Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Rifeng, Gao"'
Autor:
Kun Yang, Yongchao Zhao, Jingjing Hu, Rifeng Gao, Jiaran Shi, Xiang Wei, Juntao Chen, Kai Hu, Aijun Sun, Junbo Ge
Publikováno v:
Journal of Advanced Research, Vol 61, Iss , Pp 193-209 (2024)
Introduction: N6-methyladenosine (m6A) methylation produces a marked effect on cardiovascular diseases. The m6A demethylase AlkB homolog 5 (ALKBH5), as an m6A “eraser”, is responsible for decreased m6A modification. However, its role in cardiac f
Externí odkaz:
https://doaj.org/article/ffc8d5b420d1462da8c4d5ed1fbf2e5a
Autor:
Yiwen Wang, Yang Gao, Huairui Shi, Rifeng Gao, Ji’e Yang, Ya’nan Qu, Shiyu Hu, Jian Zhang, Jingpu Wang, Jiatian Cao, Feng Zhang, Junbo Ge
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Peripheral vascular disease (PVD) is an emerging public health burden with a high rate of disability and mortality. Gasdermin D (GSDMD) has been reported to exert pyroptosis and play a critical role in the pathophysiology of many cardiovascu
Externí odkaz:
https://doaj.org/article/d6a671c207674e618df9b72933a1a6da
Autor:
Yijing Lu, Wenlong Yang, Zhiyong Qi, Rifeng Gao, Jing Tong, Tingwen Gao, Yin Zhang, Aijun Sun, Shuning Zhang, Junbo Ge
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/e4afd954f45c42489c282436d4e3cf48
Autor:
Jiahui Cheng, Yiming Zhang, Liang Ma, Wenxian Du, Qiang Zhang, Rifeng Gao, Xinxin Zhao, Yujie Chen, Lixian Jiang, Xiaoyang Li, Bo Li, Yan Zhou
Publikováno v:
Advanced Science, Vol 10, Iss 33, Pp n/a-n/a (2023)
Abstract Ulcerative colitis (UC) is a chronic inflammatory bowel disease mainly involving the colon and rectum, which features recurrent mucosal inflammation. The excessive production of reactive oxygen species (ROS) is a trigger for pathological cha
Externí odkaz:
https://doaj.org/article/48d70083f1a1497cb98646a789a1c15d
Autor:
Peng Wang, Rifeng Gao, Tingting Wu, Jinyan Zhang, Xiaolei Sun, Fan Fan, Cong Wang, Sanli Qian, Bingyu Li, Yunzeng Zou, Yuqing Huo, John Fassett, Yingjie Chen, Junbo Ge, Aijun Sun
Publikováno v:
Redox Biology, Vol 67, Iss , Pp 102884- (2023)
Adenosine kinase (ADK) plays the major role in cardiac adenosine metabolism, so that inhibition of ADK increases myocardial adenosine levels. While the cardioprotective actions of extracellular adenosine against ischemia/reperfusion (I/R) are well-es
Externí odkaz:
https://doaj.org/article/934b8c99c2984fd6973e193d027afd62
Autor:
Xiaolei Sun, Hang Chen, Rifeng Gao, Ya Huang, Yanan Qu, Heng Yang, Xiang Wei, Shiyu Hu, Jian Zhang, Peng Wang, Yunzeng Zou, Kai Hu, Junbo Ge, Aijun Sun
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107790- (2023)
Summary: Doxorubicin is a wildly used effective anticancer agent. However, doxorubicin use is also related to cardiotoxic side effect in some patients. Mitochondrial damage has been shown to be one of the pathogeneses of doxorubicin-induced myocardia
Externí odkaz:
https://doaj.org/article/e28b700743284e418b61a0ab74d314e5
Autor:
Juntao Chen, Cuidi Xu, Kun Yang, Rifeng Gao, Yirui Cao, Lifei Liang, Siyue Chen, Shihao Xu, Ruiming Rong, Jina Wang, Tongyu Zhu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
m6A modification has been reported to play roles in many developmental and pathological processes, but its role in AKI remains poorly understood. Here, the authors show the role and the mechanism of the m6A demethylase, ALKBH5 on IRI induced AKI.
Externí odkaz:
https://doaj.org/article/ac2ae51bb26446b2ad18b825295ea9ef
Autor:
Ya’nan Qu, Rifeng Gao, Xiang Wei, Xiaolei Sun, Kun Yang, Huairui Shi, Yang Gao, Shiyu Hu, Yiwen Wang, Ji’e Yang, Aijun Sun, Feng Zhang, Junbo Ge
Publikováno v:
Cell Death and Disease, Vol 13, Iss 10, Pp 1-14 (2022)
Abstract Cardiomyocyte pyroptosis and apoptosis play a vital role in the pathophysiology of several cardiovascular diseases. Our recent study revealed that gasdermin D (GSDMD) can promote myocardial I/R injury via the caspase-11/GSDMD pathway. We als
Externí odkaz:
https://doaj.org/article/01b10e0a6b924fabb7ea6abb43f8cd0b
Autor:
Xiaolei Sun, Rifeng Gao, Wenjia Li, Yongchao Zhao, Heng Yang, Hang Chen, Hao Jiang, Zhen Dong, Jingjing Hu, Jin Liu, Yunzeng Zou, Aijun Sun, Junbo Ge
Publikováno v:
Bioactive Materials, Vol 6, Iss 7, Pp 2058-2069 (2021)
Mitochondrial damage is a critical driver in myocardial ischemia-reperfusion (I/R) injury and can be alleviated via the mitochondrial transplantation. The efficiency of mitochondrial transplantation is determined by mitochondrial vitality. Because al
Externí odkaz:
https://doaj.org/article/10f669e72f7649d895a9cbc2d30b218f
Autor:
Ya’nan Qu, Rifeng Gao, Xiang Wei, Xiaolei Sun, Kun Yang, Huairui Shi, Yang Gao, Shiyu Hu, Yiwen Wang, Ji’e Yang, Aijun Sun, Feng Zhang, Junbo Ge
Publikováno v:
Cell Death and Disease, Vol 13, Iss 11, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/75cfdf8be7e948f693af9aa598af813b