Výsledky vyhledávání - "Ricky L. Cain"

Novel and Selective Small Molecule Stimulators of Osteoprotegerin Expression Inhibit Bone Resorption

Autor: Tina Fuson, Srinivasan Chandrasekhar, Rebecca R. Miles, Renee Emkey, David L. Halladay, Rachelle J. Sells Galvin, Yanping Xu, Ricky L. Cain, Henry Uhlman Bryant, T. John Martin, Kannan Thirunavukkarasu, Yanfei L. Ma, Qing Qiang Zeng, Jude E. Onyia, Xuhao Yang

Publikováno v: Journal of Pharmacology and Experimental Therapeutics. 309:369-379

Osteoprotegerin (OPG), a secreted member of the tumor necrosis factor receptor superfamily, is a potent inhibitor of osteoclast formation and bone resorption. Because OPG functions physiologically as a locally generated (paracrine) factor, we used hi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bb15a45871691a6e00e4f1dfab2a7aa
https://doi.org/10.1124/jpet.103.057893

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Comparison of Recombinant Human PTH(1-34) (LY333334) with a C-Terminally Substituted Analog of Human PTH-Related Protein(1-34) (RS-66271): In Vitro Activity and In Vivo Pharmacological Effects in Rats

Autor: Armen H. Tashjian, Ricky L. Cain, Janet M. Hock, Charles A. Frolik, S. Chandrasekhar, Masahiko Sato, Anita K. Harvey, Elwood C. Black

Publikováno v: Journal of Bone and Mineral Research. 14:163-172

Parathyroid hormone (PTH) and PTH-related protein (PTHrP) are believed to exert their biological actions through binding and activation of a common cell surface receptor. Recently, an analog of PTHrP (RS-66271), was described that demonstrated reduce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f65715d334a61744dc511e9f4a1700af
https://doi.org/10.1359/jbmr.1999.14.2.163

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