Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Rienk Pijpstra"'
Population pharmacokinetics of recombinant human C1 inhibitor in patients with hereditary angioedema
Autor:
Edwin S. van Amersfoort, Colm Farrell, Siobhan Hayes, Rienk Pijpstra, Anurag Relan, C. Erik Hack
Publikováno v:
British Journal of Clinical Pharmacology. 76:897-907
Aims To characterize the pharmacokinetics (PK) of recombinant human C1 inhibitor (rhC1INH) in healthy volunteers and hereditary angioedema (HAE) patients. Methods Plasma levels of C1INH following 294 administrations of rhC1INH in 133 subjects were fi
Autor:
C. Erik Hack, Rienk Pijpstra, Beatrijs Oortwijn, Serge A. Versteeg, Aartie Baboeram, Anurag Relan, Ronald van Ree
Publikováno v:
Clinical drug investigation, 33(4), 275-281. Adis International Ltd
Recombinant human C1-inhibitor (rhC1INH) purified from milk of transgenic rabbits is used for the treatment of acute attacks in patients with hereditary angioedema (HAE) due to C1-inhibitor (C1INH) deficiency. The objective was to investigate the ris
Population pharmacokinetics of recombinant human C1 inhibitor in patients with hereditary angioedema
Autor:
Colm, Farrell, Siobhan, Hayes, Anurag, Relan, Edwin S, van Amersfoort, Rienk, Pijpstra, C Erik, Hack
Publikováno v:
British journal of clinical pharmacology. 76(6)
To characterize the pharmacokinetics (PK) of recombinant human C1 inhibitor (rhC1INH) in healthy volunteers and hereditary angioedema (HAE) patients.Plasma levels of C1INH following 294 administrations of rhC1INH in 133 subjects were fitted using non
Publikováno v:
The World Allergy Organization Journal
Background Recombinant C1 inhibitor (rhC1INH) is a novel therapeutic option for the treatment of acute angioedema attacks in patients with hereditary angioedema (HAE). The amino acid sequence of rhC1INH is identical to that of endogenous C1INH. Howev