Bacillus thuringiensis toxins divert progenitor cells toward enteroendocrine fate by decreasing cell adhesion with intestinal stem cells in Drosophila

Autor: Rouba Jneid, Rihab Loudhaief, Nathalie Zucchini-Pascal, Marie-Paule Nawrot-Esposito, Arnaud Fichant, Raphael Rousset, Mathilde Bonis, Dani Osman, Armel Gallet

Publikováno v: eLife, Vol 12 (2023)

Bacillus thuringiensis subsp. kurstaki (Btk) is a strong pathogen toward lepidopteran larvae thanks to specific Cry toxins causing leaky gut phenotypes. Hence, Btk and its toxins are used worldwide as microbial insecticide and in genetically modified

Externí odkaz: https://doaj.org/article/e9759c09f0434a11bc9da1fe4d0604e0

The DH31/CGRP enteroendocrine peptide triggers intestinal contractions favoring the elimination of opportunistic bacteria.

Autor: Olivia Benguettat, Rouba Jneid, Julie Soltys, Rihab Loudhaief, Alexandra Brun-Barale, Dani Osman, Armel Gallet

Publikováno v: PLoS Pathogens, Vol 14, Iss 9, p e1007279 (2018)

The digestive tract is the first organ affected by the ingestion of foodborne bacteria. While commensal bacteria become resident, opportunistic or virulent bacteria are eliminated from the gut by the local innate immune system. Here we characterize a

Externí odkaz: https://doaj.org/article/154cda8f811f491fa900b34507d8318a

Drosophila activins adapt gut size to food intake and promote regenerative growth

Autor: Christian F. Christensen, Quentin Laurichesse, Rihab Loudhaief, Julien Colombani, Ditte S. Andersen

Rapidly renewable tissues adapt different strategies to cope with environmental insults. While tissue repair is associated with increased ISC proliferation and accelerated tissue turnover rates, reduced calorie intake triggers a homeostasis-breaking

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::76162308fb93d8cb9566055e123e77b0
https://doi.org/10.1101/2023.01.26.525639

Drosophila TNFRs Grindelwald and Wengen bind Eiger with different affinities and promote distinct cellular functions

Autor: Vincent Olieric, Valentina Cecatiello, Silvia Monzani, Julien Colombani, Valentina Palmerini, Ditte S. Andersen, Sara Mari, Rihab Loudhaief, Marina Mapelli, Quentin Laurichesse, Sebastiano Pasqualato

Publikováno v: Nature Communications
Palmerini, V, Monzani, S, Laurichesse, Q, Loudhaief, R, Mari, S, Cecatiello, V, Olieric, V, Pasqualato, S, Colombani, J, Andersen, D S & Mapelli, M 2021, ' Drosophila TNFRs Grindelwald and Wengen bind Eiger with different affinities and promote distinct cellular functions ', Nature Communications, vol. 12, 2070 . https://doi.org/10.1038/s41467-021-22080-9
'Nature Communications ', vol: 12, pages: 2070-1-2070-12 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)

The Drosophila tumour necrosis factor (TNF) ligand-receptor system consists of a unique ligand, Eiger (Egr), and two receptors, Grindelwald (Grnd) and Wengen (Wgn), and therefore provides a simple system for exploring the interplay between ligand and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c287e7402c450fb99e08121a0e23be
https://doi.org/10.1038/s41467-021-22080-9

Enteroendocrine Cells, A Potential Way to Control Intestinal Stem Cell Proliferation

Autor: Rihab Loudhaief

Publikováno v: International Journal of Stem cell Research & Therapy. 3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6f02325c93cf6d84a104d5898ee080a5
https://doi.org/10.23937/2469-570x/1410037