Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Rick D Edmondson"'
Autor:
Sydnye L Shuttleworth, Aaron J Storey, Michael A Bauer, Jessica L Kelliher, Lora J Rogers, Daniel Fil, Rick D Edmondson, Sam G Mackintosh, Alan J Tackett, Brian Koss
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/9cb38792be9547f0b106a607b70915a1
Autor:
Tiffany N. Caza, Aaron J. Storey, Samar I. Hassen, Christian Herzog, Rick D. Edmondson, John M. Arthur, Daniel J. Kenan, Christopher P. Larsen
Publikováno v:
Kidney International. 103:593-606
Autor:
Dongxu Li, Xufen Yu, Jithesh Kottur, Weida Gong, Zhao Zhang, Aaron J. Storey, Yi-Hsuan Tsai, Hidetaka Uryu, Yudao Shen, Stephanie D. Byrum, Rick D. Edmondson, Samuel G. Mackintosh, Ling Cai, Zhijie Liu, Aneel K. Aggarwal, Alan J. Tackett, Jing Liu, Jian Jin, Gang Greg Wang
Publikováno v:
Oncogene
WD repeat domain 5 (WDR5), an integral component of the MLL/KMT2A lysine methyltransferase complex, is critically involved in oncogenesis and represents an attractive onco-target. Inhibitors targeting protein-protein interactions (PPIs) between WDR5
Autor:
Alan J. Tackett, Gang Greg Wang, Thomas F. Gajewski, Nukhet Aykin-Burns, Rick D. Edmondson, Samuel G. Mackintosh, Tung-Chin Chiang, Kimberly J. Krager, Jason B. Williams, Hidetaka Uryu, Jeong Hyun Ahn, Samrat Roy Choudhury, Charity L. Washam, Allen J. Gies, Stephanie D. Byrum, Aaron J. Storey, Erin M. Taylor, Bradley D. Shields, Brian Koss
T-cell exhaustion in cancer is linked to poor clinical outcomes, where evidence suggests T-cell metabolic changes precede functional exhaustion. Direct competition between tumor-infiltrating lymphocytes (TIL) and cancer cells for metabolic resources
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f2aed658cb8479aa41c12a11abbf7a0
https://doi.org/10.1158/0008-5472.c.6512143.v1
https://doi.org/10.1158/0008-5472.c.6512143.v1
Autor:
Alan J. Tackett, Gang Greg Wang, Thomas F. Gajewski, Nukhet Aykin-Burns, Rick D. Edmondson, Samuel G. Mackintosh, Tung-Chin Chiang, Kimberly J. Krager, Jason B. Williams, Hidetaka Uryu, Jeong Hyun Ahn, Samrat Roy Choudhury, Charity L. Washam, Allen J. Gies, Stephanie D. Byrum, Aaron J. Storey, Erin M. Taylor, Bradley D. Shields, Brian Koss
Figure S1-7. Figure S1: Assessing the effect of EZH2i on in vitro T cell cytotoxic function. Figure S2: Systems approach uncovers drivers of T cell exhaustion resulting from EZH2-inhibtion. Figure S3: Loss of EZH2 function leads to metabolic exhausti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7199995713bf285261746195a1b94520
https://doi.org/10.1158/0008-5472.22425820
https://doi.org/10.1158/0008-5472.22425820
Autor:
Jon B. Klein, Tiffany Caza, Issa Kawalit, Fred Clayton, Christian Herzog, Tim Cummins, Ronald Sjöberg, Brandi L Williams, Rick D. Edmondson, John M. Arthur, Michael L. Merchant, Monica P. Revelo, Jo Abraham, Tianxin Yang, Laith Al-Rabadi, Nicole K. Andeen, Nirupama Ramkumar, Laurence H. Beck, Aylin R. Rodan, Daniel W. Wilkey, Jeremy Chien, Chang Jiang Zou, Claire Trivin-Avillach, Willisa Liou, Edwin Lin, Christopher P. Larsen, Norifumi Hayashi, Aaron J. Storey
Publikováno v:
J Am Soc Nephrol
Background Identification of target antigens PLA2R, THSD7A, NELL1, or Semaphorin-3B can explain the majority of cases of primary membranous nephropathy (MN). However, target antigens remain unidentified in 15%-20% of patients. Methods A multipronged
Autor:
Michael Kuperman, Tiffany Caza, Aaron J. Storey, Zeljko Dvanajscak, Samar I. Hassen, Daniel J. Kenan, Shree G. Sharma, Rick D. Edmondson, John M. Arthur, Christopher P. Larsen, Christian Herzog
Publikováno v:
Kidney Int
Membranous lupus nephritis is a frequent cause of nephrotic syndrome in patients with systemic lupus erythematosus. It has been shown in phospholipase A2 receptor positive membranous nephropathy that known antibodies can be detected within sera, dete
Autor:
Jeong Hyun Ahn, Kimberly J. Krager, Allen Gies, Rick D. Edmondson, Jason B. Williams, Bradley D. Shields, Samuel G. Mackintosh, Tung-Chin Chiang, Stephanie D. Byrum, Hidetaka Uryu, Samrat Roy Choudhury, Alan J. Tackett, Charity L. Washam, Erin M. Taylor, Thomas F. Gajewski, Nukhet Aykin-Burns, Aaron J. Storey, Gang Greg Wang, Brian Koss
Publikováno v:
Cancer Research. 80:4707-4719
T-cell exhaustion in cancer is linked to poor clinical outcomes, where evidence suggests T-cell metabolic changes precede functional exhaustion. Direct competition between tumor-infiltrating lymphocytes (TIL) and cancer cells for metabolic resources
Autor:
Magdalena Foltman, Cecile Evrin, Giacomo De Piccoli, Richard C. Jones, Rick D. Edmondson, Yuki Katou, Ryuichiro Nakato, Katsuhiko Shirahige, Karim Labib
Publikováno v:
Cell Reports, Vol 3, Iss 3, Pp 892-904 (2013)
DNA unwinding at eukaryotic replication forks displaces parental histones, which must be redeposited onto nascent DNA in order to preserve chromatin structure. By screening systematically for replisome components that pick up histones released from c
Externí odkaz:
https://doaj.org/article/4b4f4cc7789e4b009e9983ada1d5177c
Autor:
Alan J. Tackett, Rick D. Edmondson, Charity L. Washam, Samuel G. Mackintosh, Mark S. Smeltzer, Aura M. Ramirez, Karen E. Beenken, Horace J. Spencer, Stephanie D. Byrum
Publikováno v:
ACS Infectious Diseases
We used a murine model of postsurgical osteomyelitis (OM) to evaluate the relative virulence of the Staphylococcus aureus strain LAC and five isogenic variants that differ in the functional status of saeRS and sarA relative to each other. LAC and a v