CRISPR-enabled point-of-care genotyping for APOL1 genetic risk assessment.

Autor: Greensmith R; Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.; Department of Nephrology and Medical Intensive Care, Charité Universitätsmedizin Berlin, Berlin, Germany., Lape IT; Center for Transplantation Sciences, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA., Riella CV; Nephrology Division, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA.; Harvard Medical School, Boston, MA, 02115, USA., Schubert AJ; Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.; Department of Nephrology and Medical Intensive Care, Charité Universitätsmedizin Berlin, Berlin, Germany.; Berlin Institute of Health, Berlin, Germany., Metzger JJ; Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany., Dighe AS; Harvard Medical School, Boston, MA, 02115, USA.; Department of Pathology, Massachusetts General Hospital, Boston, MA, USA., Tan X; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA.; Division of Gastroenterology, Massachusetts General Hospital, Boston, MA, USA.; Institute for Medical Engineering and Science and Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Hemmer B; Department of Neurology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany., Rau J; Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany., Wendlinger S; Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.; Department of Nephrology and Medical Intensive Care, Charité Universitätsmedizin Berlin, Berlin, Germany., Diederich N; Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.; Department of Nephrology and Medical Intensive Care, Charité Universitätsmedizin Berlin, Berlin, Germany., Schütz A; Protein Production & Characterization, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, 13125, Berlin, Germany., Riella LV; Center for Transplantation Sciences, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA. lriella@mgh.harvard.edu.; Department of Surgery, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA. lriella@mgh.harvard.edu.; Division of Nephrology, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA. lriella@mgh.harvard.edu., Kaminski MM; Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany. michael.kaminski@mdc-berlin.de.; Department of Nephrology and Medical Intensive Care, Charité Universitätsmedizin Berlin, Berlin, Germany. michael.kaminski@mdc-berlin.de.; Berlin Institute of Health, Berlin, Germany. michael.kaminski@mdc-berlin.de.

Publikováno v: EMBO molecular medicine [EMBO Mol Med] 2024 Oct; Vol. 16 (10), pp. 2619-2637. Date of Electronic Publication: 2024 Sep 13.

A pragmatic approach to selective genetic testing in kidney transplant candidates.

Autor: Nissaisorakarn P; Division of Nephrology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States., Fadakar PK; Division of Nephrology, Department of Pediatrics, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States., Safa K; Division of Nephrology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States., Lundquist AL; Division of Nephrology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States., Riella CV; Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States., Riella LV; Division of Nephrology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.; Center for Transplantation Sciences, Department of Surgery Massachusetts General Hospital, Boston, MA, United States.

Publikováno v: Frontiers in transplantation [Front Transplant] 2024 Jan 16; Vol. 2, pp. 1342471. Date of Electronic Publication: 2024 Jan 16 (Print Publication: 2023).

ADAR regulates APOL1 via A-to-I RNA editing by inhibition of MDA5 activation in a paradoxical biological circuit.

