Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Rieke, Frank"'
Autor:
Jürgen Wolf, Reinhard Büttner, Mathieu Clement-Ziza, Lukas C. Heukamp, Britta Kaminsky, Thomas Geist, Ulrich Gerigk, Yon-Dschun Ko, Monika Serke, Carina Heydt, Jana Fassunke, Anna Eisert, Rieke Fischer, Sebastian Michels, Katharina König, Frank Ueckeroth, Michael Rauer, Anna Kron, Michaela A. Ihle, Sabine Merkelbach-Bruse, Matthias Scheffler, Rieke Frank
Purpose: KEAP1 and NFE2L2 mutations are associated with impaired prognosis in a variety of cancers and with squamous cell carcinoma formation in non–small cell lung cancer (NSCLC). However, little is known about frequency, histology dependence, mol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::438570b1ec0685eb9b4c9f90d1ab3452
https://doi.org/10.1158/1078-0432.c.6527654.v1
https://doi.org/10.1158/1078-0432.c.6527654.v1
Autor:
Jürgen Wolf, Reinhard Büttner, Mathieu Clement-Ziza, Lukas C. Heukamp, Britta Kaminsky, Thomas Geist, Ulrich Gerigk, Yon-Dschun Ko, Monika Serke, Carina Heydt, Jana Fassunke, Anna Eisert, Rieke Fischer, Sebastian Michels, Katharina König, Frank Ueckeroth, Michael Rauer, Anna Kron, Michaela A. Ihle, Sabine Merkelbach-Bruse, Matthias Scheffler, Rieke Frank
Supplemental Table 1-7 Supplemental Table 1: Diagnostic panels used for Next-generation sequencing (NGS) Supplemental Table 2: KEAP1 mutations Supplemental Table 3: NFE2L2 mutations Supplemental Table 4: Co-aberrations of KEAP1 Supplemental Table 5:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26f036f5e01c6e1155e337dc9abeb9da
https://doi.org/10.1158/1078-0432.22470680
https://doi.org/10.1158/1078-0432.22470680
Autor:
Jürgen Wolf, Reinhard Büttner, Mathieu Clement-Ziza, Lukas C. Heukamp, Britta Kaminsky, Thomas Geist, Ulrich Gerigk, Yon-Dschun Ko, Monika Serke, Carina Heydt, Jana Fassunke, Anna Eisert, Rieke Fischer, Sebastian Michels, Katharina König, Frank Ueckeroth, Michael Rauer, Anna Kron, Michaela A. Ihle, Sabine Merkelbach-Bruse, Matthias Scheffler, Rieke Frank
Main characteristics of the control group.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90f2126ee0c9e620a395f2041814bcda
https://doi.org/10.1158/1078-0432.22470677.v1
https://doi.org/10.1158/1078-0432.22470677.v1
Autor:
Britta Kaminsky, Reinhard Büttner, Frank Ueckeroth, Anna Eisert, Jana Fassunke, Ulrich Gerigk, Carina Heydt, Yon-Dschun Ko, Mathieu Clément-Ziza, Lukas C. Heukamp, Thomas Geist, Jürgen Wolf, Matthias Scheffler, Katharina König, Anna Kron, Sabine Merkelbach-Bruse, Sebastian Michels, Monika Serke, Michaela Angelika Ihle, Rieke Frank, Michael Rauer, Rieke Fischer
Publikováno v:
Clinical Cancer Research. 24:3087-3096
Purpose: KEAP1 and NFE2L2 mutations are associated with impaired prognosis in a variety of cancers and with squamous cell carcinoma formation in non–small cell lung cancer (NSCLC). However, little is known about frequency, histology dependence, mol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0be8a3e9db755535fe7f94c4f93fa9e6
https://doi.org/10.1158/1078-0432.ccr-17-3416
https://doi.org/10.1158/1078-0432.ccr-17-3416
Autor:
Carsten Schaepers, Roman K. Thomas, Martin L. Sos, Jürgen Wolf, Imke Sauerland, Lars Hagmeyer, Reinhard Büttner, Karl-Otto Kambartel, Rebecca Hein, Lucia Nogova, Joachim Lorenz, Diana S.Y. Abdulla, Leonie Gogl, Martin Peifer, Nima Abedpour, Christian Grohé, Martin Hellmich, Johannes Brägelmann, Sophia Koleczko, Sabine Merkelbach-Bruse, Sebastian Michels, Merle Schüller, Ulrich Gerigk, Helen Pasternack, Matthias Scheffler, Rieke Fischer, Michaela Angelika Ihle, Monika Serke, Winfried Randerath, Jana Fassunke, Alessandra Holzem, Britta Kaminsky, Andreas H. Scheel, Anna Kron, Yon-Dschun Ko, Frank Ueckeroth, Wolfgang Schulte, Rieke Frank, Richard F. Riedel, Janna Siemanowski, Carina Heydt, Anna Eisert
