Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Rick D. Holly"'
Autor:
Cecile M Krejsa, Rick D Holly, Mark Heipel, Ken M Bannink, Rebecca Johnson, Richard Roque, Jane Heffernan, Julie Hill, Lay Chin, Felecia Wagener, Faith Shiota, Katherine Henderson, Pallavur V Sivakumar, Hong-Ping Ren, Fariba Barahmand-Pour, Don Foster, Chris Clegg, Wayne Kindsvogel, Rafael Ponce, Steven D Hughes, Kim Waggie
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67256 (2013)
Rituximab, a monoclonal antibody targeting CD20 on B cells, is currently used to treat many subtypes of B cell lymphomas. However, treatment is not curative and response rates are variable. Recombinant interleukin-21 (rIL-21) is a cytokine that enhan
Externí odkaz:
https://doaj.org/article/75eba1524ef24901bc6062fdb1f8b56a
Autor:
Don Foster, Mark D. Heipel, Theodore E. Whitmore, Stacey R. Dillon, Margaret D. Moore, Susan Bort, Jane A. Gross, Cindy A. Sprecher, Karen L. Madden, Philippa J. Webster, Fenella C. Raymond, Janet V. Johnston, Cameron S. Brandt, Andrew Nelson, Teresa Gilbert, Kevin Hambly, Mark F. Maurer, Darrell C. Conklin, Sara K. Schrader, Francis J. Grant, Rick D. Holly, Andrew Ching, Wenfeng Xu, Sherri Mudri, Kenneth Kaushansky, Faith Shiota, Scott R. Presnell, Lena Yao, Angie Hammond, Catherine Lofton-Day, Steve K. Burkhead, Julia Parrish-Novak, Chris Clegg, Joseph L. Kuijper, Jon Berry, Deborah L. Smith, Janet M. Kramer, James A. West
Publikováno v:
Nature. 408:57-63
Cytokines are important in the regulation of haematopoiesis and immune responses, and can influence lymphocyte development. Here we have identified a class I cytokine receptor that is selectively expressed in lymphoid tissues and is capable of signal
Publikováno v:
Biochemistry. 30:367-372
The human protein C precursor undergoes extensive co- and posttranslational modification during its biosynthesis in the liver. These modifications include glycosylation, gamma-carboxylation, and beta-hydroxylation of specific amino acids and endoprot
Autor:
Wayne R. Kindsvogel, Kim Waggie, Lay Chin, Felecia Wagener, Ken M. Bannink, Don Foster, Rick D. Holly, Pallavur Sivakumar, Julie Hill, Rafael Ponce, Rebecca Johnson, Richard Roque, Fariba Barahmand-pour, Steven D. Hughes, Hong-Ping Ren, Chris Clegg, Jane Heffernan, Faith Shiota, Cecile M. Krejsa, Mark Heipel, Katherine Henderson
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67256 (2013)
PLoS ONE
PLoS ONE
Rituximab, a monoclonal antibody targeting CD20 on B cells, is currently used to treat many subtypes of B cell lymphomas. However, treatment is not curative and response rates are variable. Recombinant interleukin-21 (rIL-21) is a cytokine that enhan
Autor:
Rick D. Holly, Donald C. Foster
Publikováno v:
Biochemistry. 33(7)
Human activated protein C (APC) has been shown to be physiologically susceptible to inhibition by the abundant serpin inhibitor alpha-1-anti-trypsin (AAT). Studies on the inactivation by AAT [Heeb, M. J., & Griffin, J. H. (1988) J. Biol. Chem. 263, 1
Autor:
Arvind Kumar, Rick D. Holly, Kathleen M. Walker, Cindy A. Sprecher, Donald C. Foster, Jay E. Gambee
Publikováno v:
Biochemistry. 29(2)
The human protein C precursor undergoes extensive co- and posttranslational modification during its biosynthesis in the liver. These modifications include glycosylation, gamma-carboxylation and beta-hydroxylation of specific amino acids, and endoprot
Autor:
Ken Bannink, Mark D. Heipel, Becky Johnson, Rick D. Holly, Wayne R. Kindsvogel, Steve D. Hughes, Don Foster, Cecile M. Krejsa, P.V. Sivakumar, Katherine E. Henderson, Eric Sievers, Chris Clegg
Publikováno v:
Blood. 104:1404-1404
Interleukin 21 (IL-21) is an IL-2 family cytokine produced by activated CD4+ T cells. Potent effects of IL-21 have been observed on the growth, survival, and functional activation of T cells, B cells, and natural killer (NK) cells. A Phase I clinical