Autor: Riella CV; Nephrology Division, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215.; Department of Medicinie, Harvard Medical School, Boston, MA 02115., McNulty M; Division of Pediatric Nephrology, Boston Children's Hospital, Boston, MA 02215.; Broad Institute of MIT and Harvard, Cambridge, MA 02142., Ribas GT; Professional and Technological Education Sector, Federal University of Paraná, Curitiba 80060-000, Brazil.; Massachusetts General Hospital, Boston, MA 02114., Tattersfield CF; Nephrology Division, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215., Perez-Gill C; Nephrology Division, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215., Eichinger F; Michigan Kidney Translational Medical Core, University of Michigan, Ann Arbor, MI 48105-5714., Kelly J; Nephrology Division, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215., Chun J; Department of Medicine, University of Calgary, Calgary, AB T2N 1N4, Canada.; Department of Medicine, Snyder Institute for Chronic Diseases, Calgary, AB T2N 1N4, Canada., Subramanian B; Nephrology Division, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215.; Department of Medicinie, Harvard Medical School, Boston, MA 02115., Guizelini D; Professional and Technological Education Sector, Federal University of Paraná, Curitiba 80060-000, Brazil., Alper SL; Nephrology Division, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215.; Department of Medicinie, Harvard Medical School, Boston, MA 02115.; Broad Institute of MIT and Harvard, Cambridge, MA 02142., Pollak MR; Nephrology Division, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215.; Department of Medicinie, Harvard Medical School, Boston, MA 02115.; Broad Institute of MIT and Harvard, Cambridge, MA 02142., Sampson MG; Department of Medicinie, Harvard Medical School, Boston, MA 02115.; Division of Pediatric Nephrology, Boston Children's Hospital, Boston, MA 02215.; Broad Institute of MIT and Harvard, Cambridge, MA 02142., Friedman DJ; Nephrology Division, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215.; Department of Medicinie, Harvard Medical School, Boston, MA 02115.; Broad Institute of MIT and Harvard, Cambridge, MA 02142.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Nov; Vol. 119 (44), pp. e2210150119. Date of Electronic Publication: 2022 Oct 25.

Corrigendum: Immunological Impact of a Gluten-Free Dairy-Free Diet in Children With Kidney Disease: A Feasibility Study.

Autor: Pérez-Sáez MJ; Renal Division, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, United States.; Servicio de Nefrología, Hospital del Mar, Barcelona, Spain., Uffing A; Renal Division, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, United States., Leon J; Renal Division, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, United States., Murakami N; Renal Division, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, United States., Watanabe A; Department of Pediatrics, Pediatric Nephrology Unit, Instituto da Criança, Hospital das Clínicas - University of São Paulo Medical School (USP), São Paulo, Brazil., Borges TJ; Renal Division, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, United States.; Center for Transplantation Sciences, Department of Surgery, Massachusetts General Hospital, Boston, MA, United States., Sabbisetti VS; Renal Division, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, United States., Cureton P; Center for Celiac Research and Treatment, Massachusetts General Hospital for Children, Harvard Medical School, Boston, MA, United States., Kenyon V; Center for Celiac Research and Treatment, Massachusetts General Hospital for Children, Harvard Medical School, Boston, MA, United States., Keating L; Experimental Therapeutics/Interventional Trials Center, Boston Children's Hospital, Boston, MA, United States., Yee K; Center for Clinical Investigation, Brigham & Women's Hospital, Boston, MA, United States., Fernandes Satiro CA; Division of Nutrition, Instituto da Criança, Hospital das Clínicas - University of Sao Paulo Medical School, Sao Paulo, Brazil., Serena G; Center for Celiac Research and Treatment, Massachusetts General Hospital for Children, Harvard Medical School, Boston, MA, United States., Hildebrandt F; Department of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States., Riella CV; Renal Division, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States., Libermann TA; Beth Israel Deaconess Medical Center Genomics, Proteomics, Bioinformatics and Systems Biology Center, Division of Interdisciplinary Medicine and Biotechnology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States., Wang M; Medical and Population Genetics Program, Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, United States., Pascual J; Servicio de Nefrología, Hospital del Mar, Barcelona, Spain., Bonventre JV; Renal Division, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, United States., Cravedi P; Renal Division, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Fasano A; Center for Celiac Research and Treatment, Massachusetts General Hospital for Children, Harvard Medical School, Boston, MA, United States., Riella LV; Renal Division, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, United States.; Center for Transplantation Sciences, Department of Surgery, Massachusetts General Hospital, Boston, MA, United States.; Division of Nephrology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.

Publikováno v: Frontiers in immunology [Front Immunol] 2021 Nov 02; Vol. 12, pp. 798560. Date of Electronic Publication: 2021 Nov 02 (Print Publication: 2021).

Small non-coding RNAs: from trash to treasure.

Autor: Riella CV; Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States.

Publikováno v: Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia [J Bras Nefrol] 2019 Jul 10; Vol. 41 (2), pp. 168-169. Date of Electronic Publication: 2019 Jul 10.