A. Rustin, Kristiina Turjanmaa

Publikováno v: Acta Dermato-Venereologica, 87, 54-61
Acta Dermato-Venereologica, 87, 1, pp. 54-61
Acta dermato-venereologica, 87(1), 54-61. Society for the Publication of Acta Dermato-Venereologica

Contains fulltext : 53193.pdf (Publisher’s version ) (Open Access) Tacrolimus ointment is a topical calcineurin inhibitor for the treatment of atopic dermatitis. The primary objective of this open-label study was to assess the long-term safety of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00ea1ee335b750678ea88e2aa64eb66d
https://doi.org/10.2340/00015555-0167

423 Isotretinoin and lymecycline treatments modify the skin microbiota in acne

Autor: Petri Auvinen, Minna E. Kubin, Antti Lauerma, V. Aho, Pedro A. B. Pereira, Kaisa Tasanen, Hanna-Leena Kelhälä, Riitta Palatsi, Nanna Fyhrquist, Lars Paulin

Publikováno v: Journal of Investigative Dermatology. 136:S232

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0b6377be9ed0a8230e556fba00545bc6
https://doi.org/10.1016/j.jid.2016.06.443

[The immune response against microbial infections in the skin--weak in atopic dermatitis and strong in psoriasis]

Autor: Riitta, Palatsi, Päivi, Hägg

Publikováno v: Duodecim; laaketieteellinen aikakauskirja. 127(2)

The innate and adaptive immune responses have been better understood after the discovery of Toll-like receptors (TLRs), antimicrobial peptides and different populations of dendritic cells. In the skin there are 1 million T-cells per 1 cm2 and 20 bill

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d389609b257c40e992ff3f8337178432
https://pubmed.ncbi.nlm.nih.gov/21442863