Výsledky vyhledávání - "Ricquita D Pollard"

What does procollagen C-endopeptidase enhancer protein 2 have to do with HDL-cholesteryl ester uptake? Or how I learned to stop worrying and love reverse cholesterol transport?

Autor: Mary G. Sorci-Thomas, Ricquita D. Pollard, Michael J. Thomas

Publikováno v: Current Opinion in Lipidology

Purpose of review The purpose of this study is to provide an update on the role HDL apolipoprotein A-I plays in reducing the risk of cardiovascular disease (CVD) and how it relates to reverse cholesterol transport (RCT). Recent findings Despite numer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fecfe3e18acc34506a9ece660395995c
https://doi.org/10.1097/mol.0000000000000211

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The Conformation of Lipid-Free Human Apolipoprotein A-I in Solution

Autor: Brian Fulp, Michael J. Thomas, Michael P. Samuel, Mary G. Sorci-Thomas, Ricquita D. Pollard

Publikováno v: Biochemistry. 52:9470-9481

Apolipoprotein AI (apoA-I) is the principal acceptor of lipids from ATP-binding cassette transporter A1, a process that yields nascent high density lipoproteins. Analysis of lipidated apoA-I conformation yields a belt or twisted belt in which two str

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4b81ca473cd201eb95bfc4f53083835
https://doi.org/10.1021/bi401080k

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Procollagen C-endopeptidase Enhancer Protein 2 (PCPE2) Reduces Atherosclerosis in Mice by Enhancing Scavenger Receptor Class B1 (SR-BI)-mediated High-density Lipoprotein (HDL)-Cholesteryl Ester Uptake*

Autor: Ricquita D. Pollard, Mary G. Sorci-Thomas, Xiang-An Li, Mark Gerelus, Xuewei Zhu, Nebil Nuradin, Daisy Sahoo, Michael J. Thomas, Christopher N. Blesso, Brian Fulp, Manal Zabalawi, Omar L. Francone, Erica W. Lyons

Studies in human populations have shown a significant correlation between procollagen C-endopeptidase enhancer protein 2 (PCPE2) single nucleotide polymorphisms and plasma HDL cholesterol concentrations. PCPE2, a 52-kDa glycoprotein located in the ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe20ea84615f93b657f171120988ef9f
https://europepmc.org/articles/PMC4505464/

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Abstract 320: Procollagen C-Endopeptidase Enhancer Protein 2 Enhances SR-BI Mediated HDL Cholesterol Uptake and Reduces Atherosclerosis in Mice

Autor: Ricquita D. Pollard, Brian Fulp, Omar L. Francone, Manal Zabalawi, Nebil Nuradin, Erica L. Lyons, Michael J. Thomas, Mark Gerelus, Daisy Sahoo, Christopher N. Blesso, Xiang-An Li, Xuewei Zhu

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 35

Epidemiological studies have shown an inverse correlation between plasma high density lipoprotein (HDL) concentrations and cardiovascular disease risk. At variance with these observations, clinical trials that significantly raised plasma HDL-C levels

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bf0c27bb90260f8035218b31d414f5b7
https://doi.org/10.1161/atvb.35.suppl_1.320

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Abstract 116: Mechanism of ApoA-I Attenuation of Inflammation Associated with Atherosclerosis

Autor: Nebil Nuradin, Ricquita D Pollard, Manal Zabalawi, Brian Pulp, Mary G Sorci-Thomas, Michael J Thomas

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 35

Cytokines/chemokines and their receptors have been an important consideration when investigating the role of inflammation in atherosclerosis. In humans and animal models, monocyte recruitment and accumulation within the artery wall occurs in response

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5ed0770e095f8b155a1a9ef0e94edf48
https://doi.org/10.1161/atvb.35.suppl_1.116

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Abstract 224: Formation of Cholesterol-Enriched Nascent HDL Requires Helices 5 and 7

Autor: Ricquita D Pollard, Brian Fulp, Michael P Samuel, Mary G Sorci-Thomas, Michael J Thomas

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 34

Heart disease claims nearly 400,000 individuals in the US per year. Large population studies have repeatedly demonstrated an inverse relationship between HDL concentration and risk. Despite the strong correlation, pharmacological trials that raise pl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::06dae469bab1abd5c0f79e984f866bf6
https://doi.org/10.1161/atvb.34.suppl_1.224

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Abstract 430: PCPE2 a Novel Determinant in HDL Biogenesis and Metabolism

Autor: Ricquita D Pollard, Erica Weiser, Christopher Blesso, Manal Zabalawi, Brian Fulp, Michael J Thomas, Mary G Sorci-Thomas

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 33

Recent attempts to reduce cardiovascular events by pharmacologically raising plasma HDL concentration have not proven efficacious. This has lead to investigations on how to increase functional versus dysfunctional plasma HDL. Our work shows that a fu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9986d62c2f5cc5910461c044c02696b0
https://doi.org/10.1161/atvb.33.suppl_1.a430

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