Towards optimization of dexamethasone therapy in the maintenance phase of pediatric acute lymphoblastic leukemia: A population pharmacokinetic and pharmacodynamic study of dexamethasone and metabolite.

Autor: Li L; Department of Hospital Pharmacy, Erasmus University Medical Center, Rotterdam, The Netherlands. Electronic address: l.li.1@erasmusmc.nl., van Hulst AM; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Verwaaijen EJ; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., van den Heuvel-Eibrink MM; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands; Child Health, UMCU-Wilhelmina Children's Hospital, Utrecht, The Netherlands., van den Akker ELTE; Department of Pediatric Endocrinology, Erasmus MC- Sophia Children's Hospital, Rotterdam, The Netherlands., Rietdijk WWJR; Department of Hospital Pharmacy, Erasmus University Medical Center, Rotterdam, The Netherlands., Koch BCPB; Department of Hospital Pharmacy, Erasmus University Medical Center, Rotterdam, The Netherlands., Sassen SDTS; Department of Hospital Pharmacy, Erasmus University Medical Center, Rotterdam, The Netherlands.

Publikováno v: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2024 Nov 17; Vol. 204, pp. 106964. Date of Electronic Publication: 2024 Nov 17.