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pro vyhledávání: '"Rifah Gheyas"'
The involvement of caspases in the process of nuclear removal during lens fiber cell differentiation
Autor:
Rifah Gheyas, A. Sue Menko
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-12 (2023)
Abstract The terminal differentiation of lens fiber cells involves elimination of their organelles, which must occur while still maintaining their functionality throughout a lifetime. Removal of non-nuclear organelles is accomplished through inductio
Externí odkaz:
https://doaj.org/article/fcde7c42fd6c474b9a3a6c59a44609ce
Autor:
Rifah Gheyas, A. Sue Menko
Publikováno v:
STAR Protocols, Vol 4, Iss 4, Pp 102569- (2023)
Summary: The elimination of lens organelles during development, required for mature lens function, is an autophagy-dependent mechanism induced through suppression of PI3K signaling. Here, we present a protocol for investigating the signaling pathways
Externí odkaz:
https://doaj.org/article/22cb0e13cda0453ba3333fb6f1828e60
Autor:
Marc Kantorow, A. Sue Menko, Daniel Chauss, Joshua Disatham, Rifah Gheyas, Lisa A. Brennan, Lauren Daley, David Blanco
Publikováno v:
Developmental Biology. 453:86-104
Changes in chromatin accessibility regulate the expression of multiple genes by controlling transcription factor access to key gene regulatory sequences. Here, we sought to establish a potential function for altered chromatin accessibility in control
Publikováno v:
Exp Cell Res
The terminal steps of lens cell differentiation require elimination of all organelles to create a central Organelle Free Zone (OFZ) that is required for lens function of focusing images on the retina. Previous studies show that the spatiotemporal eli