Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Rico Chandra Ardy"'
Autor:
Julia E Sero, Heba Zuhair Sailem, Rico Chandra Ardy, Hannah Almuttaqi, Tongli Zhang, Chris Bakal
Publikováno v:
Molecular Systems Biology, Vol 11, Iss 3, Pp n/a-n/a (2015)
Abstract Although a great deal is known about the signaling events that promote nuclear translocation of NF‐κB, how cellular biophysics and the microenvironment might regulate the dynamics of this pathway is poorly understood. In this study, we us
Externí odkaz:
https://doaj.org/article/9e159c8842f1468e860ed1768eef723e
Publikováno v:
Immunological Reviews
Summary Rare, monogenetic diseases present unique models to dissect gene functions and biological pathways, concomitantly enhancing our understanding of the etiology of complex (and often more common) traits. Although inflammatory bowel disease (IBD)
Autor:
Vahid Ziaee, Stephanie Stahnke, Rico Chandra Ardy, Johannes B. Huppa, Kaan Boztug, Klemens Rottner, Celine Sin, David Medgyesi, Michael Caldera, Jörg Menche, Nima Rezaei, Christina Rashkova, Michael Sixt, Christoph Bock, Matthias Haimel, Loïc Dupré, Samaneh Zoghi, M. Kiss, René Platzer, Jana Block, Peter Hammerl, Frieda Kage, Elisabeth Salzer, Sepideh Shahkarami, Christoph J. Binder, Birgit Hoeger, Theresia E. B. Stradal, Alexis J. Lomakin, Renate Kain
Publikováno v:
Science Immunology
Sci Immunol
Sci Immunol
The WAVE regulatory complex (WRC) is crucial for assembly of the peripheral branched actin network constituting one of the main drivers of eukaryotic cell migration. Here, we uncover an essential role of the hematopoietic-specific WRC component HEM1
Autor:
Enrico Girardi, van der Burg M, Javier Martinez, Rico Chandra Ardy, Cecilia Domínguez Conde, Elisabeth Salzer, Ahmet Ozen, Özlem Yüce Petronczki, Stefan Weitzer, Kaan Boztug, Ana Krolo, Winfried F. Pickl, Ijspeert H, Katharina L. Willmann, Elif Karakoc-Aydiner, Safa Baris, Ayca Kiykim, Giulio Superti-Furga, Leo Kager, Joanna I. Loizou, Elisabeth Förster-Waldl
Publikováno v:
Journal of Clinical Investigation, 129(10), 4194-4206. AMER SOC CLINICAL INVESTIGATION INC
Polymerase delta is essential for eukaryotic genome duplication and synthesizes DNA at both the leading and lagging strands. The polymerase delta complex is a heterotetramer comprising the catalytic subunit POLD1 and the accessory subunits POLD2, POL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fd94005bae7aeaafaad7ae447e5c8ef
http://hdl.handle.net/1887/121733
http://hdl.handle.net/1887/121733
Autor:
James Thaventhiran, Duncan I. Jodrell, Fiona Shackley, Chi Ma, Joshua D. Milner, Daniel Greene, Alison M. Condliffe, Ruth A. Sabroe, Meltem Gürel, Guangping Sun, Sarah Spencer, William Rae, Katarzyna D. Kania, William Egner, Jonathan Stephens, Emily Staples, Adrian J. Thrasher, Ernest Turro, Hana Lango Allen, Diarmuid Kerrin, Yuan Zhang, Ravishankar Sargur, Hye Sun Kuehn, Sevgi Köstel Bal, Salih Tuna, Melanie York, Rico Chandra Ardy, Kenneth G. C. Smith, Sergio D. Rosenzweig, Tala Shahin, Annika Pecchia-Bekkum, Marini Thian, William P.M. Worrall, Simon Tavaré, Syed Irfan Raza, Hamid Nawaz Tipu, Matthew A. Brown, Kaan Boztug
Publikováno v:
The Journal of Experimental Medicine
Spencer et al. report the first description of human IL-6R deficiency in two patients presenting with recurrent infections, atopy, elevated IgE, and abnormal acute-phase responses.
IL-6 excess is central to the pathogenesis of multiple inflammat
IL-6 excess is central to the pathogenesis of multiple inflammat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b03fdfef3871cfdc30da1f97de7498f
https://www.repository.cam.ac.uk/handle/1810/293791
https://www.repository.cam.ac.uk/handle/1810/293791
Autor:
Elisangela Santos-Valente, Jordan S. Orange, Peter Priftakis, Anna Schrempf, Elisabeth Förster-Waldl, Salomé Glauzy, Jean Nicolas Schickel, Nina K. Serwas, David Medgyesi, Alan Kennedy, Renate Kain, Eric Meffre, Emily M. Mace, Özlem Yüce Petronczki, Nima Memaran, Ana Krolo, Ivan Bilic, Bettina Bidmon-Fliegenschnee, Jakob Huemer, Pinaki P. Banerjee, Iro Pierides, Sigrun V. Stulz, Tie Z. Hou, Zhenhua Sui, Elisabeth Salzer, Laurène Pfajfer, Marie Meeths, Neil Halliday, Wojciech Garncarz, Yenan T. Bryceson, Rico Chandra Ardy, Jens Thiel, Amnon Altman, Joanna I. Loizou, Malini Mukherjee, Birgit Hoeger, Artem Kalinichenko, Bianca Tesi, Kaan Boztug, Wolf Dietrich Huber, Winfried F. Pickl, David M. Sansom
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-2 (2019)
Nature Communications
Nature Communications
Immune responses need to be controlled tightly to prevent autoimmune diseases, yet underlying molecular mechanisms remain partially understood. Here, we identify biallelic mutations in three patients from two unrelated families in differentially expr
Autor:
Kaan Boztug, Ömür Ardeniz, Birgit Hoeger, Nina K. Mair, Rico Chandra Ardy, Johannes B. Huppa, Mirjam van der Burg, Hanna IJspeert, Ferah Genel, Christoph Madritsch, Sevgi Köstel Bal, Bengü Gerçeker, Laurène Pfajfer, Stuart G. Tangye, Ingrid Simonitsch-Klupp, Raul Jimenez-Heredia, Javier Rey-Barroso, Nesrin Gulez, Loïc Dupré, Artem Kalinichenko
Publikováno v:
Journal of Allergy and Clinical Immunology, 142(5), 1589-+. Mosby Inc.
Background: The actin-interacting protein WD repeat–containing protein 1 (WDR1) promotes cofilin-dependent actin filament turnover. Biallelic WDR1 mutations have been identified recently in an immunodeficiency/autoinflammatory syndrome with aberran
Autor:
Kaan Boztug, H Rohrbach, Rico Chandra Ardy, J Dmytrus, J SeidererNack, Raul Jimenez-Heredia, I Iesalnieks
Publikováno v:
Zeitschrift für Gastroenterologie. 56:e221-e222
Autor:
Megan K. Bartlett, Shanwen Sun, Ya Zhang, Lawren Sack, Rico Chandra Ardy, Kun-Fang Cao, Nissa Kreidler
Publikováno v:
Ecology Letters. 17:1580-1590
Many species face increasing drought under climate change. Plasticity has been predicted to strongly influence species' drought responses, but broad patterns in plasticity have not been examined for key drought tolerance traits, including turgor loss
Publikováno v:
BioEssays. 36:1195-1203
Through statistical analysis of datasets describing single cell shape following systematic gene depletion, we have found that the morphological landscapes explored by cells are composed of a small number of attractor states. We propose that the topol