Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Riikka Lampinen"'
Autor:
Laura Mussalo, Riikka Lampinen, Simone Avesani, Táňa Závodná, Zdeněk Krejčík, Juho Kalapudas, Elina Penttilä, Heikki Löppönen, Anne M. Koivisto, Tarja Malm, Jan Topinka, Rosalba Giugno, Pasi Jalava, Katja M. Kanninen
Publikováno v:
Redox Biology, Vol 75, Iss , Pp 103272- (2024)
Constituents of air pollution, the ultrafine particles (UFP) with a diameter of ≤0.1 μm, are considerably related to traffic emissions. Several studies link air pollution to Alzheimer's disease (AD), yet the exact relationship between the two rema
Externí odkaz:
https://doaj.org/article/5fe4cf95d0a6478bb39e07f3433e085c
Autor:
Muhammad Ali Shahbaz, Suvi Kuivanen, Riikka Lampinen, Laura Mussalo, Tomáš Hron, Táňa Závodná, Ravi Ojha, Zdeněk Krejčík, Liudmila Saveleva, Numan Ahmad Tahir, Juho Kalapudas, Anne M. Koivisto, Elina Penttilä, Heikki Löppönen, Prateek Singh, Jan Topinka, Olli Vapalahti, Sweelin Chew, Giuseppe Balistreri, Katja M. Kanninen
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-23 (2023)
Abstract Background The neurological effects of the coronavirus disease of 2019 (COVID-19) raise concerns about potential long-term consequences, such as an increased risk of Alzheimer's disease (AD). Neuroinflammation and other AD-associated patholo
Externí odkaz:
https://doaj.org/article/343edc01917c4050b01c3190ca3636ea
Autor:
Mariia Ivanova, Irina Belaya, Nina Kucháriková, Izaque de Sousa Maciel, Liudmila Saveleva, Arto Alatalo, Ilona Juvonen, Navjot Thind, Clarisse Andrès, Riikka Lampinen, Sweelin Chew, Katja M. Kanninen
Publikováno v:
Neurobiology of Disease, Vol 191, Iss , Pp 106410- (2024)
Integrins are receptors that have been linked to various brain disorders, including Alzheimer's disease (AD), the most prevalent neurodegenerative disorder. While Integrin beta-3 (ITGB3) is known to participate in multiple cellular processes such as
Externí odkaz:
https://doaj.org/article/e8c1910a22c941d385b1b2eb420e0f39
Autor:
Riikka Lampinen, Irina Belaya, Liudmila Saveleva, Jeffrey R. Liddell, Dzhessi Rait, Mikko T. Huuskonen, Raisa Giniatullina, Annika Sorvari, Liisi Soppela, Nikita Mikhailov, Isabella Boccuni, Rashid Giniatullin, Marcela Cruz-Haces, Julia Konovalova, Marja Koskuvi, Andrii Domanskyi, Riikka H. Hämäläinen, Gundars Goldsteins, Jari Koistinaho, Tarja Malm, Sweelin Chew, Kirsi Rilla, Anthony R. White, Nicholas Marsh-Armstrong, Katja M. Kanninen
Publikováno v:
Neurobiology of Disease, Vol 170, Iss , Pp 105753- (2022)
Under physiological conditions in vivo astrocytes internalize and degrade neuronal mitochondria in a process called transmitophagy. Mitophagy is widely reported to be impaired in neurodegeneration but it is unknown whether and how transmitophagy is a
Externí odkaz:
https://doaj.org/article/90b3b33e12fd4d749b99c1ac7e4e3bbb
Autor:
Rosamaria Lombardo, Marika Ruponen, Jarkko Rautio, Carla Ghelardini, Lorenzo Di Cesare Mannelli, Laura Calosi, Daniele Bani, Riikka Lampinen, Katja M. Kanninen, Anne M. Koivisto, Elina Penttilä, Heikki Löppönen, Rosario Pignatello
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1554 (2023)
Clozapine (CZP) is the only effective drug in schizophrenia resistant to typical antipsychotics. However, existing dosage forms (oral or orodispersible tablets, suspensions or intramuscular injection) show challenging limitations. After oral administ
