Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Rick L. Meek"'
Autor:
Brad P Dieter, Rick L Meek, Robert J Anderberg, Sheryl K Cooney, Jen L Bergin, Hongyu Zhang, Viji Nair, Matthias Kretzler, Frank C Brosius, Katherine R Tuttle
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0211555 (2019)
BackgroundSerum amyloid A (SAA), a potent inflammatory mediator, and Janus kinase 2 (JAK2), an intracellular signaling kinase, are increased by diabetes. The aims were to elucidate: 1) a JAK2-mediated pathway for increased SAA in the kidneys of diabe
Externí odkaz:
https://doaj.org/article/0821f4b6cda849aba7b4afc4d70f4719
Autor:
Hongyu Zhang, Katherine R. Tuttle, Rick L. Meek, Frank C. Brosius, Sheryl K. Cooney, Robert J. Anderberg, Brad P. Dieter, Jen L. Bergin, Matthias Kretzler, Viji Nair
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 2, p e0211555 (2019)
PLoS ONE, Vol 14, Iss 2, p e0211555 (2019)
BackgroundSerum amyloid A (SAA), a potent inflammatory mediator, and Janus kinase 2 (JAK2), an intracellular signaling kinase, are increased by diabetes. The aims were to elucidate: 1) a JAK2-mediated pathway for increased SAA in the kidneys of diabe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd6214b846484f599950a7e06257fe32
http://europepmc.org/articles/PMC6375550
http://europepmc.org/articles/PMC6375550
Autor:
Rajnish Mehrotra, Celestina Barbosa-Leiker, Katherine R. Tuttle, Ian H. de Boer, Maryam Afkarian, Brad P. Dieter, Robert Short, Rick L. Meek, Sterling McPherson, Radica Z. Alicic
Publikováno v:
Journal of Diabetes and its Complications. 30:1467-1472
Aims To determine if serum levels of serum amyloid A (SAA) predict death and end-stage renal disease in a cohort of people with diabetic kidney disease. Methods In a longitudinal cohort study of 135 participants with type 2 diabetes and diabetic kidn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2746c4b6cce336505afedd8265995c3
https://doi.org/10.1016/j.jdiacomp.2016.07.018
https://doi.org/10.1016/j.jdiacomp.2016.07.018
Autor:
Kelly L. Hudkins, Katherine R. Tuttle, Sheryl K. Cooney, Rick L. Meek, Renee C. LeBoeuf, Charles E. Alpers, Robert J. Anderberg
Publikováno v:
Laboratory Investigation; a Journal of Technical Methods and Pathology
Inflammatory pathways are central mechanisms in diabetic kidney disease (DKD). Serum amyloid A (SAA) is increased by chronic inflammation, but SAA has not been previously evaluated as a potential DKD mediator. The aims of this study were to determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b53612470e3d9ff5cfe9c8522619aab
http://europepmc.org/articles/PMC4346621
http://europepmc.org/articles/PMC4346621
Publikováno v:
American Journal of Nephrology. 29:171-180
Background/Aims: High levels of glucose and/or amino acids increase advanced glycation end products (AGE) and activate protein kinase C (PKC), a key signal for injury in mesangial cells. The aim was to determine whether oxidative stress mediates bidi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ba48158397092177df540fca627e9ab
https://doi.org/10.1159/000154470
https://doi.org/10.1159/000154470
Publikováno v:
Inflammation and Cell Signaling.
Inflammation contributes a significant part to the advancement of diabetic kidney disease (DKD), yet relatively little is known about the root cause of these inflammatory events. Serum Amyloid A (SAA) triggers a potent inflammatory response in a vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1db2fdf1d8797f0987a114b027814a30
https://doi.org/10.14800/ics.959
https://doi.org/10.14800/ics.959
Autor:
Katherine R. Tuttle, Brad P. Dieter, Rick L. Meek, Sheryl K. Cooney, Radica Z. Alicic, Robert J. Anderberg
Publikováno v:
Diabetes Spectrum : A Publication of the American Diabetes Association
IN BRIEF Current therapeutic approaches are only moderately efficacious at preventing the progression of diabetic kidney disease (DKD). As the number of people with DKD continues to rise worldwide, there is an urgent need for novel therapies. A bette
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7122ea09628485d3a6c0db02b09a31bc
https://pubmed.ncbi.nlm.nih.gov/26300609
https://pubmed.ncbi.nlm.nih.gov/26300609
Autor:
Joanne E. Murphy-Ullrich, Katherine R. Tuttle, Sheryl K. Cooney, Robert F. Chouinard, Maria H. Poczatek, Stephanie D. Flynn, Rick L. Meek
Publikováno v:
American Journal of Physiology-Renal Physiology. 285:F79-F86
High-protein diets exacerbate glomerular hyperfiltration and the progression of diabetic nephropathy. The purpose of this study was to determine whether amino acids also produce nonhemodynamic injury in the glomerulus. When rat mesangial cells were c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6596a1f74ef30f9476cf333515806ee
https://doi.org/10.1152/ajprenal.00419.2002
https://doi.org/10.1152/ajprenal.00419.2002
Autor:
William G. Couser, James A. Bassuk, Raimund Pichler, Richard J. Johnson, Kathy Gordon, Jeffrey Pippen, Justin D. Rothmier, Rick L. Meek, May J. Reed, Donna Lombardi, E. Helene Sage, Amy D. Bradshaw, Thomas P. Strandjord
Publikováno v:
Kidney International. 57:117-128
Induction of TGF-β1 by the matricellular protein SPARC in a rat model of glomerulonephritis.BackgroundSPARC has been implicated as a counteradhesive and antiproliferative protein associated with deposits of extracellular matrix in renal disease.Meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aec14be8a57835b1a46602984d654a0
https://doi.org/10.1046/j.1523-1755.2000.00811.x
https://doi.org/10.1046/j.1523-1755.2000.00811.x