Výsledky vyhledávání - "Ricky A Sharma"

Akademický článek

Challenges and Opportunities With the Use of Hypofractionated Radiation Therapy in Cancer Care: Regional Perspectives From South Korea, Japan, Singapore, and Australia

Autor: Tetsuo Akimoto, MD, Hidefumi Aoyama, MD, Melvin L.K. Chua, MBBS, FRCR, PhD, FAMS, Dasantha Jayamanne, MD, Takashi Mizowaki, MD, PhD, Lucinda Morris, MBBS, Hiroshi Onishi, MD, Si Yeol Song, MD, Youssef H. Zeidan, MD, PhD, Ricky A. Sharma, MA, MB, BChir, FRCP, FRCR, PhD

Publikováno v: Advances in Radiation Oncology, Vol 8, Iss 6, Pp 101291- (2023)

Hypofractionated radiotherapy schedules provide higher per-fraction radiation doses delivered in fewer fractions than conventional schedules. This novel delivery method is supported by a large body of clinical trial evidence across various cancer sit

Externí odkaz: https://doaj.org/article/b78cce79a6e843f5863da9aea44e837b

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Akademický článek

Lung Organotypic Slices Enable Rapid Quantification of Acute Radiotherapy Induced Toxicity

Autor: Maxime Dubail, Sophie Heinrich, Lucie Portier, Jessica Bastian, Lucia Giuliano, Lilia Aggar, Nathalie Berthault, José-Arturo Londoño-Vallejo, Marta Vilalta, Gael Boivin, Ricky A. Sharma, Marie Dutreix, Charles Fouillade

Publikováno v: Cells, Vol 12, Iss 20, p 2435 (2023)

To rapidly assess healthy tissue toxicities induced by new anti-cancer therapies (i.e., radiation alone or in combination with drugs), there is a critical need for relevant and easy-to-use models. Consistent with the ethical desire to reduce the use

Externí odkaz: https://doaj.org/article/ef3dbdb660124597aecf336248a066ab

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Akademický článek

Combination of ablation and embolization for intermediate-sized liver metastases from colorectal cancer: what can we learn from treating primary liver cancer?

Autor: Matthew J. Seager, Tobias F. Jakobs, Ricky A. Sharma, Steve Bandula

Publikováno v: Diagnostic and Interventional Radiology, Vol 27, Iss 5, Pp 677-683 (2021)

Colorectal cancer liver metastases (CRLMs) are common. Treating CRLMs with thermal ablation can prolong survival, but compared to lesions smaller than 3 cm, local control rates and overall survival are relatively worse with larger, intermediate (3–

Externí odkaz: https://doaj.org/article/60a8d2c25a724e658ff19afe6a73a586

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Akademický článek

Identification of anticancer drugs to radiosensitise BRAF-wild-type and mutant colorectal cancer

Autor: Rebecca Carter, Azadeh Cheraghchi-Bashi, Adam Westhorpe, Sheng Yu, Yasmin Shanneik, Elena Seraia, Djamila Ouaret, Yasuhiro Inoue, Catherine Koch, Jenny Wilding, Daniel Ebner, Anderson J. Ryan, Francesca M. Buffa, Ricky A. Sharma

Publikováno v: Cancer Biology & Medicine, Vol 16, Iss 2, Pp 234-246 (2019)

Objective Patients with BRAF-mutant colorectal cancer (CRC) have a poor prognosis. Molecular status is not currently used to select which drug to use in combination with radiotherapy. Our aim was to identify drugs that radiosensitise CRC cells with k

Externí odkaz: https://doaj.org/article/20f6deba4d8f477f8d7767514aae6c9b

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Akademický článek

Long-term radiological and histological outcomes following selective internal radiation therapy to liver metastases from breast cancer

Autor: Paul C. Lyon, BSc, MSc, MRCS, MRes, DPhil, Helen Winter, BSc, MBBS, MSc, MRCP, FRACP, Karin Herbschleb, MRCP, Leticia Campo, Diploma, Robert Carlisle, PhD, Feng Wu, MD, PhD, Robert Goldin, MD, MEd, FRCPath, Constantin C. Coussios, PhD, Mark R. Middleton, BA, MA, PhD, FRCP, Fergus V. Gleeson, FRCR, FRCP, Philip Boardman, FRCR, Ricky A. Sharma, MB, BChir, MA, PhD, FRCP, FRCR

Publikováno v: Radiology Case Reports, Vol 13, Iss 6, Pp 1259-1266 (2018)

Liver metastasis from breast cancer is associated with poor prognosis and is a major cause of early morbidity and mortality. When liver resection is not feasible, minimally invasive directed therapies are considered to attempt to prolong survival. Se

Externí odkaz: https://doaj.org/article/20f6dd12649d40dc90fb887054b18b43

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Akademický článek

Differential clonal evolution in oesophageal cancers in response to neo-adjuvant chemotherapy

Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)

Oesophageal adenocarcinoma is often treated with chemotherapy before surgery. Here, the authors sequence cancer samples before and after chemotherapy and examine how the genome changes, focusing on changes in driver gene mutations and differential cl

Externí odkaz: https://doaj.org/article/1aea2f25e1f04ce696257305762bffaf

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