Zobrazeno 1 - 10
of 331
pro vyhledávání: '"Rick M. Maizels"'
Autor:
Graham A. Heieis, Thiago A. Patente, Luís Almeida, Frank Vrieling, Tamar Tak, Georgia Perona-Wright, Rick M. Maizels, Rinke Stienstra, Bart Everts
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-4 (2024)
Externí odkaz:
https://doaj.org/article/c1eb1019593e46af8b3269e42d2d92dc
Autor:
Graham A. Heieis, Thiago A. Patente, Luís Almeida, Frank Vrieling, Tamar Tak, Georgia Perona-Wright, Rick M. Maizels, Rinke Stienstra, Bart Everts
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Tissue-resident macrophage populations constitute a mosaic of phenotypes, yet how their metabolic states link to the range of phenotypes and functions in vivo is still poorly defined. Here, using high-dimensional spectral flow cytometry, we
Externí odkaz:
https://doaj.org/article/d17b85a99d2744e4a0b254d4b464b479
Publikováno v:
STAR Protocols, Vol 4, Iss 4, Pp 102608- (2023)
Summary: Parasitic helminth worms frequently infect the gastrointestinal tract and interact with the intestinal epithelium and specialized cell types within it. Intestinal organoids derived from stem cells that line the intestine represent a transfor
Externí odkaz:
https://doaj.org/article/3af02bea6fe145e2ae887bd29fdf4435
Autor:
Christopher J. Kelly, Susan L. Lindsay, Rebecca Sherrard Smith, Siew Keh, Kyle T. Cunningham, Katja Thümmler, Rick M. Maizels, John D. M. Campbell, Susan C. Barnett
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 743 (2024)
Demyelination in the central nervous system (CNS) resulting from injury or disease can cause loss of nerve function and paralysis. Cell therapies intended to promote remyelination of axons are a promising avenue of treatment, with mesenchymal stromal
Externí odkaz:
https://doaj.org/article/44c61ad8c0c742d49709078658397db6
Autor:
Marta Campillo Poveda, Collette Britton, Eileen Devaney, Tom N. McNeilly, François Gerbe, Philippe Jay, Rick M. Maizels
Publikováno v:
Cells, Vol 12, Iss 20, p 2477 (2023)
Tuft cells have recently emerged as the focus of intense interest following the discovery of their chemosensory role in the intestinal tract, and their ability to activate Type 2 immune responses to helminth parasites. Moreover, they populate a wide
Externí odkaz:
https://doaj.org/article/f2ce9a5d7d3244869ad7cd2cdbc490e9
Autor:
Ruby White, Javier Sotillo, María Eugenia Ancarola, Anne Borup, Anders Toftegaard Boysen, Paul J. Brindley, Edit I. Buzás, Serena Cavallero, Sujittra Chaiyadet, Iain W. Chalmers, Marcela A. Cucher, Maude Dagenais, Chelsea N. Davis, Eileen Devaney, Maria A. Duque‐Correa, Ramon Marc Eichenberger, Santiago Fontenla, Thomas A. Gasan, Cornelis H. Hokke, Maja Kosanovic, Marije E. Kuipers, Thewarach Laha, Alex Loukas, Rick M. Maizels, Antonio Marcilla, Hynek Mazanec, Russell M. Morphew, Kyriaki Neophytou, Linh Thuy Nguyen, Esther Nolte‐‘t Hoen, Michael Povelones, Mark W. Robinson, Alicia Rojas, Irma Schabussova, Hermelijn H. Smits, Sivapong Sungpradit, Lucienne Tritten, Bradley Whitehead, Amin Zakeri, Peter Nejsum, Amy H. Buck, Karl F. Hoffmann
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 1, Pp n/a-n/a (2023)
Abstract Over the last decade, research interest in defining how extracellular vesicles (EVs) shape cross‐species communication has grown rapidly. Parasitic helminths, worm species found in the phyla Nematoda and Platyhelminthes, are well‐recogni
Externí odkaz:
https://doaj.org/article/46a18460ff6e4def83a43ae02a7ed46f
Autor:
Bergithe E. Oftedal, Stefano Maio, Adam E. Handel, Madeleine P. J. White, Duncan Howie, Simon Davis, Nicolas Prevot, Ioanna A. Rota, Mary E. Deadman, Benedikt M. Kessler, Roman Fischer, Nikolaus S. Trede, Erdinc Sezgin, Rick M. Maizels, Georg A. Holländer
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Oftedal et al. generate mice lacking the chaperonin subunit CCT8 in T cells. They find that loss of CCT8 leads to reduced formation of nuclear actin filaments, changes in proteostasis, defective Th2 cell polarization and T cell metabolism and a faile
Externí odkaz:
https://doaj.org/article/f3b7f22ef77541f089085a26cdea4934
Autor:
Katie A. Hildersley, Tom N. McNeilly, Victoria Gillan, Thomas D. Otto, Stephan Löser, François Gerbe, Philippe Jay, Rick M. Maizels, Eileen Devaney, Collette Britton
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Helminth parasite infections of humans and livestock are a global health and economic problem. Resistance of helminths to current drug treatment is an increasing problem and alternative control approaches, including vaccines, are needed. Effective va
Externí odkaz:
https://doaj.org/article/3d47635cf36f42a0a19214acb01c4e0c
Autor:
Madeleine P. J. White, Chris J. C. Johnston, John R. Grainger, Joanne E. Konkel, Richard A. O'Connor, Stephen M. Anderton, Rick M. Maizels
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Helminth parasites are effective in biasing Th2 immunity and inducing regulatory pathways that minimize excessive inflammation within their hosts, thus allowing chronic infection to occur whilst also suppressing bystander atopic or autoimmune disease
Externí odkaz:
https://doaj.org/article/44678ea415b2410ba3cc2dbfdfecedc5
Autor:
Marion Rolot, Annette M. Dougall, Alisha Chetty, Justine Javaux, Ting Chen, Xue Xiao, Bénédicte Machiels, Murray E. Selkirk, Rick M. Maizels, Cornelis Hokke, Olivier Denis, Frank Brombacher, Alain Vanderplasschen, Laurent Gillet, William G. C. Horsnell, Benjamin G. Dewals
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Parasitic helminth infection is known to impact upon the host response to other bystander inflammatory processes. Here the authors show that IL4 production induced by helminth infection results in expansion of bystander CD8+ memory T cells and enhanc
Externí odkaz:
https://doaj.org/article/f3ad242413cc462394be270aad7af477