Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Riitta Koistinen"'
Autor:
Jannica S. Selenius, Patricia P. Silveira, Mikaela von Bonsdorff, Jari Lahti, Hannu Koistinen, Riitta Koistinen, Markku Seppälä, Johan G. Eriksson, Niko S. Wasenius
Publikováno v:
Diabetes & Metabolism Journal, Vol 48, Iss 5, Pp 960-970 (2024)
Background To investigate associations between variations in the co-expression-based brain insulin receptor polygenic score and cardiometabolic risk factors and diabetes mellitus. Methods This cross-sectional study included 1,573 participants from th
Externí odkaz:
https://doaj.org/article/84938c1dd65e4ea9907ca5c26c24d518
Autor:
Hannu Koistinen, Sonja Boyd, Johanna Arola, Kalle Jokelainen, Riitta Koistinen, Anna Lempiäinen, Kristina Hotakainen, Ulf-Håkan Stenman, Martti Färkkilä
Publikováno v:
Livers, Vol 1, Iss 4, Pp 322-329 (2021)
Primary sclerosing cholangitis (PSC) is a chronic inflammatory disease, which is associated with an increased risk of cholangiocarcinoma (CCA). Novel markers, to complement or replace CA19-9, are urgently needed for the screening of PSC-associated bi
Externí odkaz:
https://doaj.org/article/758fa20208f5431494eca0a410f85e4d
Autor:
Hannu Koistinen, Riitta Koistinen, Kristina Hotakainen, Anna Lempiäinen, Kalle Jokelainen, Martti Färkkilä, Ulf-Håkan Stenman
Publikováno v:
Analytical Biochemistry. 648:114681
Trypsin has been identified as a pancreatic protease comprising three isoenzymes, trypsin-1,-2, and-3. However, the gene for trypsinogen-3, PRSS3, also gives rise to additional variants, trypsinogen-4A and B, which differ from trypsinogen-3 only with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1d6d13a9a7e73e626b36f13c26e854a
https://doi.org/10.1016/j.ab.2022.114681
https://doi.org/10.1016/j.ab.2022.114681
Autor:
Ulf-Håkan Stenman, Johanna Wennervirta, Anne Vakkuri, Anna Lempiäinen, Hannu Koistinen, Kristina Hotakainen, Juhani A Stewart, Riitta Koistinen, Ulla-Stina Salminen
Publikováno v:
Scandinavian journal of clinical and laboratory investigation. 80(8)
The concentrations of several diagnostic markers have been found to increase dramatically in critically ill patients with a severe disturbance of normal physiological homeostasis, without indication of the diseases they are normally associated with.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7f76e77e2123c2fa30e8b7a990cd16e
https://pubmed.ncbi.nlm.nih.gov/32967482
https://pubmed.ncbi.nlm.nih.gov/32967482
Glycodelin is a glycoprotein mainly expressed in well-differentiated epithelial cells in reproductive tissues. In normal secretory endometrium, the expression of glycodelin is abundant and regulated by progesterone. In hormone-related cancers glycode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a89be6891e680d2690824ac962e0594
http://hdl.handle.net/10138/225038
http://hdl.handle.net/10138/225038
Autor:
Riitta Koistinen, Kai-Fai Lee, Philip C.N. Chiu, Ivan K. Chu, Markku Seppälä, Cheuk-Lun Lee, William S.B. Yeung, Maria Panico, Howard R. Morris, Hannu Koistinen, Anne Dell, Poh-Choo Pang, Bérangère Tissot
Publikováno v:
Diabetes. 60:909-917
OBJECTIVE Gestational diabetes mellitus (GDM) is a common metabolic disorder of pregnancy. Patients with GDM are at risk for high fetal mortality and gestational complications associated with reduced immune tolerance and abnormal carbohydrate metabol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::264b56cc8dabbac662fc4994ef234b25
https://doi.org/10.2337/db10-1186
https://doi.org/10.2337/db10-1186
Autor:
Markku Seppälä, S. O. Siu, Hannu Koistinen, Riitta Koistinen, Ivan K. Chu, Kai-Fai Lee, Cheuk-Lun Lee, Kevin K.W. Lam, Philip C.N. Chiu, William S.B. Yeung
Publikováno v:
Human Reproduction. 26:517-526
background: The maternal –fetal interface has a unique immunological response towards the implanting placenta. It is generally accepted that a T-helper type-2 (Th-2) cytokine prevailing environment is important in pregnancy. The proportion of Th-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f34e59b88ccd2b07859a00c308f421af
https://doi.org/10.1093/humrep/deq381
https://doi.org/10.1093/humrep/deq381
Autor:
Fernando Larrea, Marta Durand, Riitta Koistinen, Markku Seppälä, José Luis Rodríguez, Elena Zambrano, Mayel Chirinos
Publikováno v:
Contraception. 82:526-533
Background The study was conducted to assess the effects of levonorgestrel (LNG) on hormonal behavior and on the secretory pattern of intrauterine glycodelin at the midcycle of ovulatory women. Study Design Thirty healthy sterilized women with normal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8497571d4a1acb60408a3f5f46be10f3
https://doi.org/10.1016/j.contraception.2010.05.015
https://doi.org/10.1016/j.contraception.2010.05.015
Autor:
Päivi Heikkilä, Riitta Koistinen, Heli Nevanlinna, Tuomas Heikkinen, Hannu Koistinen, Laura Hautala, Kristiina Aittomäki, Dario Greco, Carl Blomqvist
Publikováno v:
Breast Cancer Research and Treatment. 128:85-95
Glycodelin (encoded by PAEP gene) is a secreted lipocalin protein mainly expressed in reproductive tissues, but also in several tumour types. In the breast, glycodelin is expressed both in normal epithelial and cancerous tissue. To investigate the as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b127674ee26268540052b4a9ec71fe2e
https://doi.org/10.1007/s10549-010-1065-y
https://doi.org/10.1007/s10549-010-1065-y
Autor:
Laura Hautala, Markku Seppälä, Wsb Yeung, Philip C.N. Chiu, Riitta Koistinen, Hannu Koistinen
Publikováno v:
European Journal of Endocrinology. 160:121-133
Glycodelin is an endocrine-regulated glycoprotein that has significant effects on immune cells, apoptosis, reproduction, cell adhesion, differentiation and cancer. In reproduction, glycodelin contributes to capacitation and immunoprotection of sperma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ec9c6a0b4a8fed85f333f3a6049c71
https://doi.org/10.1530/eje-08-0756
https://doi.org/10.1530/eje-08-0756