Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Rieko Shioya"'
Publikováno v:
Tetrahedron: Asymmetry. 10:4831-4840
1-Mesitylethylamine was designed as a new non-natural chiral auxiliary. Racemic 1-mesitylethylamine could be synthesized in two steps from mesityl cyanide and could be resolved via separation of diastereomeric carbamates derived from (−)-menthyl ch
Publikováno v:
Chemical and Pharmaceutical Bulletin. 53:638-640
For the construction of new combinatorial libraries, a lead compound was created by replacing the core structure of a hit compound discovered by screening for cytotoxic agents against a tumorigenic cell line. The newly designed compound maintained bi
Publikováno v:
ChemInform. 31
1-Mesitylethylamine was designed as a new non-natural chiral auxiliary. Racemic 1-mesitylethylamine could be synthesized in two steps from mesityl cyanide and could be resolved via separation of diastereomeric carbamates derived from (−)-menthyl ch
Autor:
Ichiro Hayakawa, Shunji Naruto, Yuichi Sugano, Rieko Shioya, Hidehiko Furukawa, Toshinori Agatsuma
Publikováno v:
ChemInform. 35
As a result of a hit-to-lead program using a technique of solution-phase parallel synthesis, a highly potent (2,4-dimethoxyphenyl)-[6-(3-fluorophenyl)-4-hydroxy-3-methylbenzofuran-2-yl]methanone (15b) was synthesized as an optimized derivative of 4-h
Publikováno v:
ChemInform. 35
(3-Amino-6-thiophen-2-yl-thieno[2,3-b]pyridin-2-yl)phenylmethanone (3) was discovered as a new type of cytotoxic agent selective against a tumorigenic cell line. The molecular structure of a previously reported compound, (4-hydroxy-3-methyl-6-phenylb
Autor:
Ichiro Hayakawa, Toshinori Agatsuma, Yuichi Sugano, Hidehiko Furukawa, Shunji Naruto, Rieko Shioya
Publikováno v:
ChemInform. 35
Based on the structure of 4-hydroxy-3-methyl-6-phenylbenzofuran-2-carboxylic acid ethyl ester (1), which exhibits selective cytotoxicity against a tumorigenic cell line, (2,4-dimethoxyphenyl)-(4-hydroxy-3-methyl-6-phenylbenzofuran-2-yl)-methanone (18