Externí odkaz:
https://doaj.org/article/a9af83064787401fb31dedc14b1bfd1e
Autor:
Sweelin Chew, Riikka Lampinen, Liudmila Saveleva, Paula Korhonen, Nikita Mikhailov, Alexandra Grubman, Jose M. Polo, Trevor Wilson, Mika Komppula, Teemu Rönkkö, Cheng Gu, Alan Mackay-Sim, Tarja Malm, Anthony R. White, Pasi Jalava, Katja M. Kanninen
Publikováno v:
Particle and Fibre Toxicology, Vol 17, Iss 1, Pp 1-15 (2020)
Abstract Background The adverse effects of air pollutants including particulate matter (PM) on the central nervous system is increasingly reported by epidemiological, animal and post-mortem studies in the last decade. Oxidative stress and inflammatio
Externí odkaz:
https://doaj.org/article/1c2a6611524442c9936f8b5edcd03f3f
Autor:
Laura M. Rantanen, Maina Bitar, Riikka Lampinen, Romal Stewart, Hazel Quek, Lotta E. Oikari, Carla Cunί-Lόpez, Ratneswary Sutharsan, Gayathri Thillaiyampalam, Jamila Iqbal, Daniel Russell, Elina Penttilä, Heikki Löppönen, Juha-Matti Lehtola, Toni Saari, Sanna Hannonen, Anne M. Koivisto, Larisa M. Haupt, Alan Mackay-Sim, Alexandre S. Cristino, Katja M. Kanninen, Anthony R. White
Publikováno v:
Cells, Vol 11, Iss 20, p 3258 (2022)
An early symptom of Alzheimer’s disease (AD) is an impaired sense of smell, for which the molecular basis remains elusive. Here, we generated human olfactory neurosphere-derived (ONS) cells from people with AD and mild cognitive impairment (MCI), a
Externí odkaz:
https://doaj.org/article/dca05e7e61d14b3aa34487459c0f0668
Autor:
Riikka Lampinen, Veronika Górová, Simone Avesani, Jeffrey R. Liddell, Elina Penttilä, Táňa Závodná, Zdeněk Krejčík, Juha-Matti Lehtola, Toni Saari, Juho Kalapudas, Sanna Hannonen, Heikki Löppönen, Jan Topinka, Anne M. Koivisto, Anthony R. White, Rosalba Giugno, Katja M. Kanninen
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 8, p 4123 (2022)
Olfactory function, orchestrated by the cells of the olfactory mucosa at the rooftop of the nasal cavity, is disturbed early in the pathogenesis of Alzheimer’s disease (AD). Biometals including zinc and calcium are known to be important for sense o
Externí odkaz:
https://doaj.org/article/24e6ca5098954547b4ce989fae2cf1f7
Autor:
Riikka Lampinen, Mohammad Feroze Fazaludeen, Simone Avesani, Tiit Örd, Elina Penttilä, Juha-Matti Lehtola, Toni Saari, Sanna Hannonen, Liudmila Saveleva, Emma Kaartinen, Francisco Fernández Acosta, Marcela Cruz-Haces, Heikki Löppönen, Alan Mackay-Sim, Minna U. Kaikkonen, Anne M. Koivisto, Tarja Malm, Anthony R. White, Rosalba Giugno, Sweelin Chew, Katja M. Kanninen
Publikováno v:
Cells, Vol 11, Iss 4, p 676 (2022)
Olfaction is orchestrated by olfactory mucosal cells located in the upper nasal cavity. Olfactory dysfunction manifests early in several neurodegenerative disorders including Alzheimer’s disease, however, disease-related alterations to the olfactor
Externí odkaz:
https://doaj.org/article/f37964f4ad0445378ce4d9197ff96e19
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Ferroptosis is a newly described form of regulated cell death, distinct from apoptosis, necroptosis and other forms of cell death. Ferroptosis is induced by disruption of glutathione synthesis or inhibition of glutathione peroxidase 4, exacerbated by
Externí odkaz:
https://doaj.org/article/d4add537cfc54d5f9e5a0cde51875d77