Superoxide Dismutase Mimetic GC4419 Enhances the Oxidation of Pharmacological Ascorbate and Its Anticancer Effects in an H₂O₂-Dependent Manner.

Autor: Heer CD; Free Radical and Radiation Biology Program, Department of Radiation Oncology, Holden Comprehensive Cancer Center, The University of Iowa College of Medicine, Iowa City, IA 52242, USA. collin-heer@uiowa.edu., Davis AB; Free Radical and Radiation Biology Program, Department of Radiation Oncology, Holden Comprehensive Cancer Center, The University of Iowa College of Medicine, Iowa City, IA 52242, USA. andrew-davis-2@uiowa.edu., Riffe DB; Free Radical and Radiation Biology Program, Department of Radiation Oncology, Holden Comprehensive Cancer Center, The University of Iowa College of Medicine, Iowa City, IA 52242, USA. david-riffe@uiowa.edu., Wagner BA; Free Radical and Radiation Biology Program, Department of Radiation Oncology, Holden Comprehensive Cancer Center, The University of Iowa College of Medicine, Iowa City, IA 52242, USA. brett-wagner@uiowa.edu., Falls KC; Free Radical and Radiation Biology Program, Department of Radiation Oncology, Holden Comprehensive Cancer Center, The University of Iowa College of Medicine, Iowa City, IA 52242, USA. kelly-falls@uiowa.edu., Allen BG; Free Radical and Radiation Biology Program, Department of Radiation Oncology, Holden Comprehensive Cancer Center, The University of Iowa College of Medicine, Iowa City, IA 52242, USA. bryan-allen@uiowa.edu., Buettner GR; Free Radical and Radiation Biology Program, Department of Radiation Oncology, Holden Comprehensive Cancer Center, The University of Iowa College of Medicine, Iowa City, IA 52242, USA. garry-buettner@uiowa.edu., Beardsley RA; Galera Therapeutics, Malvern, PA 19355, USA. rbeardsley@galeratx.com., Riley DP; Galera Therapeutics, Malvern, PA 19355, USA. driley@galeratx.com., Spitz DR; Free Radical and Radiation Biology Program, Department of Radiation Oncology, Holden Comprehensive Cancer Center, The University of Iowa College of Medicine, Iowa City, IA 52242, USA. douglas-spitz@uiowa.edu.

Publikováno v: Antioxidants (Basel, Switzerland) [Antioxidants (Basel)] 2018 Jan 19; Vol. 7 (1). Date of Electronic Publication: 2018 Jan 19.