Zobrazeno 1 - 10
of 211
pro vyhledávání: '"Ricki J, Colman"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Lower urinary tract (LUT) dysfunction is prevalent in the elderly population, and clinical manifestations include urinary retention, incontinence, and recurrent urinary tract infections. Age-associated LUT dysfunction is responsible for sign
Externí odkaz:
https://doaj.org/article/6bfcc151baa941428720332781bb8839
Autor:
Alex B. Smith, Jonah P. Schill, Ruth Gordillo, Grace E. Gustafson, Timothy W. Rhoads, Maggie S. Burhans, Aimee T. Broman, Ricki J. Colman, Philipp E. Scherer, Rozalyn M. Anderson
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Metabolic syndrome increases risk of complicating co-morbidities. Current clinical indicators reflect established metabolic impairment, preventing earlier intervention strategies. Here we show that circulating sphingolipids are altered in th
Externí odkaz:
https://doaj.org/article/43f3986a7da74abcbd070096cce668a7
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2023)
Depression and anxiety are some of the most prevalent and debilitating mental health conditions in humans. They can present on their own or as co-morbidities with other disorders. Like humans, non-human primates (NHPs) can develop depression- and anx
Externí odkaz:
https://doaj.org/article/71116da2876440a89823fc84071c760b
Autor:
Priya Balasubramanian, Anne E Schaar, Grace E Gustafson, Alex B Smith, Porsha R Howell, Angela Greenman, Scott Baum, Ricki J Colman, Dudley W Lamming, Gary M Diffee, Rozalyn M Anderson
Publikováno v:
eLife, Vol 11 (2022)
The loss of skeletal muscle function with age, known as sarcopenia, significantly reduces independence and quality of life and can have significant metabolic consequences. Although exercise is effective in treating sarcopenia it is not always a viabl
Externí odkaz:
https://doaj.org/article/70070234940c48fc8d99e9a3f893e406
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0236430 (2020)
Rhesus macaques represent an important species for translational and pre-clinical research studies across a multitude of disease and injury models, including aging. Ketamine anesthesia is used in humans and non-human primates but may be associated wi
Externí odkaz:
https://doaj.org/article/82da4bd7630246ef84e7598c823fb96d
Autor:
Shinji Maegawa, Yue Lu, Tomomitsu Tahara, Justin T. Lee, Jozef Madzo, Shoudan Liang, Jaroslav Jelinek, Ricki J. Colman, Jean-Pierre J. Issa
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Caloric restriction has been shown to increase lifespan in mammals. Here, the authors provide evidence that age-related methylation drift correlates with lifespan and that caloric restriction in mice and rhesus monkeys results in attenuation of age-r
Externí odkaz:
https://doaj.org/article/7df8716f28e94df0a4d186d22d31c1a2
Autor:
Julie A. Mattison, Ricki J. Colman, T. Mark Beasley, David B. Allison, Joseph W. Kemnitz, George S. Roth, Donald K. Ingram, Richard Weindruch, Rafael de Cabo, Rozalyn M. Anderson
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Caloric restriction (CR) delays ageing of model organisms, but whether it works in nonhuman primates has been controversial. Here, the authors pool and reanalyse data from two long-running CR primate studies, concluding that moderate CR indeed improv
Externí odkaz:
https://doaj.org/article/3a76c66b68f7460284eef313ff046d21
Autor:
Michael A. Polewski, Maggie S. Burhans, Minghui Zhao, Ricki J. Colman, Dhanansayan Shanmuganayagam, Mary J. Lindstrom, James M. Ntambi, Rozalyn M. Anderson
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 8, Pp 1461-1470 (2015)
Metabolic syndrome is linked with obesity and is often first identified clinically by elevated BMI and elevated levels of fasting blood glucose that are generally secondary to insulin resistance. Using the highly translatable rhesus monkey (Macaca mu
Externí odkaz:
https://doaj.org/article/52f2e1a5b560458f924dac0acac42c4a
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0185695 (2017)
In the cooperative breeding common marmoset monkey, Callithrix jacchus, fathers share the care responsibility and energetic load with their mate from the time their infants are born. However, not all fathers show the same level of participation in di
Externí odkaz:
https://doaj.org/article/f0cdaf07d1a84169aa1a286d0b7ea7e1
Autor:
Marissa Kraynak, Molly M Willging, Alex L Kuehlmann, Amita A Kapoor, Matthew T Flowers, Ricki J Colman, Jon E Levine, David H Abbott
Publikováno v:
Journal of the Endocrine Society. 6
Context Ovarian estradiol supports female sexual behavior and metabolic function. While ovariectomy (OVX) in rodents abolishes sexual behavior and enables obesity, OVX in nonhuman primates decreases, but does not abolish, sexual behavior, and inconsi