Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Riichi Tawa"'
Publikováno v:
Journal of Controlled Release. 105:23-31
Oral gentamicin (GM) therapy has been challenged by formulating GM in oral solid preparation. GM was dispersed with a surfactant used for the self-microemulsifying drug delivery system (SMEDDS), PEG-8 caprylic/capric glycerides (Labrasol), and the mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39f594ecc9e3f4303f79a2341c2bf5b5
https://doi.org/10.1016/j.jconrel.2005.03.017
https://doi.org/10.1016/j.jconrel.2005.03.017
Autor:
Zhaopeng Hu, Rama Prasad Yv̄, Nobuhito Shibata, Kanji Takada, Riichi Tawa, Takahiro Konishi, Makoto Ishida
Publikováno v:
International Journal of Pharmaceutics. 234:223-235
In our previous study, we had reported that Labrasol has a good gastrointestinal (GI) absorption enhancing effect on poorly absorbable drugs. In order to improve further absorption enhancing effect of Labrasol on gentamicin (GM), which is a represent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51d581c9cba171a5889c1618235d38ab
https://doi.org/10.1016/s0378-5173(01)00967-x
https://doi.org/10.1016/s0378-5173(01)00967-x
Autor:
Nobuyuki Masuyama, Akihiro Nakayama, Hiromu Sakurai, Masaaki Ebara, Katsuyuki Nakajima, Riichi Tawa, Hiroyuki Fukuda, Keiji Suzuki
Publikováno v:
The Journal of Trace Elements in Experimental Medicine. 15:31-45
Metallothionein (MT) has been described as a cell-protective protein that binds several heavy metals. In mammals, MT plays an important physiological role that includes detoxifying heavy metals, accumulating essential trace elements in cells to maint
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54ea6b4d7153266e78e6a20c87ac01cd
https://doi.org/10.1002/jtra.10003
https://doi.org/10.1002/jtra.10003
Autor:
Yae Fujisawa, Hiromu Sakurai, Riichi Tawa, Kan Kanamori, Keiko Uchida, Seiki Fujimoto, Junko Taniyama, Takashi Nagaoka
Publikováno v:
Journal of Pharmacy and Pharmacology. 51:119-124
Because it has been confirmed that the vanadyl(IV) ion and its complexes act as insulin mimetics, a new organic vanadyl complex, (N-pyridylmethylaspartate)oxovanadium (VOPASP) with VO(N2O2) coordination mode, was prepared. Development of a simple and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3176337ae7fc19c4321bc0da3974f01d
https://doi.org/10.1211/0022357991772213
https://doi.org/10.1211/0022357991772213
Publikováno v:
Journal of Chromatography A. 812:141-150
A simple precolumn derivatisation method for the determination of aminoglycoside antibiotics (AGs) is described. The stability of the o-phthalaldehyde (OPA) derivatives of the AGs obtain using beta-mercaptopropionic acid (beta-MP) was investigated by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b0c270fa7ed3e39b7dd7ef743c91529
https://doi.org/10.1016/s0021-9673(98)00342-2
https://doi.org/10.1016/s0021-9673(98)00342-2
Publikováno v:
Chemical and Pharmaceutical Bulletin. 46:1383-1387
Baicalein (5,6,7-trihydroxy-2-phenyl-4H-1-benzopyran-4-one), a naturally occurring flavonoid, was found to prevent human dermal fibroblast cell damage induced by reactive oxygen species such as hydrogen peroxide (H2O2), tert-butyl hydroperoxide (BuOO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00d4a18f92738e5238a635601868e1dc
https://doi.org/10.1248/cpb.46.1383
https://doi.org/10.1248/cpb.46.1383
Autor:
Hiromu Sakurai, Riichi Tawa
Publikováno v:
Analytical Letters. 30:2811-2825
Simple and rapid chemiluminescence (CL) assays for H2O2, •OH, •O2 − and 1O2 using 5-amino-2,3-dihydro-1,4-phthalazinedione (luminol) or 2-methyl-6-phenyl-3,7-dihydroimidazo[1,2-α]pyrazin-3-one (CLA) as CL reagents were developed. The means of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2fb92896a3d431236bca0da42db2017
https://doi.org/10.1080/00032719708001824
https://doi.org/10.1080/00032719708001824
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 7:489-494
Site-specific double stranded DNA breaks by ·OH radicals generated from podophyllotoxin related compounds in the presence of Cu(II) ion were investigated and the neighboring effects of 5-methylcytosine on double stranded DNA cleavage, especially on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9f3004b80f8a93f3ccc35496e869eab
https://doi.org/10.1016/s0960-894x(97)00015-2
https://doi.org/10.1016/s0960-894x(97)00015-2
Publikováno v:
Biochemical Pharmacology. 47:1920-1925
Site-specific DNA cleavage in the presence of Cu(II) complexes of podophyllotoxin derivatives was investigated with a modified Sanger sequencing method. Cu(II) complexes of 4'-demethylepipodophyllotoxin (DEPD) and syringic acid (SA) cleaved M13mp18 s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::507231e7552eec274c3e583c2399eec6
https://doi.org/10.1016/0006-2952(94)90324-7
https://doi.org/10.1016/0006-2952(94)90324-7
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 653:211-216
The change of the methylation of CpG in the CCGG sequence of brain and liver DNAs of mice during late fetal and suckling periods was determined by high-performance liquid chromatography using a reversed-phase column and 0.1 M phosphate buffer (pH 6.0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::248904ab27b79e26ab8f08489c19e54f
https://doi.org/10.1016/0378-4347(93)e0421-l
https://doi.org/10.1016/0378-4347(93)e0421-l