Cross-disease Meta-analysis of Genome-wide Association Studies for Systemic Sclerosis and Rheumatoid Arthritis Reveals IRF4 as a New Common Susceptibility Locus

Autor: López-Isac, Elena, Martín, Jose-Ezequiel, Assassi, Shervin, Simeón, Carmen P, Carreira, Patricia, Ortego-Centeno, Norberto, Freire, Mayka, Beltrán, Emma, Narváez, Javier, Alegre-Sancho, Juan J, Fernández-Gutiérrez, Benjamín, Balsa, Alejandro, Ortiz, Ana M, González-Gay, Miguel A, Beretta, Lorenzo, Santaniello, Alessandro, Bellocchi, Chiara, Lunardi, Claudio, Moroncini, Gianluca, Gabrielli, Armando, Witte, Torsten, Hunzelmann, Nicolas, Distler, Jörg HW, Riekemasten, Gabriella, van der Helm-van Mil, Annete H, de Vries-Bouwstra, Jeska, Magro-Checa, Cesar, Voskuyl, Alexandre E, Vonk, Madelon C, Molberg, Øyvind, Merriman, Tony, Hesselstrand, Roger, Nordin, Annika, Padyukov, Leonid, Herrick, Ariane, Eyre, Steve, Koeleman, Bobby PC, Denton, Christopher P, Fonseca, Carmen, Radstake, Timothy RDJ, Worthington, Jane, Mayes, Maureen D, Martín, Javier

Systemic sclerosis (SSc) and rheumatoid arthritis (RA) are autoimmune diseases that have similar clinical and immunologic characteristics. To date, several shared SSc-RA genetic loci have been identified independently. The aim of the current study wa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::df8f94cb1a1ec07dffdf86f9ff2a254b
https://europepmc.org/articles/PMC5530728/

Brief Report: IRF4 Newly Identified as a Common Susceptibility Locus for Systemic Sclerosis and Rheumatoid Arthritis in a Cross-Disease Meta-Analysis of Genome-Wide Association Studies.

Autor: López-Isac E; Institute of Parasitology and Biomedicine López-Neyra CSIC, Granada, Spain., Martín JE; Institute of Parasitology and Biomedicine López-Neyra CSIC, Granada, Spain., Assassi S; University of Texas Health Science Center, Houston., Simeón CP; Valle de Hebrón Hospital, Barcelona, Spain., Carreira P; 12 de Octubre University Hospital, Madrid, Spain., Ortego-Centeno N; Clinic University Hospital, Granada, Spain., Freire M; Complexo Hospitalario Universitario de Vigo, Vigo, Spain., Beltrán E; Hospital General Universitario de Valencia, Valencia, Spain., Narváez J; Hospital Universitari de Bellvitge, Barcelona, Spain., Alegre-Sancho JJ; Hospital Universitari Doctor Peset, Valencia, Spain., Fernández-Gutiérrez B; Hospital Clínico San Carlos, Madrid, Spain., Balsa A; Hospital Universitario La Paz, Instituto de Investigación Sanitaria La Paz, Madrid, Spain., Ortiz AM; Hospital Universitario La Princesa, Instituto de Investigación Sanitaria La Princesa, Madrid, Spain., González-Gay MA; University of Cantabria, Santander, Spain., Beretta L; Referral Center for Systemic Autoimmune Diseases, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, Milan, Italy., Santaniello A; Referral Center for Systemic Autoimmune Diseases, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, Milan, Italy., Bellocchi C; Referral Center for Systemic Autoimmune Diseases, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, Milan, Italy., Lunardi C; Università degli Studi di Verona, Verona, Italy., Moroncini G; Università Politecnica delle Marche and Ospedali Riuniti, Ancona, Italy., Gabrielli A; Università Politecnica delle Marche and Ospedali Riuniti, Ancona, Italy., Witte T; Hannover Medical School, Hannover, Germany., Hunzelmann N; University of Cologne, Cologne, Germany., Distler JH; University of Erlangen-Nuremberg, Erlangen, Germany., Riekemasten G; University of Lübeck, Lübeck, Germany., van der Helm-van Mil AH; Leiden University Medical Center, Leiden, The Netherlands., de Vries-Bouwstra J; Leiden University Medical Center, Leiden, The Netherlands., Magro-Checa C; Leiden University Medical Center, Leiden, The Netherlands., Voskuyl AE; VU University Medical Center, Amsterdam, The Netherlands., Vonk MC; Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands., Molberg Ø; Oslo University Hospital Rikshospitalet and Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Merriman T; University of Otago, Otago, New Zealand., Hesselstrand R; Lund University, Lund, Sweden., Nordin A; Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden., Padyukov L; Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden., Herrick A; University of Manchester, Manchester Academic Health Science Centre, Manchester, UK., Eyre S; University of Manchester, Manchester Academic Health Science Centre, Manchester, UK., Koeleman BP; University Medical Center Utrecht, Utrecht, The Netherlands., Denton CP; Centre for Rheumatology, Royal Free and University College Medical School, London, UK., Fonseca C; Centre for Rheumatology, Royal Free and University College Medical School, London, UK., Radstake TR; University Medical Center Utrecht, Utrecht, The Netherlands. Members of the Spanish Scleroderma Group are shown in Appendix A., Worthington J; University of Manchester, Manchester Academic Health Science Centre, Manchester, UK., Mayes MD; University of Texas Health Science Center, Houston., Martín J; Institute of Parasitology and Biomedicine López-Neyra CSIC, Granada, Spain.

Publikováno v: Arthritis & rheumatology (Hoboken, N.J.) [Arthritis Rheumatol] 2016 Sep; Vol. 68 (9), pp. 2338-44.