Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Riikka Hynynen"'
Autor:
Jaakko Mattila, Essi Havula, Erja Suominen, Mari Teesalu, Ida Surakka, Riikka Hynynen, Helena Kilpinen, Juho Väänänen, Iiris Hovatta, Reijo Käkelä, Samuli Ripatti, Thomas Sandmann, Ville Hietakangas
Publikováno v:
Cell Reports, Vol 13, Iss 2, Pp 350-364 (2015)
The ChREBP/Mondo-Mlx transcription factors are activated by sugars and are essential for sugar tolerance. They promote the conversion of sugars to lipids, but beyond this, their physiological roles are insufficiently understood. Here, we demonstrate
Externí odkaz:
https://doaj.org/article/bc787bf3a50e4994b72aac3c86df2c22
Autor:
Riikka Hynynen, Monika Suchanek, Johanna Spandl, Nils Ba¨ck, Christoph Thiele, Vesa M. Olkkonen
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 7, Pp 1305-1315 (2009)
Oxysterol binding protein-related protein 2 (ORP2) is a member of the oxysterol binding protein family, previously shown to bind 25-hydroxycholesterol and implicated in cellular cholesterol metabolism. We show here that ORP2 also binds 22(R)-hydroxyc
Externí odkaz:
https://doaj.org/article/a2ab75bf10604a2eb8adc7ef01201110
Autor:
Ville Hietakangas, Krista Kokki, Riikka Hynynen, Reijo Käkelä, Kiran Hasygar, Onur Deniz, Josef Gullmets, Hanna Ruhanen, Ying Liu
Publikováno v:
EMBO Reports
Energy storage and growth are coordinated in response to nutrient status of animals. How nutrient‐regulated signaling pathways control these processes in vivo remains insufficiently understood. Here, we establish an atypical MAP kinase, ERK7, as an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91b140f470043c6ab104ec7da4f9f9f3
http://europepmc.org/articles/PMC7857433
http://europepmc.org/articles/PMC7857433
Autor:
Vesa M. Olkkonen, Johanna Spandl, Monika Suchanek, Nils Bäck, Riikka Hynynen, Christoph Thiele
Publikováno v:
The Journal of Lipid Research; Vol 50
The Journal of Lipid Research
Journal of Lipid Research, Vol 50, Iss 7, Pp 1305-1315 (2009)
The Journal of Lipid Research
Journal of Lipid Research, Vol 50, Iss 7, Pp 1305-1315 (2009)
Oxysterol binding protein-related protein 2 (ORP2) is a member of the oxysterol binding protein family, previously shown to bind 25-hydroxycholesterol and implicated in cellular cholesterol metabolism. We show here that ORP2 also binds 22(R)-hydroxyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0fd8d11c7ae5fb0421a46739cb5a012
Autor:
Riikka Hynynen, Vesa M. Olkkonen
Publikováno v:
Molecular Aspects of Medicine
Molecular Aspects of Medicine; Vol 30
Molecular Aspects of Medicine; Vol 30
Oxysterols are oxidized derivatives of cholesterol or by-products of cholesterol biosynthesis with multiple functions. Even though they are heterogeneous in their biological activities, they have the common property of transferring between membranes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa84ba146b2a8edbcf97d5c678671874
Autor:
Reijo Käkelä, Ida Surakka, Helena Kilpinen, Erja Suominen, Juho Väänänen, Mari Teesalu, Riikka Hynynen, Thomas Sandmann, Ville Hietakangas, Jaakko Mattila, Iiris Hovatta, Samuli Ripatti, Essi Havula
Publikováno v:
Cell Reports, Vol 13, Iss 2, Pp 350-364 (2015)
The ChREBP/Mondo-Mlx transcription factors are activated by sugars and are essential for sugar tolerance. They promote the conversion of sugars to lipids, but beyond this, their physiological roles are insufficiently understood. Here, we demonstrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07cf422619c8ad0bfa7f12411b81b073
https://pubmed.ncbi.nlm.nih.gov/26440885
https://pubmed.ncbi.nlm.nih.gov/26440885
Autor:
Esa Kuismanen, Vesa M. Olkkonen, Markku Lehto, Riikka Hynynen, Katja Karjalainen, Kati Hyvärinen
Publikováno v:
Experimental Cell Research. 310:445-462
The intracellular targeting determinants of oxysterol binding protein (OSBP)-related protein 3 (ORP3) were studied using a series of truncated and point mutated constructs. The pleckstrin homology (PH) domain of ORP3 binds the phosphoinositide-3-kina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd0c4d425ed8d69feb81617595a77662
https://doi.org/10.1016/j.yexcr.2005.08.003
https://doi.org/10.1016/j.yexcr.2005.08.003
Autor:
Christoph Thiele, Riikka Hynynen, Marie Johansson, Hannu Saarinen, Markku Lehto, Monika Suchanek, Anna Radzikowska, Vesa M. Olkkonen, Gerd Wohlfahrt
OSBP (oxysterol-binding protein) homologues, ORPs (OSBP-related proteins), constitute a 12-member family in mammals. We employed an in vitro [3H]25OH (25-hydroxycholesterol)-binding assay with purified recombinant proteins as well as live cell photo-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e14c12d1f315ebd747a48b05501c59b3
https://europepmc.org/articles/PMC2267293/
https://europepmc.org/articles/PMC2267293/
Autor:
Riikka Hynynen, Sari Lusa, Saara Laitinen, Reijo Käkelä, Elina Ikonen, Kimmo Tanhuanpää, Vesa M. Olkkonen, Christian Ehnholm, Pentti Somerharju
Publikováno v:
The Biochemical journal. 390(Pt 1)
ORP2 [OSBP (oxysterol-binding protein)-related protein 2] belongs to the 12-member mammalian ORP gene/protein family. We characterize in the present study the effects of inducible ORP2 overexpression on cellular cholesterol metabolism in HeLa cells a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ee6b310a7b5a669ed12f5c2fdfbf535
https://pubmed.ncbi.nlm.nih.gov/15859942
https://pubmed.ncbi.nlm.nih.gov/15859942
Autor:
Olivier Beaslas, Riikka Hynynen, Julia Perttilä, Terhi Vihervaara, You Zhou, Vesa M. Olkkonen
Publikováno v:
Chemistry and Physics of Lipids. 160:S5-S6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01660b4aac4a9eb720bacc9eaa73f428
https://doi.org/10.1016/j.chemphyslip.2009.06.103
https://doi.org/10.1016/j.chemphyslip.2009.06.103