Publikováno v:
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 14(4)
Introduction Although KRAS mutations in NSCLC have been considered mutually exclusive driver mutations for a long time, there is now growing evidence that KRAS-mutated NSCLC represents a genetically heterogeneous subgroup. We sought to determine gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::126be135328e3f2bcf25497758c58a3b
https://pubmed.ncbi.nlm.nih.gov/30605727
https://pubmed.ncbi.nlm.nih.gov/30605727
Autor:
Rieke, Frank, Matthias, Scheffler, Sabine, Merkelbach-Bruse, Michaela A, Ihle, Anna, Kron, Michael, Rauer, Frank, Ueckeroth, Katharina, König, Sebastian, Michels, Rieke, Fischer, Anna, Eisert, Jana, Fassunke, Carina, Heydt, Monika, Serke, Yon-Dschun, Ko, Ulrich, Gerigk, Thomas, Geist, Britta, Kaminsky, Lukas C, Heukamp, Mathieu, Clement-Ziza, Reinhard, Büttner, Jürgen, Wolf
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 24(13)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ada2c98e9b91a56fbffe524fcbc7f379
https://pubmed.ncbi.nlm.nih.gov/29615460
https://pubmed.ncbi.nlm.nih.gov/29615460
Autor:
Martin L. Sos, Juergen Wolf, Matthias Scheffler, Andreas H. Scheel, Sophia Koleczko, Carsten Schaepers, Frank Ueckeroth, Sabine Merkelbach-Bruse, Sebastian Michels, Leonie Gogl, Martin Hellmich, Rieke Fischer, Rieke Frank, Johannes Braegelmann, Anna Kostenko, Rebecca Hein, Michaela Angelika Ihle, Anna Eisert, Reinhard Buettner, Florian Kron
Publikováno v:
Journal of Clinical Oncology. 34:9018-9018
9018Background: KRAS mutations in non-small cell lung cancer (NSCLC) still remain therapeutically untargetable. Assuming that these mutations are not mutually exclusive with other driver aberration...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::247ca5cd4c8ac9c50ef23a1ba36c1722
https://doi.org/10.1200/jco.2016.34.15_suppl.9018
https://doi.org/10.1200/jco.2016.34.15_suppl.9018
Autor:
Rieke Fischer, Rieke Frank, Ulrich Gerigk, Monika Serke, Lukas C. Heukamp, Matthias Scheffler, Reinhard Büttner, Katharina Koenig, Anne M. Schultheis, Anna Eisert, Thomas Geist, Sabine Merkelbach-Bruse, Sebastian Michels, Juergen Wolf, Yon-Dschun Ko
Publikováno v:
Journal of Clinical Oncology. 33:8088-8088
8088 Background: Amplification of cMET has been described as mechanism underlying resistance to EGFR-targeted therapy in EGFR-mutated NSCLC. Nevertheless, few is known about cMET amplification besi...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3793812171fa4e8463e82c70076486f4
https://doi.org/10.1200/jco.2015.33.15_suppl.8088
https://doi.org/10.1200/jco.2015.33.15_suppl.8088
Autor:
Juergen Wolf, Lukas C. Heukamp, Sabine Merkelbach-Bruse, Sebastian Michels, Yon-Dschun Ko, Monika Serke, Anna Eisert, Matthias Scheffler, Reinhard Büttner, Katharina Koenig, Thomas Geist, Rieke Frank, Rieke Fischer, Ulrich Gerigk
Publikováno v:
Journal of Clinical Oncology. 33:8097-8097
8097 Background: Mutations in genes of the KEAP1-NFE2L2 pathway of patients with NSCLC are associated with an increased tumor growth, resistence towards cytostatic drugs and reduced survival rates....
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8605d0a3cc49c40872a3368f16bacd7
https://doi.org/10.1200/jco.2015.33.15_suppl.8097
https://doi.org/10.1200/jco.2015.33.15_suppl.8097