Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Riina, Harjumäki"'
Autor:
Chris S. Pridgeon, Kerttu Airavaara, Julia Monola, Alisa Jokela, Daniel Palmer, Marjo Yliperttula, Riina Harjumäki
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Variations in oxygen level affect the phenotype of cells and extracellular vesicles (EVs). Depending on the metabolic oxygen demand of cells, hypoxic cell culture can produce conditions more like those found in vivo, and with appropriate oxy
Externí odkaz:
https://doaj.org/article/d9589f90be5f4d57bced0c9fab572e63
Autor:
Roberta Teixeira Polez, Ngoc Huynh, Chris S. Pridgeon, Juan José Valle-Delgado, Riina Harjumäki, Monika Österberg
Publikováno v:
Materials Today Bio, Vol 26, Iss , Pp 101065- (2024)
The recent FDA decision to eliminate animal testing requirements emphasises the role of cell models, such as spheroids, as regulatory test alternatives for investigations of cellular behaviour, drug responses, and disease modelling. The influence of
Externí odkaz:
https://doaj.org/article/2d215124082346bf86342a3ac679c8e5
Autor:
Mariia S. Bogacheva, Riina Harjumäki, Emilia Flander, Ara Taalas, Margarita A. Bystriakova, Marjo Yliperttula, Xiaoqiang Xiang, Alan W. Leung, Yan-Ru Lou
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The generation of human stem cell-derived spheroids and organoids represents a major step in solving numerous medical, pharmacological, and biological challenges. Due to the advantages of three-dimensional (3D) cell culture systems and the diverse ap
Externí odkaz:
https://doaj.org/article/6d841bf2d3aa4b51b77f7a6e9c7edadf
Autor:
Elle Koivunotko, Jasmi Snirvi, Arto Merivaara, Riina Harjumäki, Swarna Rautiainen, Minna Kelloniemi, Kirsi Kuismanen, Susanna Miettinen, Marjo Yliperttula, Raili Koivuniemi
Publikováno v:
Biomedicines, Vol 10, Iss 10, p 2584 (2022)
Adipose-derived mesenchymal stromal cells (ASCs) hold great potential for cellular therapies by having immunomodulatory behavior and tissue regenerative properties. Due to the capability of ASCs to differentiate into endothelial cells (ECs) and other
Externí odkaz:
https://doaj.org/article/ace6f881a026423aa1db3eef1b57369c
Autor:
Yan-Ru Lou, Riina Harjumäki, Xue Zhang, Marjo Yliperttula, Muhammad Farooq, Robertus Wahyu N. Nugroho, Juan José Valle-Delgado, Monika Österberg
Publikováno v:
ACS Applied Bio Materials. 3:1406-1417
Transmembrane protein integrins play a key role in cell adhesion. Cell-biomaterial interactions are affected by integrin expression and conformation, which are actively controlled by cells. Although integrin structure and function have been studied i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cebea2951e09dcaa907407be849c827e
https://doi.org/10.1021/acsabm.9b01073
https://doi.org/10.1021/acsabm.9b01073
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8221, p 8221 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
CYP2E1 is one of the fifty-seven cytochrome P450 genes in the human genome and is highly conserved. CYP2E1 is a unique P450 enzyme because its heme iron is constitutively in the high spin state, allowing direct reduction of, e.g., dioxygen, causing t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f20e9516629a57d01494b7b39bb80228
https://www.mdpi.com/1422-0067/22/15/8221
https://www.mdpi.com/1422-0067/22/15/8221
Autor:
Marjo Yliperttula, Xue Zhang, Robertus Wahyu N. Nugroho, Monika Österberg, Yan-Ru Lou, Riina Harjumäki, Juan José Valle-Delgado
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 173:571-580
Biomaterials of different nature have been and are widely studied for various biomedical applications. In many cases, biomaterial assemblies are designed to mimic biological systems. Although biomaterials have been thoroughly characterized in many as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1bf488297bdf7fd4168b52fb60b8d0f
https://doi.org/10.1016/j.colsurfb.2018.09.073
https://doi.org/10.1016/j.colsurfb.2018.09.073
Autor:
Xue, Zhang, Tapani, Viitala, Riina, Harjumäki, Alma, Kartal-Hodzic, Juan José, Valle-Delgado, Monika, Österberg
Publikováno v:
Journal of colloid and interface science. 584
The development of in vitro cell models that mimic cell behavior in organs and tissues is an approach that may have remarkable impact on drug testing and tissue engineering applications in the future. Plant-based, chemically unmodified cellulose nano
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::960f2e2f0f509d7e26c312997c790b08
https://pubmed.ncbi.nlm.nih.gov/33069029
https://pubmed.ncbi.nlm.nih.gov/33069029
Autor:
Yan-Ru Lou, Robertus Wahyu N. Nugroho, Xue Zhang, Marjo Yliperttula, Riina Harjumäki, Monika Österberg, Juan José Valle-Delgado
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-3 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f6cdb96d365b256d97990ee107628f7
https://doi.org/10.1038/s41598-020-65140-8
https://doi.org/10.1038/s41598-020-65140-8
Autor:
Juan José Valle-Delgado, Yan-Ru Lou, Marjo Yliperttula, Xue Zhang, Robertus Wahyu N. Nugroho, Riina Harjumäki, Monika Österberg
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
In vitro cell culture or tissue models that mimic in vivo cellular response have potential in tissue engineering and regenerative medicine, and are a more economical and accurate option for drug toxicity tests than animal experimentation. The design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::047ac5337667f78056c1cfdd84e3c1da
https://pubmed.ncbi.nlm.nih.gov/32451383
https://pubmed.ncbi.nlm.nih.gov/32451383