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pro vyhledávání: '"Rico K.H. Lo"'
Autor:
Andrew M.F. Liu, Yung Hou Wong, Rico K.H. Lo, Wendy W.S. Yeung, Maurice K.C. Ho, Maggie M. K. Lee, Yingchun Wang, Yan Su, Richard D. Ye
Publikováno v:
Cellular Signalling. 22:1448-1458
Many G protein-coupled receptors (GPCRs) are known to modulate cell growth and differentiation by stimulating the extracellular signal-regulated protein kinases (ERKs). In growth factor signaling, ERKs are typically stimulated through an elaborate ne
Autor:
Frances W.Y. Yu, Anthony S.L. Chan, Yung Hou Wong, Rico K.H. Lo, Jessie W. F. Yuen, Lydia See Wing Poon
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 42:1052-1059
The hematopoietic-specific Gq subfamily members, Gα16 and Gα14 proteins have recently been shown to be capable of stimulating the signal transducer and activator of transcription 3 (STAT3) as well as STAT1. In the present study we examined whether
Publikováno v:
Cellular Signalling. 20:2095-2106
Human prostacyclin receptor (hIP) stimulates STAT3 via pertussis toxin-insensitive G proteins in human erythroleukemia (HEL) cells. Since hIP can utilize G(s) and G(q) proteins for signal transduction and that both G proteins can induce STAT3 phospho
Autor:
Rico K.H. Lo, Yung Hou Wong
Publikováno v:
Molecular Pharmacology. 65:1427-1439
The hematopoietic-specific Galpha14 links a variety of G protein-coupled receptors to phospholipase Cbeta (PLCbeta) stimulation. Recent studies reveal that several Galpha subunits are capable of activating signal transducer and activator of transcrip
Publikováno v:
Methods in Molecular Biology ISBN: 9781603275446
Reporter gene assays are versatile and sensitive methods of assaying numerous targets in high-throughput drug-screening programs. A variety of reporter genes allow users a choice of signal that can be tailored to the required sensitivity, the availab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c4c71212226d7dd6b108ac37f08006d
https://doi.org/10.1007/978-1-60327-545-3_8
https://doi.org/10.1007/978-1-60327-545-3_8
Autor:
Yung Hou Wong, Rico K.H. Lo
Publikováno v:
Cellular signalling. 18(12)
Hematopoietic restrictive Galpha(16) has long been known to stimulate phospholipase Cbeta (PLCbeta) and induce mitogen-activated protein kinase (MAPK) phosphorylation. Recently, we have demonstrated that Galpha(16) is capable of inducing the phosphor
Publikováno v:
Cellular signalling. 18(3)
The ability of the human prostacyclin receptor (hIP) to regulate the activities of signal transducers and activators of transcription (STATs) has not yet been documented. In the present study, we have delineated the mechanism by which hIP induces STA
Publikováno v:
The Journal of biological chemistry. 278(52)
The hematopoietic-specific Galpha16 protein has recently been shown to mediate receptor-induced activation of the signal transducer and activator of transcription 3 (STAT3). In the present study, we have delineated the mechanism by which Galpha16 sti
Publikováno v:
Biochemical and biophysical research communications. 303(3)
A number of G protein-coupled receptors (GPCRs) have been shown to stimulate signal transducers and activators of transcription (STAT) activities while STAT3 activation by G alpha(o) can lead to neoplastic transformation in fibroblasts. In the presen
Autor:
Eric J. Stanbridge, Anthony S.L. Chan, Tatyana A. Voyno-Yasenetskaya, Rico K.H. Lo, Frank P.L. Lai, Yung Hou Wong
Publikováno v:
Cellular signalling. 14(3)
Melatonin is a pineal hormone involved in neuroendocrine processes in mammals. It has been shown that melatonin inhibits the enzymatic activities of adenylyl cyclases and the transcriptional activities of CREB. In this report, we demonstrate that 2-i