Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Rihua Jin"'
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-12 (2021)
Abstract Temozolomide (TMZ) is the mainstream chemotherapeutic drug for treating glioblastoma multiforme (GBM), but the intrinsic or acquired chemoresistance to TMZ has become the leading clinical concern, which is related to the repair of DNA alkyla
Externí odkaz:
https://doaj.org/article/1a1b2228eb7a4fe3b2c5cace543001b5
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Astrocytes are the most widely distributed and abundant glial cells in the central nervous system (CNS). Neurodegenerative diseases (NDDs) are a class of diseases with a slow onset, progressive progression, and poor prognosis. Common clinical NDDs in
Externí odkaz:
https://doaj.org/article/c75be3981a3141d396d4c334799ebd6f
Autor:
Sheng Zhong, Weihang Li, Yang Bai, Bo Wu, Xinhui Wang, Shanshan Jiang, Yingjing Zhao, Jiaxin Ren, Hui Li, Rihua Jin
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216678 (2019)
ObjectiveThis study aimed to screen lead compounds and medication candidates from drug library (ZINC database) which has potential agonist effect targeting STING protein.Methods and materialsA series of computer-aided virtual screening techniques wer
Externí odkaz:
https://doaj.org/article/b4c421d6938d47b4bcd1b0f5ec273d70
Publikováno v:
Medicine. 102:e33846
Autor:
Weihang Li, Shanshan Jiang, Yujie Shao, Hao Wang, Sheng Zhong, Zheng Jin, Hui Li, Sitong Chen, Lianhua Piao, Yu Zhang, Rihua Jin, Bo Wu, Jiaxin Ren, Luwei Lucy Liu, Jingyi Liu
Publikováno v:
Aging (Albany NY)
Indoleamine 2,3-Dioxygenase (IDO), is a speed limiting enzyme that catalyzes the decomposition and metabolism of Tryptophan along Tryptophan-IDO-Kynurenine pathway [1]. Tryptophan is a necessary amino acid for activating cell growth and metabolism. A
Publikováno v:
OncoTargets and Therapy. 13:1073-1086
Background Glioma is the most commonly diagnosed primary brain tumor. Dysregulation of long non-coding RNA (lncRNA) is associated with initiation and development of various cancer types including glioma. Methods The relative expression of lncRNA was
Publikováno v:
Cell Death Discovery
Cell Death Discovery, Vol 7, Iss 1, Pp 1-12 (2021)
Cell Death Discovery, Vol 7, Iss 1, Pp 1-12 (2021)
Temozolomide (TMZ) is the mainstream chemotherapeutic drug for treating glioblastoma multiforme (GBM), but the intrinsic or acquired chemoresistance to TMZ has become the leading clinical concern, which is related to the repair of DNA alkylation site
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience
Astrocytes are the most widely distributed and abundant glial cells in the central nervous system (CNS). Neurodegenerative diseases (NDDs) are a class of diseases with a slow onset, progressive progression, and poor prognosis. Common clinical NDDs in
Autor:
Chunyang Liu, Xinyu Hong, Yubo Wang, Yue Cao, Zheng Jin, Liyan Zhao, Gang Zhao, Rihua Jin, Yining Jiang
Publikováno v:
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. 47(9)
Background The objective of this study is to determine the population-based estimates of the epidemiology, incidence, and outcomes of spinal meningiomas. Methods The data of patients with spinal meningiomas diagnosed between 2004 and 2016 were extrac
Publikováno v:
Journal of drug targeting. 29(3)
The blood-brain barrier (BBB) and complex tumour immunosuppressive micro-environment posed austere challenges for combatting brain tumours such as the glioblastoma. In this study, we have developed a novel dual functional dendrimer drug delivery syst