Zobrazeno 1 - 10
of 379
pro vyhledávání: '"Rick G Schnellmann"'
Autor:
Ingrid L. Peterson, Erika Liktor-Busa, Kelly L. Karlage, Sally J. Young, Natalie E. Scholpa, Rick G. Schnellmann, Tally M. Largent-Milnes
Publikováno v:
The Journal of Headache and Pain, Vol 25, Iss 1, Pp 1-16 (2024)
Abstract Background Headache is a pain disorder present in populations world-wide with a higher incidence in females. Specifically, the incidences of medication overuse headache (MOH) have increased worldwide. Comorbidities of MOH include photosensit
Externí odkaz:
https://doaj.org/article/345ab5202f8f44128a0802ff54406905
Autor:
Danielle A. Becktel, Jennifer B. Frye, Elizabeth H. Le, Susan A. Whitman, Rick G. Schnellmann, Helena W. Morrison, Kristian P. Doyle
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 9, Pp 100614- (2024)
Ischemic stroke remains a leading cause of mortality and long-term disability worldwide, necessitating efforts to identify biomarkers for diagnosis, prognosis, and treatment monitoring. The present study aimed to identify novel plasma biomarkers of n
Externí odkaz:
https://doaj.org/article/feeba4deab6342fbba07121e68c902ff
Publikováno v:
Pharmacological Research, Vol 203, Iss , Pp 107154- (2024)
Serotonin, while conventionally recognized as a neurotransmitter in the CNS, has recently gained attention for its role in the kidney. Specifically, serotonin is not only synthesized in the kidney, but it also regulates glomerular function, vascular
Externí odkaz:
https://doaj.org/article/7bcf3ed1019c4fc086eb8ed280b883d1
Autor:
Natalie E. Scholpa, Epiphani C. Simmons, Austin D. Thompson, Seth S. Carroll, Rick G. Schnellmann
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
IntroductionVascular and mitochondrial dysfunction are well-established consequences of multiple central nervous system (CNS) disorders, including neurodegenerative diseases and traumatic injuries. We previously reported that 5-hydroxytryptamine 1F r
Externí odkaz:
https://doaj.org/article/93d51c5710234735afbb40e845c8aa8f
Autor:
Ingrid L. Peterson, Austin D. Thompson, Natalie E. Scholpa, Tally Largent-Milnes, Rick G. Schnellmann
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Astrocytes are a widely heterogenic cell population that play major roles in central nervous system (CNS) homeostasis and neurotransmission, as well as in various neuropathologies, including spinal cord injury (SCI), traumatic brain injury, and neuro
Externí odkaz:
https://doaj.org/article/307119ae89764f6e88893bb2dbc8740b
Autor:
Kevin A. Hurtado, Rick G. Schnellmann
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Background: Mitochondrial biogenesis (MB) induction through the activation of the 5-Hydroxytriptamine (5-HT) 1F receptor (HTR1F) is a promising mechanism for the treatment of diseases characterized by mitochondrial dysfunction, such as acute kidney i
Externí odkaz:
https://doaj.org/article/4be8f6eb54254227b38adbe1d6da98fd
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
During an episode of acute kidney injury (AKI), a sudden and rapid decline in renal function is often accompanied by a persistent reduction in mitochondrial function, microvasculature dysfunction/rarefaction, and tubular epithelial injury/necrosis. A
Externí odkaz:
https://doaj.org/article/0eeb98bfa7d84d66bc9386894790b4bf
Publikováno v:
American Journal of Physiology-Renal Physiology. 324:F56-F63
AKI pathology involves a rapid decline in kidney function and occurs in 8–16% of hospitalized patients. There is currently no therapeutic for AKI. AKI results in mitochondria dysfunction, microvasculature injury, and loss of renal tubular function.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c6efe5970cf88fe0a5dbe4686933bcf
https://doi.org/10.1152/ajprenal.00249.2022
https://doi.org/10.1152/ajprenal.00249.2022
Autor:
Hemendra J. Vekaria, W. Brad Hubbard, Natalie E. Scholpa, Malinda L. Spry, Jennifer L. Gooch, Sydney J. Prince, Rick G. Schnellmann, Patrick G. Sullivan
Publikováno v:
Neurobiology of Disease, Vol 140, Iss , Pp 104866- (2020)
Traumatic brain injury (TBI) leads to acute necrosis at the site of injury followed by a sequence of secondary events lasting from hours to weeks and often years. Targeting mitochondrial impairment following TBI has shown improvements in brain mitoch
Externí odkaz:
https://doaj.org/article/d6b090ab489f43e39ac740c82e4dd014
Publikováno v:
Pharmaceutics, Vol 14, Iss 3, p 638 (2022)
Polymeric nanoparticles’ drug delivery systems represent a promising platform for targeted controlled release since they are capable of improving the bioavailability and tissue localization of drugs compared to traditional means of administration.
Externí odkaz:
https://doaj.org/article/8fe6f3265b2a484890cdb15e23a30fb2