Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Rieko Ajima"'
Autor:
Wataru Masuda, Tomoko Yamakawa, Rieko Ajima, Katsuya Miyake, Toshifumi Umemiya, Kazuhiko Azuma, Jun-ichi Tamaru, Makoto Kiso, Puspa Das, Yumiko Saga, Kenji Matsuno, Motoo Kitagawa
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Notch signaling is an evolutionarily conserved mechanism required for numerous types of cell fate decisions in metazoans. It mediates short-range communication between cells with receptors and ligands, both of which are expressed on the cell
Externí odkaz:
https://doaj.org/article/db8e41c628a4412e85d3d2da141b5a7e
Autor:
Piu Banerjee, Fumi Kubo, Hirofumi Nakaoka, Rieko Ajima, Takuya Sato, Tatsumi Hirata, Takuji Iwasato
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Spontaneous activity during the early postnatal period is thought to be crucial for the establishment of mature neural circuits. It remains unclear if the peripheral structure of the developing somatosensory system exhibits spontaneous activ
Externí odkaz:
https://doaj.org/article/8e70074f19bb4bcc88f1b72f580db491
Publikováno v:
PLoS Genetics, Vol 18, Iss 10 (2022)
The evolutionarily conserved RNA helicase DDX6 is a central player in post-transcriptional regulation, but its role during embryogenesis remains elusive. We here show that DDX6 enables proper cell lineage specification from pluripotent cells by analy
Externí odkaz:
https://doaj.org/article/0ac4b33ece0d41ee87ae8a14e6b4aaee
Autor:
Aisha Yesbolatova, Yuichiro Saito, Naomi Kitamoto, Hatsune Makino-Itou, Rieko Ajima, Risako Nakano, Hirofumi Nakaoka, Kosuke Fukui, Kanae Gamo, Yusuke Tominari, Haruki Takeuchi, Yumiko Saga, Ken-ichiro Hayashi, Masato T. Kanemaki
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Auxin-inducible degron systems can be leaky and require high doses of auxin. Here the authors establish AID2 which uses an OsTIR1 mutant and the ligand 5-Ph-IAA to overcome these problems and establish AID-mediated target depletion in mice.
Externí odkaz:
https://doaj.org/article/e96ad288aa7749f7bdb3f1e9cc207dea
Autor:
Masa-Aki Nakaya, Kristibjorn Orri Gudmundsson, Yuko Komiya, Jonathan R Keller, Raymond Habas, Terry P Yamaguchi, Rieko Ajima
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0232025 (2020)
The actin cytoskeleton plays a central role in establishing cell polarity and shape during embryonic morphogenesis. Daam1, a member of the Formin family of actin cytoskeleton regulators, is a Dvl2-binding protein that functions in the Wnt/Planar Cell
Externí odkaz:
https://doaj.org/article/f4c22a5cdb07467a95dc308dbc4b34b0
Publikováno v:
eLife, Vol 7 (2018)
The metameric structure in vertebrates is based on the periodic formation of somites from the anterior end of the presomitic mesoderm (PSM). The segmentation boundary is defined by the Tbx6 expression domain, whose anterior limit is determined by Tbx
Externí odkaz:
https://doaj.org/article/7234894fa3574d6c81306cdbe4b71e77
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187248 (2017)
The segmental pattern of the vertebrate body is established via the periodic formation of somites from the presomitic mesoderm (PSM). This periodical process is controlled by the cyclic and synchronized activation of Notch signaling in the PSM. Prote
Externí odkaz:
https://doaj.org/article/66162cb63b814e83b98a2943057a941e
Autor:
Jeeyeon Cha, Amanda Bartos, Craig Park, Xiaofei Sun, Yingju Li, Sang-Wook Cha, Rieko Ajima, Hsin-Yi Henry Ho, Terry P. Yamaguchi, Sudhansu K. Dey
Publikováno v:
Cell Reports, Vol 8, Iss 2, Pp 382-392 (2014)
Embryo homing and implantation occur within a crypt (implantation chamber) at the antimesometrial (AM) pole along the uterus. The mechanism by which this is achieved is not known. Here, we show that villi-like epithelial projections from the main ute
Externí odkaz:
https://doaj.org/article/14bfc18ed32c4ffd9246a11e469215d3
Autor:
Risako Nakano, Aisha Yesbolatova, Yumiko Saga, Kosuke Fukui, Yuichiro Saito, Ken-ichiro Hayashi, Hirofumi Nakaoka, Kanae Gamo, Rieko Ajima, Naomi Kitamoto, Yusuke Tominari, Hatsune Makino-Itou, Masato T. Kanemaki, Haruki Takeuchi
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications
Protein knockdown using the auxin-inducible degron (AID) technology is useful to study protein function in living cells because it induces rapid depletion, which makes it possible to observe an immediate phenotype. However, the current AID system has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09efdb250e08d6e722861b8a11682068
http://link.springer.com/article/10.1038/s41467-020-19532-z
http://link.springer.com/article/10.1038/s41467-020-19532-z
Autor:
Masafumi Muraoka, Rieko Ajima, Hajime Okada, Hiroshi Mori, Yumiko Saga, Atsushi Toyoda, Jessica Kim
The evolutionarily conserved RNA helicase DDX6 is a central player of post-transcriptional regulation, but its role during embryogenesis remains elusive. We here demonstrated that DDX6 enables proper cell lineage specification from pluripotent cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b6a56094c596eb4c8dc14341eeeb8db
https://doi.org/10.1101/2021.11.29.470397
https://doi.org/10.1101/2021.11.29.470397
