Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Rifat Hasina"'
Autor:
Manijeh Goldberg, Aaron Manzi, Peter Conway, Stefanie Cantin, Vasudha Mishra, Alka Singh, Alexander T. Pearson, Eric R. Goldberg, Sam Goldberger, Benjamin Flaum, Rifat Hasina, Nyall R. London, Gary L. Gallia, Chetan Bettegowda, Sonya E. O’Neill, Erkin Aydin, Alex Zhavoronkov, Anxo Vidal, Atenea Soto, Maria Jose Alonso, Ari J. Rosenberg, Mark W. Lingen, Anil D’Cruz, Nishant Agrawal, Evgeny Izumchenko
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Cisplatin is the most frequently used chemotherapeutic agent for the treatment of patients with oral cavity squamous cell carcinoma (OCSCC), however, systemic administration is often associated with dose limiting side effects. Here the authors design
Externí odkaz:
https://doaj.org/article/d8848b4e41784c8c9643d35f80e0a0c7
Autor:
Manijeh Goldberg, Aaron Manzi, Amritpreet Birdi, Brandon Laporte, Peter Conway, Stefanie Cantin, Vasudha Mishra, Alka Singh, Alexander T. Pearson, Eric R. Goldberg, Sam Goldberger, Benjamin Flaum, Rifat Hasina, Nyall R. London, Gary L. Gallia, Chetan Bettegowda, Simon Young, Vlad Sandulache, James Melville, Jonathan Shun, Sonya E. O’Neill, Erkin Aydin, Alex Zhavoronkov, Anxo Vidal, Atenea Soto, Maria Jose Alonso, Ari J. Rosenberg, Mark W. Lingen, Anil D’Cruz, Nishant Agrawal, Evgeny Izumchenko
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/1fc932e1d18f416da778b225b7831ccf
MET and PI3K/mTOR as a potential combinatorial therapeutic target in malignant pleural mesothelioma.
Autor:
Rajani Kanteti, Immanuel Dhanasingh, Ichiro Kawada, Frances E Lennon, Qudsia Arif, Raphael Bueno, Rifat Hasina, Aliya N Husain, Wickii Vigneswaran, Tanguy Seiwert, Hedy L Kindler, Ravi Salgia
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e105919 (2014)
Malignant pleural mesothelioma (MPM) is an aggressive disease with a poor prognosis. Studies have shown that both MET and its key downstream intracellular signaling partners, PI3K and mTOR, are overexpressed in MPM. Here we determined the combinatori
Externí odkaz:
https://doaj.org/article/d1caa3a63c8b473fa72f24f985776b73
Autor:
Benjamin D Ferguson, Ren Liu, Cleo E Rolle, Yi-Hung Carol Tan, Valery Krasnoperov, Rajani Kanteti, Maria S Tretiakova, Gustavo M Cervantes, Rifat Hasina, Robyn D Hseu, A John Iafrate, Theodore Karrison, Mark K Ferguson, Aliya N Husain, Leonardo Faoro, Everett E Vokes, Parkash S Gill, Ravi Salgia
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e67668 (2013)
Despite progress in locoregional and systemic therapies, patient survival from lung cancer remains a challenge. Receptor tyrosine kinases are frequently implicated in lung cancer pathogenesis, and some tyrosine kinase inhibition strategies have been
Externí odkaz:
https://doaj.org/article/49dc221d374e40ea970d698d828f4a91
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 3 (2011)
Hepatocyte growth factor receptor (HGFR), the product of the MET gene, plays an important role in normal cellular function and oncogenesis. In cancer, HGFR has been implicated in cellular proliferation, cell survival, invasion, cell motility, metasta
Externí odkaz:
https://doaj.org/article/1fc9890c9abe47dc9a1ef7642c717775
Autor:
Yi-Hung Carol Tan, Soundararajan Krishnaswamy, Suvobroto Nandi, Rajani Kanteti, Sapana Vora, Kenan Onel, Rifat Hasina, Fang-Yi Lo, Essam El-Hashani, Gustavo Cervantes, Matthew Robinson, Han-Shui Hsu, Stephen C. Kales, Stanley Lipkowitz, Theodore Karrison, Martin Sattler, Everett E. Vokes, Yi-Ching Wang, Ravi Salgia
Publikováno v:
PLoS ONE, Vol 6, Iss 1 (2011)
Externí odkaz:
https://doaj.org/article/0a17a2ae529f44f28ddc25cc8756dc0e
Autor:
Younghee Lee, Xinan Yang, Yong Huang, Hanli Fan, Qingbei Zhang, Youngfei Wu, Jianrong Li, Rifat Hasina, Chao Cheng, Mark W Lingen, Mark B Gerstein, Ralph R Weichselbaum, H Rosie Xing, Yves A Lussier
Publikováno v:
PLoS Computational Biology, Vol 6, Iss 4, p e1000730 (2010)
Due to the large number of putative microRNA gene targets predicted by sequence-alignment databases and the relative low accuracy of such predictions which are conducted independently of biological context by design, systematic experimental identific
Externí odkaz:
https://doaj.org/article/1f3f6d79c24448c498154cf3417eabdd
Autor:
Yi-Hung Carol Tan, Soundararajan Krishnaswamy, Suvobroto Nandi, Rajani Kanteti, Sapana Vora, Kenan Onel, Rifat Hasina, Fang-Yi Lo, Essam El-Hashani, Gustavo Cervantes, Matthew Robinson, Han-Shui Hsu, Stephen C Kales, Stanley Lipkowitz, Theodore Karrison, Martin Sattler, Everett E Vokes, Yi-Ching Wang, Ravi Salgia
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8972 (2010)
Non-small cell lung cancer (NSCLC) is a heterogeneous group of disorders with a number of genetic and proteomic alterations. c-CBL is an E3 ubiquitin ligase and adaptor molecule important in normal homeostasis and cancer. We determined the genetic va
Externí odkaz:
https://doaj.org/article/07bc66ce343e48fc911cf1cc1edddb67
Autor:
Kenneth Yan, Samuel Auger, Ashley Diaz, Julia Naman, Ramya Vemulapalli, Rifat Hasina, Evgeny Izumchenko, Benjamin Shogan, Nishant Agrawal
Publikováno v:
Otolaryngol Head Neck Surg
OBJECTIVE. To examine the oral microbiome in the context of oral cavity squamous cell carcinoma. STUDY DESIGN. Basic science research. SETTING. Academic medical center. METHODS. Oral swabs were collected from patients presenting to the operating room
Autor:
Ravi Salgia, Everett E. Vokes, Aliya N. Husain, Erin Smithberger, Jeffrey Mueller, Qudsia Arif, Rifat Hasina, Ichiro Kawada
PDF file - 124K, Figure S2. Sub-network 'Calmodulin, c-Cbl, MET, PI3K reg class IA (p85), PDGF-R-beta' of Mitogenic signaling (Supplementary Table S1 No.1). Sub-network is made using 'Analyze network, Build Network' of GeneGo from the significant gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a72ddd7a9140862a9c2b3cd03c00dec
https://doi.org/10.1158/0008-5472.22402428
https://doi.org/10.1158/0008-5472.22402428