Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Rigney E"'
Autor:
Gary KL Chan, Samantha Maisel, Yeonjoo C Hwang, Bryan C Pascual, Rebecca RB Wolber, Phuong Vu, Krushna C Patra, Mehdi Bouhaddou, Heidi L Kenerson, Huat C Lim, Donald Long, Raymond S Yeung, Praveen Sethupathy, Danielle L Swaney, Nevan J Krogan, Rigney E Turnham, Kimberly J Riehle, John D Scott, Nabeel Bardeesy, John D Gordan
Publikováno v:
eLife, Vol 12 (2023)
Genetic alterations that activate protein kinase A (PKA) are found in many tumor types. Yet, their downstream oncogenic signaling mechanisms are poorly understood. We used global phosphoproteomics and kinase activity profiling to map conserved signal
Externí odkaz:
https://doaj.org/article/05fc37cffa674796bf7877b4353fc32a
Autor:
Timothy A. Dinh, Mark L. Jewell, Matt Kanke, Adam Francisco, Ramja Sritharan, Rigney E. Turnham, Seona Lee, Edward R. Kastenhuber, Eliane Wauthier, Cynthia D. Guy, Raymond S. Yeung, Scott W. Lowe, Lola M. Reid, John D. Scott, Anna M. Diehl, Praveen Sethupathy
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 4, Pp 803-817 (2019)
Background & Aims: Fibrolamellar carcinoma (FLC) is a rare liver cancer that primarily affects adolescents and young adults. It is characterized by a heterozygous approximately 400-kb deletion on chromosome 19 that results in a unique fusion between
Externí odkaz:
https://doaj.org/article/7c0b575b397444a8aec84eb5e9313d8a
Autor:
Emily D Crawford, Irene Acosta, Vida Ahyong, Erika C Anderson, Shaun Arevalo, Daniel Asarnow, Shannon Axelrod, Patrick Ayscue, Camillia S Azimi, Caleigh M Azumaya, Stefanie Bachl, Iris Bachmutsky, Aparna Bhaduri, Jeremy Bancroft Brown, Joshua Batson, Astrid Behnert, Ryan M Boileau, Saumya R Bollam, Alain R Bonny, David Booth, Michael Jerico B Borja, David Brown, Bryan Buie, Cassandra E Burnett, Lauren E Byrnes, Katelyn A Cabral, Joana P Cabrera, Saharai Caldera, Gabriela Canales, Gloria R Castañeda, Agnes Protacio Chan, Christopher R Chang, Arthur Charles-Orszag, Carly Cheung, Unseng Chio, Eric D Chow, Y Rose Citron, Allison Cohen, Lillian B Cohn, Charles Chiu, Mitchel A Cole, Daniel N Conrad, Angela Constantino, Andrew Cote, Tre'Jon Crayton-Hall, Spyros Darmanis, Angela M Detweiler, Rebekah L Dial, Shen Dong, Elias M Duarte, David Dynerman, Rebecca Egger, Alison Fanton, Stacey M Frumm, Becky Xu Hua Fu, Valentina E Garcia, Julie Garcia, Christina Gladkova, Miriam Goldman, Rafael Gomez-Sjoberg, M Grace Gordon, James C R Grove, Shweta Gupta, Alexis Haddjeri-Hopkins, Pierce Hadley, John Haliburton, Samantha L Hao, George Hartoularos, Nadia Herrera, Melissa Hilberg, Kit Ying E Ho, Nicholas Hoppe, Shayan Hosseinzadeh, Conor J Howard, Jeffrey A Hussmann, Elizabeth Hwang, Danielle Ingebrigtsen, Julia R Jackson, Ziad M Jowhar, Danielle Kain, James Y S Kim, Amy Kistler, Oriana Kreutzfeld, Jessie Kulsuptrakul, Andrew F Kung, Charles Langelier, Matthew T Laurie, Lena Lee, Kun Leng, Kristoffer E Leon, Manuel D Leonetti, Sophia R Levan, Sam Li, Aileen W Li, Jamin Liu, Heidi S Lubin, Amy Lyden, Jennifer Mann, Sabrina Mann, Gorica Margulis, Diana M Marquez, Bryan P Marsh, Calla Martyn, Elizabeth E McCarthy, Aaron McGeever, Alexander F Merriman, Lauren K Meyer, Steve Miller, Megan K Moore, Cody T Mowery, Tanzila Mukhtar, Lusajo L Mwakibete, Noelle Narez, Norma F Neff, Lindsay A Osso, Diter Oviedo, Suping Peng, Maira Phelps, Kiet Phong, Peter Picard, Lindsey M Pieper, Neha Pincha, Angela Oliveira Pisco, Angela Pogson, Sergei Pourmal, Robert R Puccinelli, Andreas S Puschnik, Elze Rackaityte, Preethi Raghavan, Madhura Raghavan, James Reese, Joseph M Replogle, Hanna Retallack, Helen Reyes, Donald Rose, Marci F Rosenberg, Estella Sanchez-Guerrero, Sydney M Sattler, Laura Savy, Stephanie K See, Kristin K Sellers, Paula Hayakawa Serpa, Maureen Sheehy, Jonathan Sheu, Sukrit Silas, Jessica A Streithorst, Jack Strickland, Doug Stryke, Sara Sunshine, Peter Suslow, Renaldo Sutanto, Serena Tamura, Michelle Tan, Jiongyi Tan, Alice Tang, Cristina M Tato, Jack C Taylor, Iliana Tenvooren, Erin M Thompson, Edward C Thornborrow, Eric Tse, Tony Tung, Marc L Turner, Victoria S Turner, Rigney E Turnham, Mary J Turocy, Trisha V Vaidyanathan, Ilia D Vainchtein, Manu Vanaerschot, Sara E Vazquez, Anica M Wandler, Anne Wapniarski, James T Webber, Zara Y Weinberg, Alexandra Westbrook, Allison W Wong, Emily Wong, Gajus Worthington, Fang Xie, Albert Xu, Terrina Yamamoto, Ying Yang, Fauna Yarza, Yefim Zaltsman, Tina Zheng, Joseph L DeRisi
