Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Rick van der Geest"'
Autor:
Menno Hoekstra, Laura M. de Jong, Rick van der Geest, Lidewij R. de Leeuw, Rani Krisnamurthi, Janine J. Geerling, Miranda Van Eck
Publikováno v:
Biomolecules, Vol 14, Iss 4, p 429 (2024)
Preclinical studies regarding the potential of liver X receptor (LXR) agonists to inhibit macrophage foam cell formation and the development of atherosclerotic lesions are generally executed in mice fed with Western-type diets enriched in cholesterol
Externí odkaz:
https://doaj.org/article/81278c42970048989268f38ff1cfb5fb
Autor:
Rick van der Geest, Hongye Fan, Hernán F. Peñaloza, William G. Bain, Zeyu Xiong, Naina Kohli, Emily Larson, Mara L. G. Sullivan, Jonathan M. Franks, Donna B. Stolz, Ryota Ito, Kong Chen, Yohei Doi, Melanie J. Harriff, Janet S. Lee
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
IntroductionKlebsiella pneumoniae (Kp) is a common cause of hospital-acquired pneumonia. Although previous studies have suggested that evasion of phagocytic uptake is a virulence determinant of Kp, few studies have examined phagocytosis sensitivity i
Externí odkaz:
https://doaj.org/article/d52c265d2f874b8fa7c45a112a78d396
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The IL-36 family of cytokines were identified in the early 2000’s as a new subfamily of the IL-1 cytokine family, and since then, the role of IL-36 cytokines during various inflammatory processes has been characterized. While most of the research h
Externí odkaz:
https://doaj.org/article/7515a4e4023b479f9acd42feaa6c8494
Autor:
Hernán F. Peñaloza, Tolani F. Olonisakin, William G. Bain, Yanyan Qu, Rick van der Geest, Jill Zupetic, Mei Hulver, Zeyu Xiong, Michael W. Newstead, Chunbin Zou, Jonathan K. Alder, Joel A. Ybe, Theodore J. Standiford, Janet S. Lee
Publikováno v:
mBio, Vol 12, Iss 2 (2021)
Pseudomonas aeruginosa
Externí odkaz:
https://doaj.org/article/c3f646f87d284e3eadcfc706deab5378
Autor:
Sara R. Moore, Alison Morris, Bryan J. McVerry, Hui-Hua Li, Mehdi Nouraie, Mei Hulver, Rebecca S. DeSensi, Erin Papke, Yohei Doi, Georgios D Kitsios, Melissa Saul, William Bain, Rick van der Geest, Tolani F. Olonisakin, Prabir Ray, Rama K. Mallampalli, Viviana P. Ferreira, Yingze Zhang, Lina Ma, Brian Ahn, Sarah F. Rapport, Janet S. Lee, Hrishikesh S. Kulkarni, Zeyu Xiong, Kaveh Moghbeli
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 202:230-240
Rationale: Complement is crucial for host defense but may also drive dysregulated inflammation. There is limited understanding of alternative complement function, which can amplify all complement a...
Autor:
Tolani F. Olonisakin, Chunbin Zou, Mei Hulver, William Bain, Joel A. Ybe, Yanyan Qu, Jill Zupetic, Hernán F. Peñaloza, Michael W. Newstead, Jonathan K. Alder, Zeyu Xiong, Rick van der Geest, Janet S. Lee, Theodore J. Standiford
Publikováno v:
mBio, Vol 12, Iss 2 (2021)
mBio
mBio
Pseudomonas aeruginosa pulmonary infection can lead to exaggerated neutrophilic inflammation and tissue destruction, yet host factors that regulate the neutrophilic response is not fully known. IL-36γ is a proinflammatory cytokine that dramatically
Autor:
Amber B. Ouweneel, Joya E. Nahon, Janine J. Geerling, Ronald J. van der Sluis, Rick van der Geest, Juliet Price, Miranda Van Eck, Menno Hoekstra
Publikováno v:
Journal of Nutritional Biochemistry, 89, 108564
Scavenger receptor BI (SR-BI) has been suggested to modulate adipocyte function. To uncover the potential relevance of SR-BI for the development of obesity and associated metabolic complications, we compared the metabolic phenotype of wild-type and S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::747daeaa5f94a2da4da4f21475cbdc80
https://doi.org/10.1016/j.jnutbio.2020.108564
https://doi.org/10.1016/j.jnutbio.2020.108564
Autor:
Rick van der Geest, Alison Morris, Mara Sullivan, Mark A. Ross, Pamela J. Bjorkman, Mark S. Ladinsky, Georgios D Kitsios, Hernán F. Peñaloza, Bryan J. McVerry, Alan M. Watson, Claudette M. St. Croix, William Bain, Simon C. Watkins, Donna B. Stolz, Janet S. Lee, Barbara Methé
Publikováno v:
Chest
medRxiv
medRxiv
SARS-CoV-2 pneumonia may induce an aberrant immune response with brisk recruitment of myeloid cells into the lower respiratory tract, which may contribute to morbidity and mortality. We describe endotracheal aspirate samples from seven patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f11b90f8eaf02a0fff6aac0f3afc3789
Autor:
Daniel B. Kim-Shapiro, Mark T. Gladwin, Shekina Gonzalez-Ferrer, David O. Osei-Hwedieh, Samuel L. Brashears, Hernán F. Peñaloza, Tolani F. Olonisakin, Michael A. Bachman, Yuting Xiong, Claudette M. St. Croix, Valerian E. Kagan, Tomeka Suber, Prabir Ray, Andreas Perlegas, Zeyu Xiong, Janet S. Lee, Yulia Y. Tyurina, Eldad A. Hod, Jesús Tejero, Wendy M. Mars, Rick van der Geest, Anuradha Ray, Rama K. Mallampalli, Daria Van Tyne, Matthew R. Rosengart
Publikováno v:
J Clin Invest
Macrophages are main effectors of heme metabolism, increasing transiently in the liver during heightened disposal of damaged or senescent red blood cells (sRBC). Macrophages are also essential in defense against microbial threats, but pathologic stat
Autor:
Miranda Van Eck, Menno Hoekstra, Ronald J. van der Sluis, Albert K. Groen, Rick van der Geest
Publikováno v:
Journal of endocrinology, 242(2), 1-12. Society for Endocrinology
Journal of endocrinology, 242(2), 1-12. BIOSCIENTIFICA LTD
Journal of endocrinology, 242(2), 1-12. BIOSCIENTIFICA LTD
Chronic glucocorticoid overexposure predisposes to the development of atherosclerotic cardiovascular disease in humans. Cholestatic liver disease is associated with increased plasma glucocorticoid levels. Here, we determined – in a preclinical sett
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a980a77013f73a59e794dd1b36a51092
https://hdl.handle.net/1887/3198845
https://hdl.handle.net/1887/3198845