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pro vyhledávání: '"Rigo I Acevedo"'
Autor:
Alexander S Carlson, Rigo I Acevedo, Daniel M Lim, Roman Gulati, Agnes Gawne, Alexandra O Sokolova, Heather H Cheng, Peter S Nelson, R Bruce Montgomery, Evan Y Yu, Michael T Schweizer
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0239686 (2020)
IntroductionA significant proportion of patients with metastatic castration-resistant prostate cancer (mCRPC) harbor mutations in homologous recombination (HR) repair genes, with some of these mutations associating with increased tumor susceptibility
Externí odkaz:
https://doaj.org/article/f6c10cf143e14114ba66811e4329fc74
Autor:
Heather H. Cheng, Michael T. Schweizer, Daniel M. Lim, Evan Y. Yu, Rigo I. Acevedo, Agnes M. Gawne, R. Bruce Montgomery, Alexander S. Carlson, Alexandra O. Sokolova, Roman Gulati, Peter S. Nelson
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0239686 (2020)
PLoS ONE
PLoS ONE
IntroductionA significant proportion of patients with metastatic castration-resistant prostate cancer (mCRPC) harbor mutations in homologous recombination (HR) repair genes, with some of these mutations associating with increased tumor susceptibility
Autor:
Rigo I. Acevedo, Daniel M. Lim, Alex S. Carlson, Evan Y. Yu, Michael T. Schweizer, Roman Gulati
Publikováno v:
Journal of Clinical Oncology. 38:172-172
172 Background: Nearly 25% of patients with mCRPC harbor DDR alterations, with some of these mutations associating with increased tumor susceptibility to PARP inhibitors and platinum-based chemotherapies. While, mutations in some DDR genes (e.g. BRCA