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pro vyhledávání: '"Ricky Lieu"'
Autor:
Ricky Lieu, Stephen Antonysamy, Zhanna Druzina, Carolyn Ho, N Rebecca Kang, Anna Pustilnik, Jing Wang, Shane Atwell
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0232311 (2020)
Antibody therapeutics are one of the most important classes of drugs. Antibody structures have become an integral part of predicting the behavior of potential therapeutics, either directly or as the basis of modeling. Structures of Fab:antigen comple
Externí odkaz:
https://doaj.org/article/ebdd6cf4580740df8d79dbe42804a89c
Autor:
Thea Norman, Tsotne Javahishvili, Stuart Bussell, David C. Litzinger, Stephanie Chu, Bruce E. Kimmel, Ricky Lieu, Sami Kaphle, Bee-Cheng Sim, Peter G. Schultz, Thomas L. Daniel, Mike Ong, Anna-Maria A. Hays Putnam, Zhenwei Maio, Ying Buechler, Richard D. DiMarchi, Ho Cho, Andrew R. Hoffman, Guillermo Viramontes, Paola Castiglioni, Douglas W. Axelrod, Becky Gc, Vadim Kraynov, Nick Knudsen
Publikováno v:
Proceedings of the National Academy of Sciences. 108:9060-9065
The ribosomal incorporation of nonnative amino acids into polypeptides in living cells provides the opportunity to endow therapeutic proteins with unique pharmacological properties. We report here the first clinical study of a biosynthetic protein pr
Autor:
Arlene Sereno, Brian Kuhlman, Xiufeng Wu, F. Huang, Micheal A. Batt, Steven M. Lewis, Andrew L. Glasebrook, Ricky Lieu, Cody Fine, Carina Torres, S.J. Demarest, J.R. Fitchett, Caroline Weldon
A myriad of innovative bispecific antibody (BsAb) platforms have been reported. Most require significant protein engineering to be viable from a development and manufacturing perspective. Single-chain variable fragments (scFvs) and diabodies that con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0588a462f07d25db3bbc907d734eae12