Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Rie Takashima"'
Publikováno v:
Genes and Environment, Vol 46, Iss 1, Pp 1-7 (2024)
Abstract Background Di(2-ethylhexyl) phthalate (DEHP) is a plasticizer commonly used in a wide variety of products, including medical devices. It is rapidly metabolized in the liver into various metabolites upon absorption through oral ingestion, der
Externí odkaz:
https://doaj.org/article/ab00754d305443eca6bee266ad4bf942
Autor:
Hidemasa Katsumi, Sho Kitada, Shintaro Yasuoka, Rie Takashima, Tomoki Imanishi, Rina Tanaka, Satoru Matsuura, Hiroyuki Kimura, Hidekazu Kawashima, Masaki Morishita, Akira Yamamoto
Publikováno v:
Pharmaceutics, Vol 14, Iss 9, p 1946 (2022)
In the present study, L-serine (Ser)-modified poly-L-lysine (PLL) was synthesized to develop a biodegradable, kidney-targeted drug carrier for efficient radionuclide therapy in renal cell carcinoma (RCC). Ser-PLL was labeled with 111In/90Y via diethy
Externí odkaz:
https://doaj.org/article/91dbc3c07233444ba57cd9aac5c41774
Autor:
Halima Sultana, Ayaka Kato, Ai Ohashi, Rie Takashima, Tomoko Katsurai, Shoko Sato, Masafumi Monma, Yusuke Ohsaki, Tomoko Goto, Michio Komai, Hitoshi Shirakawa
Publikováno v:
Nutrients, Vol 13, Iss 5, p 1709 (2021)
The pregnane X receptor (PXR) is the key regulator of our defense mechanism against foreign substances such as drugs, dietary nutrients, or environmental pollutants. Because of increased health consciousness, the use of dietary supplements has gradua
Externí odkaz:
https://doaj.org/article/b99e125f747f4ba2ac0685d85765ea71
Autor:
Satoru Matsuura, Hidemasa Katsumi, Hiroe Suzuki, Natsuko Hirai, Rie Takashima, Masaki Morishita, Toshiyasu Sakane, Akira Yamamoto
Publikováno v:
Pharmaceutics, Vol 10, Iss 4, p 251 (2018)
l-cysteine (Cys)- and l-serine (Ser)-modified, third-generation polyamidoamine (PAMAM) dendrimer with multiple reduced thiols (Ser-PAMAM-Cys) was synthesized as a kidney-targeting reactive oxygen species (ROS) scavenger to help prevent renal ischemia
Externí odkaz:
https://doaj.org/article/20cecb29c0eb46bd81d3c66890e68917
Autor:
Halima Sultana, Kimika Watanabe, Md Masud Rana, Rie Takashima, Ai Ohashi, Michio Komai, Hitoshi Shirakawa
Publikováno v:
Nutrients, Vol 10, Iss 8, p 982 (2018)
Pregnane X receptor (PXR) is a nuclear receptor activated by various compounds, including prescribed drugs and dietary ingredients. Ligand-specific activation of PXR alters drug metabolism and affects many other physiological conditions. Species-spec
Externí odkaz:
https://doaj.org/article/fa23d0a0af7a483b809978fb9c55856d
Autor:
Rie Takashima, Masaki Morishita, Hiroyuki Kimura, Hiroe Suzuki, Hidemasa Katsumi, Natsuko Hirai, Satoru Matsuura, Akira Yamamoto
Publikováno v:
Free Radical Research. 54:841-847
Nitric oxide (NO) deficiency is known to play a role in renal ischaemia/reperfusion injury; therefore, kidney-targeting NO donor is expected to prevent renal ischaemia/reperfusion injury. We therefore developed an S-nitrosylated L-serine-modified pol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6cb2de94733c6bb04817fefb0140054
https://doi.org/10.1080/10715762.2019.1697437
https://doi.org/10.1080/10715762.2019.1697437
Autor:
Ayaka Kato, Shoko Sato, Yusuke Ohsaki, Hitoshi Shirakawa, Michio Komai, Halima Sultana, Tomoko Goto, Ai Ohashi, Rie Takashima, Tomoko Katsurai, Masafumi Monma
Publikováno v:
Nutrients
Nutrients, Vol 13, Iss 1709, p 1709 (2021)
Volume 13
Issue 5
Nutrients, Vol 13, Iss 1709, p 1709 (2021)
Volume 13
Issue 5
The pregnane X receptor (PXR) is the key regulator of our defense mechanism against foreign substances such as drugs, dietary nutrients, or environmental pollutants. Because of increased health consciousness, the use of dietary supplements has gradua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7cf3bab2bd6997b6834fe6bcefcda96
https://pubmed.ncbi.nlm.nih.gov/34069974
https://pubmed.ncbi.nlm.nih.gov/34069974
Autor:
Natsuko Hirai, Hiroe Suzuki, Rie Takashima, Toshiyasu Sakane, Masaki Morishita, Hidemasa Katsumi, Satoru Matsuura, Akira Yamamoto
Publikováno v:
Pharmaceutics, Vol 10, Iss 4, p 251 (2018)
Pharmaceutics
Volume 10
Issue 4
Pharmaceutics
Volume 10
Issue 4
l-cysteine (Cys)- and l-serine (Ser)-modified, third-generation polyamidoamine (PAMAM) dendrimer with multiple reduced thiols (Ser-PAMAM-Cys) was synthesized as a kidney-targeting reactive oxygen species (ROS) scavenger to help prevent renal ischemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49638fa5166eb8d357c467d8bcc8b11e
https://www.mdpi.com/1999-4923/10/4/251
https://www.mdpi.com/1999-4923/10/4/251
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. :35-39
The liver micronucleus (MN) assay is an effective and important in vivo test for detecting genotoxic compounds, particularly those that require metabolic activation. For this assay, hepatocytes (HEPs) can be isolated by collagenase treatment but with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6f58d5cd622cd9e60b619445d017111
https://doi.org/10.1016/j.mrgentox.2016.03.004
https://doi.org/10.1016/j.mrgentox.2016.03.004
Autor:
Rie Takashima, Hitoshi Shirakawa, Masud Rana, Michio Komai, Ai Ohashi, Kimika Watanabe, Halima Sultana
Publikováno v:
Nutrients, Vol 10, Iss 8, p 982 (2018)
Nutrients
Volume 10
Issue 8
Nutrients
Volume 10
Issue 8
Pregnane X receptor (PXR) is a nuclear receptor activated by various compounds, including prescribed drugs and dietary ingredients. Ligand-specific activation of PXR alters drug metabolism and affects many other physiological conditions. Species-spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2710277195b6bd6a0d98306cd52b5229
http://www.mdpi.com/2072-6643/10/8/982
http://www.mdpi.com/2072-6643/10/8/982