Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Rie Teraoka"'
Autor:
Hiroyuki Iso, Kiyouhisa Ohnishi, Hiroshi Takuma, Hiroshi Mori, Takami Tomiyama, Hiroyuki Shimada, Rie Teraoka, Mary P. Lambert, Kazuchika Nishitsuji, Shogo Matsuyama, Takenari Yamashita, Kenichi Ishibashi, Naomi Sakama, Tomohiro Umeda, Kazuhiro Ito, William L. Klein
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 30(14)
Although amyloid beta (Abeta) oligomers are presumed to cause synaptic and cognitive dysfunction in Alzheimer's disease (AD), their contribution to other pathological features of AD remains unclear. To address the latter, we generated APP transgenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::692c8329c1f830ec06125f76c7dd6a2c
https://pubmed.ncbi.nlm.nih.gov/20371804
https://pubmed.ncbi.nlm.nih.gov/20371804
Autor:
Kenichi Ishibashi, Rie Teraoka, Mary P. Lambert, Kazuchika Nishitsuji, Takami Tomiyama, Hiroshi Mori, Kazuhiro Ito, William L. Klein
The E693Delta mutation within the amyloid precursor protein (APP) has been suggested to cause dementia via the enhanced formation of synaptotoxic amyloid beta (Abeta) oligomers. However, this mutation markedly decreases Abeta secretion, implying the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6ff3772e34de52ce683d525aa55c19b
https://europepmc.org/articles/PMC2665755/
https://europepmc.org/articles/PMC2665755/
Autor:
Ryozo Kuwano, Hiroyuki Shimada, Yasuyoshi Watanabe, Masaki Imagawa, Rie Teraoka, Hiroshi Takuma, Hiroshi Mori, Tetsu Nagata, Akiko Fukushima, Suzuka Ataka, Eito Yoshioka, Yasuhiro Wada, Hyoue Kanemitsu, Tomoyuki Nishizaki, Takami Tomiyama
Publikováno v:
Alzheimer's & Dementia. 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a532c405a96d2ccda7e39e35fe9f12a
https://doi.org/10.1016/j.jalz.2008.05.552
https://doi.org/10.1016/j.jalz.2008.05.552
Publikováno v:
Neuroreport. 19(6)
We recently identified a novel amyloid precursor protein mutation (E693Delta) in familial Alzheimer's-type dementia. This mutation produces amyloid-beta (Abeta) variant lacking glutamate-22 (E22Delta), which showed enhanced oligomerization but no fib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e80fd772d1b598d2f5be4810ef3ca543
https://pubmed.ncbi.nlm.nih.gov/18382273
https://pubmed.ncbi.nlm.nih.gov/18382273
Publikováno v:
Neuroreport. 18(10)
Soluble amyloid beta peptide (Abeta) is believed to cause synaptic dysfunction in the early stages of Alzheimer's disease. Here, we examined in-vivo synaptic functions in the hippocampus in two lines of transgenic mice expressing different amounts of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1e54139300d6937648f1bc3544c992f
https://pubmed.ncbi.nlm.nih.gov/17632268
https://pubmed.ncbi.nlm.nih.gov/17632268