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Autor:
Masayuki Haruta, Kazunori Nishida, Masashi Kurosumi, Yasuhito Kobayashi, Yuiko Fujiwara, Yasuhiko Kaneko, Rie Hosaka, Fumio Kasai, Kiwamu Akagi, Waka Sugawara, Yasuhito Arai
Publikováno v:
Genes, Chromosomes and Cancer. 50:535-545
Germline TP53 mutations are found in Li-Fraumeni syndrome (LFS) patients, predisposed to soft tissue sarcoma and other malignancies. The mutations and succeeding genetic events are thought to cause LFS-associated cancer, whose genetic alterations hav