Zobrazeno 1 - 10
of 273
pro vyhledávání: '"Rifaat, Safadi"'
Weaker SARS-CoV-2 vaccine responses in nonalcoholic fatty liver disease with advanced liver fibrosis
Autor:
David Hakimian, Johnny Amer, Alaa Jammal, Asher Shafrir, Yael Milgrom, Mohammad Masarowah, Wadi Hazou, Yuval Ishay, Ashraf Imam, Adi Francis, Abed Khalaileh, Rifaat Safadi
Publikováno v:
Vaccine: X, Vol 15, Iss , Pp 100359- (2023)
Background: SARS-CoV-2 vaccine responses that could harbor potential risks to chronic liver diseased patients. Aims: To assess immune response following Pfizer's SARS-CoV-2 vaccine in patients with different liver fibrosis severities of nonalcoholic
Externí odkaz:
https://doaj.org/article/af4b55d4ed4142b8ae2d7851c624af9a
Autor:
Asher Shafrir, Lior H. Katz, Michal Shauly-Aharonov, Adar Zinger, Rifaat Safadi, Joshua Stokar, Itay Kalisky
Publikováno v:
Journal of Clinical Medicine, Vol 13, Iss 7, p 1869 (2024)
Background: Sarcopenia is underdiagnosed in patients with inflammatory bowel disease (IBD). Low alanine transaminase (ALT) is associated with sarcopenia. We evaluated the association between low ALT and the presence of IBD and disease activity. Metho
Externí odkaz:
https://doaj.org/article/adb7fadd1e114dc79984b8243604f346
Autor:
Dor Genzel, Lior H. Katz, Rifaat Safadi, Aliza Rozenberg, Yael Milgrom, Jeremy M. Jacobs, Asher Shafrir
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
IntroductionFrailty is a known risk factor for many diseases, including COVID-19. However, many frail patients are undiagnosed as the diagnosis can be cumbersome. Alanine transaminase (ALT) is found not only in the liver but also in the muscle tissue
Externí odkaz:
https://doaj.org/article/f78ab6d167da4a7ba3e8864191409ea7
Autor:
Raanan Greenman, Michal Segal-Salto, Neta Barashi, Ophir Hay, Avi Katav, Omer Levi, Ilan Vaknin, Revital Aricha, Sarit Aharoni, Tom Snir, Inbal Mishalian, Devorah Olam, Johnny Amer, Ahmad Salhab, Rifaat Safadi, Yaakov Maor, Palak Trivedi, Christopher J. Weston, Francesca Saffioti, Andrew Hall, Massimo Pinzani, Douglas Thorburn, Amnon Peled, Adi Mor
Publikováno v:
JCI Insight, Vol 8, Iss 12 (2023)
ˆCCL24 is a pro-fibrotic, pro-inflammatory chemokine expressed in several chronic fibrotic diseases. In the liver, CCL24 plays a role in fibrosis and inflammation, and blocking CCL24 led to reduced liver injury in experimental models. We studied the
Externí odkaz:
https://doaj.org/article/db72715b10e74e2cbaca199c73a4f4ca
Autor:
Rifaat Safadi, Robert S. Rahimi, Dominique Thabut, Jasmohan S. Bajaj, Kalyan Ram Bhamidimarri, Nikolaos Pyrsopoulos, Amy Potthoff, Stan Bukofzer, Laurene Wang, Khurram Jamil, Krishna R. Devarakonda
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 6, Pp 1449-1459 (2022)
Abstract Hepatic encephalopathy (HE) is a serious neurocognitive complication of liver dysfunction, often associated with elevated plasma ammonia. Ornithine phenylacetate (OP), a potent ammonia scavenger, is being evaluated for the treatment of acute
Externí odkaz:
https://doaj.org/article/ff689e405f304fab928a09f3645c2316
Autor:
Asher Shafrir, Johnny Amer, David Hakimian, Yael Milgrom, Muhammad Massarwa, Wadi Hazou, Ashraf Imam, Abed Khalaileh, Rifaat Safadi
Publikováno v:
Hepatology Communications, Vol 6, Iss 6, Pp 1278-1288 (2022)
The Pfizer‐BioNTech coronavirus disease 2019 (COVID‐19) vaccine has been offered to nonallergic ≥16‐year‐old Israeli adults since December 19, 2020. Data regarding factors associated with vaccine ineffectiveness are limited. The aim of this
Externí odkaz:
https://doaj.org/article/cd9a690df7864ba9997fbbefd41c1d36
Autor:
Abed Khalaileh, Ashraf Imam, Alaa Jammal, David Hakimian, Johnny Amer, Asher Shafrir, Yael Milgrom, Muhammad Massarwa, Wadi Hazou, Majd Khader, Rifaat Safadi
Publikováno v:
Hepatology Communications, Vol 7, Iss 2, Pp e0025-e0025 (2023)
Background and Aims:. We retrospectively assessed the clinical Pfizer’s mRNA SARS-CoV-2 BNT162b2 vaccination outcomes and the serologic impact on liver transplant (LT) recipients. Patients and Methods:. One hundred and sixty-seven LT cases followed
Externí odkaz:
https://doaj.org/article/020387f3a17a42739f439edb3b27ebdf
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/7eaf6cae25c240b5b44c224b0aee7cce
Autor:
Ting Zhang, Xinrui Yang, Wanping Xu, Jing Wang, Dawei Wu, Zhixian Hong, Shengxian Yuan, Zhen Zeng, Xiaodong Jia, Shanshan Lu, Rifaat Safadi, Sen Han, Zhihong Yang, Leonard M. Neckers, Suthat Liangpunsakul, Weiping Zhou, Yinying Lu
Publikováno v:
Cancer Biology & Medicine, Vol 18, Iss 3, Pp 693-704 (2021)
Objective: Hepatocellular carcinoma (HCC), the main type of liver cancer, has a high morbidity and mortality, and a poor prognosis. RNA helicase DDX5, which acts as a transcriptional co-regulator, is overexpressed in most malignant tumors and promote
Externí odkaz:
https://doaj.org/article/984ca1114e1647d6ba9af5a5f0dd2cc7
Publikováno v:
Medicina, Vol 59, Iss 5, p 983 (2023)
Background and Objectives: The neutrophilic peptide, alpha-defensin, is considered an evolving risk factor intimately linked with lipid mobilization. It was previously linked to augmented liver fibrosis. Here, we assess a potential association betwee
Externí odkaz:
https://doaj.org/article/d061968efaca4d9a8f224b2469f0e321