Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Rick B. Meeker"'
Autor:
Carli K. Opland, Miles R. Bryan, Braxton Harris, Jake McGillion-Moore, Xu Tian, Youjun Chen, Michelle S. Itano, Graham H. Diering, Rick B. Meeker, Todd J. Cohen
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106905- (2023)
Summary: Tau-mediated toxicity is associated with cognitive decline and Alzheimer’s disease (AD) progression. In particular, tau post-translational modifications (PTMs) are thought to generate aberrant tau species resulting in neuronal dysfunction.
Externí odkaz:
https://doaj.org/article/b7f1210596e04e69bf9b211b6c093c4c
Autor:
Irina Balan, Laure Aurelian, Kimberly S. Williams, Brian Campbell, Rick B. Meeker, A. Leslie Morrow
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
We recently discovered that (3α,5α)3-hydroxypregnan-20-one (allopregnanolone) inhibits pro-inflammatory toll-like receptor (TLR) activation and cytokine/chemokine production in mouse macrophage RAW264.7 cells. The present studies evaluate neuroster
Externí odkaz:
https://doaj.org/article/44ed84a4e3a84904b61c24de85fc33d0
Autor:
Douglas J. Hermes, Ian R. Jacobs, Megan C. Key, Alexis F. League, Barkha J. Yadav-Samudrala, Changqing Xu, Virginia D. McLane, Sara R. Nass, Wei Jiang, Rick B. Meeker, Bogna M. Ignatowska-Jankowska, Aron H. Lichtman, Zibo Li, Zhanhong Wu, Hong Yuan, Pamela E. Knapp, Kurt F. Hauser, Sylvia Fitting
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-26 (2020)
Abstract Background Human immunodeficiency virus type-1 (HIV-1) and opiates cause long-term inflammatory insult to the central nervous system (CNS) and worsen disease progression and HIV-1-related neuropathology. The combination of these proinflammat
Externí odkaz:
https://doaj.org/article/9e4741df53be4e07958134c87b308da3
Autor:
Connor M. Wander, Jui-Heng Tseng, Sheng Song, Heba A. Al Housseiny, Dalton S. Tart, Aditi Ajit, Yen-Yu Ian Shih, Rebecca Lobrovich, Juan Song, Rick B. Meeker, David J. Irwin, Todd J. Cohen
Publikováno v:
iScience, Vol 23, Iss 7, Pp 101255- (2020)
Summary: The microtubule-associated tau protein forms pathological inclusions that accumulate in an age-dependent manner in tauopathies including Alzheimer's disease (AD). Since age is the major risk factor for AD, we examined endogenous tau species
Externí odkaz:
https://doaj.org/article/4d3bd9a5d99a43c1a2f2a65407b70fe6
Autor:
Jui-Heng Tseng, Ling Xie, Sheng Song, Youmei Xie, Lauren Allen, Deepa Ajit, Jau-Shyong Hong, Xian Chen, Rick B. Meeker, Todd J. Cohen
Publikováno v:
Cell Reports, Vol 20, Iss 9, Pp 2169-2183 (2017)
The initiating events that promote tau mislocalization and pathology in Alzheimer’s disease (AD) are not well defined, partly because of the lack of endogenous models that recapitulate tau dysfunction. We exposed wild-type neurons to a neuroinflamm
Externí odkaz:
https://doaj.org/article/1665a8b11919450b82d0f39837a40b91
Autor:
Claudia J. Kennedy, Andrea E. Thomson, Emily H. Griffith, Jonathan Fogle, B. Duncan X. Lascelles, Rick B. Meeker, Barbara L. Sherman, Margaret E. Gruen
Publikováno v:
Viruses, Vol 10, Iss 7, p 353 (2018)
Environmental enrichment is critical for alleviating stress in laboratory felines. However, there is a paucity of information about suitable enrichment for cats. This study aimed to determine preferred enrichment options of individually-housed, castr
Externí odkaz:
https://doaj.org/article/a9337572bfcb42e49ba1b02190e24f4c
Autor:
Rick B. Meeker, Lola Hudson
Publikováno v:
Veterinary Sciences, Vol 4, Iss 1, p 14 (2017)
Feline Immunodeficiency virus (FIV), similar to its human analog human immunodeficiency virus (HIV), enters the central nervous system (CNS) soon after infection and establishes a protected viral reservoir. The ensuing inflammation and damage give ri
Externí odkaz:
https://doaj.org/article/e458e9419fc6467a812bf5d6fc6f1b10
Autor:
Thomas Lane, Vadim Makarov, Julie A. E. Nelson, Rick B. Meeker, Giuseppina Sanna, Olga Riabova, Elena Kazakova, Natalia Monakhova, Andrey Tsedilin, Fabio Urbina, Thane Jones, Ashley Suchy, Sean Ekins
Publikováno v:
Journal of Medicinal Chemistry. 66:6193-6217
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2de2716b5fc8243f868b16421806e17d
https://doi.org/10.1021/acs.jmedchem.2c02055
https://doi.org/10.1021/acs.jmedchem.2c02055
Publikováno v:
J Neuroimmune Pharmacol
Previous studies indicated that nerve growth factor (NGF) and proNGF differentially regulate the phenotype of macrophages and microglia via actions at tropomyosin receptor kinase A (TrkA) and p75 neurotrophin receptors (p75(NTR)), respectively. The a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::883ae4f22c508a98bc0eeff508fe31d7
https://doi.org/10.1007/s11481-021-10002-x
https://doi.org/10.1007/s11481-021-10002-x
Autor:
Baggio A Evangelista, Kathleen S. M. Reed, Aimee E Cruikshank, Ivana Y Quiroga, Rick B. Meeker, Douglas H. Phanstiel, Sarah S. Cohen, Jui-Heng Tseng, Hyejung Won, Joey V Ragusa, Todd J. Cohen, Marielle L Bond
Alzheimers disease (AD) is a progressive neurodegenerative disease that impacts nearly 400 million people worldwide. The accumulation of amyloid beta (A{beta}) in the brain has historically been associated with AD, and recent evidence suggests that n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12b2fdac644b4c357232219b7c821ebb
https://doi.org/10.1101/2021.09.14.460110
https://doi.org/10.1101/2021.09.14.460110
