Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Rihan El Bezawy"'
Autor:
Valentina Zuco, Sandro Pasquali, Monica Tortoreto, Silvia Brich, Stefano Percio, Gian Paolo Dagrada, Chiara Colombo, Roberta Sanfilippo, Calogero Lauricella, Mrinal Gounder, Rihan El Bezawy, Marta Barisella, Angelo Paolo Dei Tos, Paolo Giovanni Casali, Alessandro Gronchi, Silvia Stacchiotti, Nadia Zaffaroni
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-12 (2021)
Abstract Background Dedifferentiated liposarcoma (DDLPS), a tumor that lacks effective treatment strategies and is associated with poor outcomes, expresses amplified MDM2 in the presence of wild-type p53. MDM2 ubiquitination of p53 facilitates its XP
Externí odkaz:
https://doaj.org/article/7da031e33ebf48729291cb024f6f6183
Autor:
Rihan El Bezawy, Stella Tinelli, Monica Tortoreto, Valentina Doldi, Valentina Zuco, Marco Folini, Claudio Stucchi, Tiziana Rancati, Riccardo Valdagni, Paolo Gandellini, Nadia Zaffaroni
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-11 (2019)
Abstract Background Radiotherapy is one of the main treatment options for non-metastatic prostate cancer (PCa). Although treatment technical optimization has greatly improved local tumor control, a considerable fraction of patients still experience r
Externí odkaz:
https://doaj.org/article/027135c8d7f44307a37a1e7c2afbf0e1
Autor:
Rihan El Bezawy, Michelandrea De Cesare, Marzia Pennati, Marcello Deraco, Paolo Gandellini, Valentina Zuco, Nadia Zaffaroni
Publikováno v:
Journal of Hematology & Oncology, Vol 10, Iss 1, Pp 1-14 (2017)
Abstract Background The value of microRNAs (miRNAs) as novel targets for cancer therapy is now widely recognized. However, no information is currently available on the expression/functional role of miRNAs in diffuse malignant peritoneal mesothelioma
Externí odkaz:
https://doaj.org/article/5fcd33ccb4024852870b744b30bd3645
Autor:
Silvia Martini, Valentina Zuco, Monica Tortoreto, Stefano Percio, Elisa Campi, Rihan El Bezawy, Valentina Doldi, Yosef Landesman, Marzia Pennati, Nadia Zaffaroni
Publikováno v:
Pharmaceuticals, Vol 14, Iss 6, p 523 (2021)
Triple-negative breast cancer (TNBC) is an aggressive disease with limited therapeutic options. Here, we pursued a combinatorial therapeutic approach to enhance the activity of selinexor, the first-in-class XPO1 inhibitor, by miR-34a ectopic expressi
Externí odkaz:
https://doaj.org/article/b5d9b2022b374d4caa774c33c5ffe47c
Autor:
Federica Rotundo, Denis Cominetti, Rihan El Bezawy, Stefano Percio, Valentina Doldi, Monica Tortoreto, Valentina Zuco, Riccardo Valdagni, Nadia Zaffaroni, Paolo Gandellini
Publikováno v:
Cells, Vol 9, Iss 2, p 435 (2020)
The development of novel therapies or the improvement of currently used approaches to treat prostate cancer (PCa), the most frequently diagnosed male tumor in developed countries, is an urgent need. In this regard, the functional characterization of
Externí odkaz:
https://doaj.org/article/590c713293aa45f4aa3a6a7bd25e6785
Autor:
Rihan El Bezawy, Stefano Percio, Chiara Maura Ciniselli, Michelandrea De Cesare, Gennaro Colella, Matteo Dugo, Silvia Veneroni, Valentina Doldi, Silvia Martini, Dario Baratti, Shigeki Kusamura, Paolo Verderio, Marcello Deraco, Paolo Gandellini, Nadia Zaffaroni, Valentina Zuco
Publikováno v:
Cancer gene therapy. 29(10)
Diffuse malignant peritoneal mesothelioma (DMPM) is a rare and rapidly lethal tumor, poorly responsive to conventional treatments. In this regards, the identification of molecular alterations underlying DMPM onset and progression might be exploited t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53dfb31674ba20e1ded6c7abf0c0b75a
https://pubmed.ncbi.nlm.nih.gov/35352023
https://pubmed.ncbi.nlm.nih.gov/35352023
Autor:
Mara Lecchi, Maurizio Colecchia, C. Marenghi, Melanie Claps, Mario Catanzaro, Riccardo Valdagni, Valentina Doldi, Paolo Gandellini, Paolo Verderio, Rihan El Bezawy, Barbara Avuzzi, Nadia Zaffaroni, Tiziana Rancati, Fabio Badenchini, Chiara Maura Ciniselli, Elisa Campi
Publikováno v:
Cancers
Volume 13
Issue 10
Cancers, Vol 13, Iss 2433, p 2433 (2021)
Volume 13
Issue 10
Cancers, Vol 13, Iss 2433, p 2433 (2021)
Simple Summary Active surveillance (AS) has evolved as an alternative to radical treatment for potentially indolent prostate cancer. However, current selection criteria for entering AS are suboptimal, and a significant percentage of patients disconti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8602c2190d66956527fab47d4182c3ea
Publikováno v:
Cancers, Vol 13, Iss 2380, p 2380 (2021)
Cancers
Cancers
Simple Summary Prostate cancer is one of the most common and lethal tumors in men worldwide. Due to the high heterogeneity of the disease, the optimal treatment choice for individual patients is very challenging, thus leading to treatment failure cau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23bd904d8549e2918f4befabab755f62
https://www.mdpi.com/2072-6694/13/10/2380
https://www.mdpi.com/2072-6694/13/10/2380
Autor:
Sandro Pasquali, Monica Tortoreto, Calogero Lauricella, Gianpaolo Dagrada, Alessandro Gronchi, Roberta Sanfilippo, Silvia Stacchiotti, Marta Barisella, Chiara Colombo, Stefano Percio, Valentina Zuco, Mrinal M. Gounder, Paolo G. Casali, Rihan El Bezawy, Silvia Brich, Nadia Zaffaroni, Angelo Paolo Dei Tos
Publikováno v:
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-12 (2021)
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-12 (2021)
Background Dedifferentiated liposarcoma (DDLPS), a tumor that lacks effective treatment strategies and is associated with poor outcomes, expresses amplified MDM2 in the presence of wild-type p53. MDM2 ubiquitination of p53 facilitates its XPO1-mediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::513bf5c9f506a9fb4461ff361d314e87
https://doi.org/10.1186/s13046-021-01886-x
https://doi.org/10.1186/s13046-021-01886-x
Autor:
Stefano Percio, Alessandro Cicchetti, Monica Tortoreto, Valentina Zuco, C. Stucchi, Riccardo Valdagni, Nadia Zaffaroni, Paolo Gandellini, Martina Tripari, Valentina Doldi, Rihan El Bezawy, Stella Tinelli
Publikováno v:
Cancers
Volume 12
Issue 6
Cancers, Vol 12, Iss 1462, p 1462 (2020)
Volume 12
Issue 6
Cancers, Vol 12, Iss 1462, p 1462 (2020)
Speckle-type POZ (pox virus and zinc finger protein) protein (SPOP) is the most commonly mutated gene in prostate cancer (PCa). Recent evidence reports a role of SPOP in DNA damage response (DDR), indicating a possible impact of SPOP deregulation on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::112957208663c061d3197dcdcfe38d1e