Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Rickey R, Reinhardt"'
Autor:
Rickey R. Reinhardt, Thomas J. Povsic, Nahush A. Mokadam, Geoffrey A. Answini, Carl J. Pepine, Jay H. Traverse, Timothy D. Henry, Ronald G. Crystal, Howard C. Dittrich, Todd K. Rosengart, E. Magnus Ohman
Publikováno v:
American Heart Journal. 241:38-49
Background Patients with refractory angina (RA) have poor quality of life and new therapies are needed. XC001 is a novel adenoviral vector expressing multiple isoforms of vascular endothelial growth factor (VEGF) promoting an enhanced local angiogeni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2783c559aed7df6bee9707074cd74baa
https://doi.org/10.1016/j.ahj.2021.06.013
https://doi.org/10.1016/j.ahj.2021.06.013
Autor:
Jonathan Appleby, Francesca Ferrua, Katie Rolfe, Maria Grazia Roncarolo, Laura Castagnaro, Erika H. De Boever, Rickey R. Reinhardt, Maria Pia Cicalese, Alessandro Aiuti
Publikováno v:
Molecular Therapy
Loss of adenosine deaminase activity leads to severe combined immunodeficiency (ADA-SCID); production and function of T, B, and natural killer (NK) cells are impaired. Gene therapy (GT) with an autologous CD34+-enriched cell fraction that contains CD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa3e21bdc9dccc974bfea29f2545d4c6
http://europepmc.org/articles/PMC5910668
http://europepmc.org/articles/PMC5910668
Autor:
Jaime A. Davidson, Antonio Nino, Angela Jones-Leone, Timothy Wilson, Sergio Forero-Schwanhaeuser, Rickey R. Reinhardt
OBJECTIVE to evaluate the efficacy and safety of albiglutide compared with placebo and active comparators from an integrated trial subpopulation of Latino/Hispanic patients whose type 2 diabetes mellitus (T2DM) was inadequately controlled on their cu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b0b2c1e539ec8295e95a59ff7e3f7e3
Autor:
Rickey R. Reinhardt, Rebecca J. Hodge, Rhona Scott, Hui Zhi, Jessica E. Matthews, Malcolm A. Young, Jeffrey A. Wald
Publikováno v:
Postgraduate Medicine. 126:84-97
Albiglutide is a glucagon-like peptide-1 analogue composed of tandem copies of modified human glucagon-like peptide-1 (7-36) coupled to recombinant human albumin that is approved in adults for the treatment of type 2 diabetes mellitus. After subcutan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b343e6d153175e94a403fa7b6ce03740
https://doi.org/10.3810/pgm.2014.11.2836
https://doi.org/10.3810/pgm.2014.11.2836
Publikováno v:
Postgraduate Medicine. 126:35-46
Chronic kidney disease is frequently present in patients with type 2 diabetes mellitus (T2DM). New therapeutic options in this patient subpopulation are needed.Assess the effect of renal impairment on the pharmacokinetics (PK), efficacy, and safety o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c6e0aa8455bffa4433caf0b07d86683
https://doi.org/10.3810/pgm.2014.05.2754
https://doi.org/10.3810/pgm.2014.05.2754
Autor:
Hui Zhi, Jessica E. Matthews, Malcolm A. Young, Borje Darpo, Rickey R. Reinhardt, Meijian Zhou, Caroline R Perry
Publikováno v:
Diabetes Therapy
Introduction Albiglutide, a selective once-weekly glucagon-like peptide-1 receptor agonist, is being developed for the treatment of type 2 diabetes mellitus. Albiglutide’s effect on cardiac repolarization (QTc interval) was assessed in a randomized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fa2b7bcf743b7619f028c9797408bbf
http://europepmc.org/articles/PMC4065291
http://europepmc.org/articles/PMC4065291
Autor:
Polina Stepensky, Francesca Dionisio, Jennifer M. Puck, Maria Grazia Roncarolo, Katie Rolfe, Marco Bonopane, Ilhan Tezcan, Immacolata Brigida, Antonella Tabucchi, Robbert G. M. Bredius, Alessandro Aiuti, Eyal Grunebaum, Erika H. De Boever, Rickey R. Reinhardt, Miriam Casiraghi, Mehdi Adeli, Francesca Ferrua, Roberta Pajno, Federica Barzaghi, Jonathan Appleby, Maria Pia Cicalese, Fabio Ciceri, Laura Castagnaro, Filippo Carlucci, Stefania Giannelli
Publikováno v:
Blood, 128(1), 45-54
Adenosine deaminase (ADA) deficiency is a rare, autosomal-recessive systemic metabolic disease characterized by severe combined immunodeficiency (SCID). The treatment of choice for ADA-deficient SCID (ADA-SCID) is hematopoietic stem cell transplant f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81947c45c9b08f2e0d6a8925aef015ac
https://doi.org/10.1182/blood-2016-01-688226
https://doi.org/10.1182/blood-2016-01-688226
Publikováno v:
Postgraduate medicine. 128(4)
Glucagon-like peptide 1 receptor agonists (GLP-1 RAs) vary in their structure, duration of action, efficacy, and safety. In order to optimize glycemic control, it is important to target both fasting (FPG) and postprandial plasma (PPG) glucose. Althou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bae20b1fd33b372c75d26a5ec38826e5
https://pubmed.ncbi.nlm.nih.gov/27043162
https://pubmed.ncbi.nlm.nih.gov/27043162
Publikováno v:
The British Journal of Diabetes & Vascular Disease. 7:111-117
Obesity has reached epidemic proportions with an estimated 1.7 billion people worldwide classified as either overweight or obese. Obesity is associated with multiple co-morbidities (often clustered as the metabolic syndrome), and can result in decrea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ef8c07983663f8ce1a815acf12afbfd
https://doi.org/10.1177/14746514070070030301
https://doi.org/10.1177/14746514070070030301
Publikováno v:
Diabetes, obesitymetabolism. 18(9)
Gastrointestinal (GI) adverse events (AEs) are the most frequently reported treatment-related AEs associated with glucagon-like peptide-1 receptor agonists (GLP-1RAs) in the treatment of type 2 diabetes mellitus. The GI safety of albiglutide, a once-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7464982419bb907d26d43d0d108a78dc
https://pubmed.ncbi.nlm.nih.gov/27097971
https://pubmed.ncbi.nlm.nih.gov/27097971