Publikováno v:
PLoS Pathogens, Vol 16, Iss 10, p e1008966 (2020)
Externí odkaz:
https://doaj.org/article/3bbb68a359bd42bc9db996dc6d89e140
Autor:
Rigney E Turnham, F Donelson Smith, Heidi L Kenerson, Mitchell H Omar, Martin Golkowski, Irvin Garcia, Renay Bauer, Ho-Tak Lau, Kevin M Sullivan, Lorene K Langeberg, Shao-En Ong, Kimberly J Riehle, Raymond S Yeung, John D Scott
Publikováno v:
eLife, Vol 8 (2019)
Fibrolamellar carcinoma (FLC) is a rare liver cancer. FLCs uniquely produce DNAJ-PKAc, a chimeric enzyme consisting of a chaperonin-binding domain fused to the Cα subunit of protein kinase A. Biochemical analyses of clinical samples reveal that a un
Externí odkaz:
https://doaj.org/article/df0373e02b8847ebb7435e13a15b41eb
Autor:
Dinh, Timothy A., Jewell, Mark L., Kanke, Matt, Francisco, Adam, Sritharan, Ramja, Turnham, Rigney E., Lee, Seona, Kastenhuber, Edward R., Wauthier, Eliane, Guy, Cynthia D., Yeung, Raymond S., Lowe, Scott W., Reid, Lola M., Scott, John D., Diehl, Anna M., Sethupathy, Praveen
Publikováno v:
In Cellular and Molecular Gastroenterology and Hepatology 2019 7(4):803-817
Akademický článek
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Autor:
Adriana Pitea, Rigney E Turnham, Manon Eckhardt, Gwendolyn M Jang, Zhong Xu, Huat C Lim, Alex Choi, John Von Dollen, Rebecca S. Levin, James T Webber, Elizabeth McCarthy, Junjie Hu, Xiaolei Li, Li Che, Gary Chan, R. Katie Kelley, Danielle Swaney, Wei Zhang, Sourav Bandyopadhyay, Fabian J Theis, Xin Chen, Kevan Shokat, Trey Ideker, Nevan J Krogan, John D Gordan
SummaryInfection by hepatitis B virus (HBV) increases risk for liver cancer by inducing inflammation, cellular stress and cell death. To elucidate the molecular pathways by which HBV promotes cancer development and progression, we used affinity purif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c06cf8a0185f305c549a512f7867853
https://doi.org/10.1101/2023.03.15.532845
https://doi.org/10.1101/2023.03.15.532845
Autor:
Gary KL Chan, Samantha Maisel, Yeonjoo C Hwang, Bryan C Pascual, Rebecca RB Wolber, Phuong Vu, Krushna C Patra, Mehdi Bouhaddou, Heidi L Kenerson, Huat C Lim, Donald Long, Raymond S Yeung, Praveen Sethupathy, Danielle L Swaney, Nevan J Krogan, Rigney E Turnham, Kimberly J Riehle, John D Scott, Nabeel Bardeesy, John D Gordan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e57702eaa8f41296e52fffc2f1b15a79
https://doi.org/10.7554/elife.69521.sa2
https://doi.org/10.7554/elife.69521.sa2
Autor:
Rigney E Turnham, Huat Chye Lim, Lucille Ferret, Katherine Lo, LeeAnn Wang, Alex Choi, John D Gordan
Publikováno v:
Clinical Cancer Research. 28:PO023-PO023
Although precision medicine has revolutionized the treatment for other solid tumors, comprehensive genome profiling of hepatocellular carcinoma (HCC) has demonstrated that there are few oncogenic mutational drivers. HCC arises nearly universally in t
Autor:
John Gordan, Adriana Pitea, Rigney E Turnham, Manon Eckhardt, Gwendolyn M Jang, Huat Lim, Alex L Choi, Sourav Bandyopadhyay, Danielle Swaney, Kevan Shokat, Trey Ideker, Nevan Krogan
Publikováno v:
Clinical Cancer Research. 28:PO017-PO017
Viral hepatitis promotes hepatocellular carcinoma (HCC) initiation by inducing inflammation, cellular stress and cell death. However, the cell-intrinsic effects of viral infection in advanced HCC remain unclear. We used affinity purification mass spe