Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Rick Avery Finch"'
Publikováno v:
Cancer Research. 66:4089-4094
Despite recent advances in treatment, breast cancer remains a serious health threat for women. Traditional chemotherapies are limited by a lack of specificity for tumor cells and the cell cycle dependence of many chemotherapeutic agents. Here we repo
Autor:
Toshinari Muramatsu, Linda K Johnson, Rick Avery Finch, Alan C. Sartorelli, Z. Ping Lin, Giuseppe Pizzorno, Janine J. Leffert, Dennis R. Johnson
Publikováno v:
Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics. 14:331-343
The impact of mouse multidrug resistance genes mdrla/b and mrpl on age-related differences in the toxicity and biodistribution of vincristine (VCR) was evaluated in wild-type, mrpl(-/-), mdrla/b(-/-), and combined mdrla/b(-/-), mrpl(-/-) weanling and
Autor:
Zhi Qing Ma, Diane Markesich, Buckley Kohlhauff, Wade Walke, Ny Qian, Brian Zambrowicz, Eric C. Buxton, Arthur T. Sands, K. H. Holt, Anupma Gupta, Joseph Shaw, Ramiro Ramirez-Solis, Yi Hu, Zheng Zheng Shi, Qichao Zhu, Peter Kipp, M. Newhouse, Christophe Person, E. R. Wann, Joel Edwards, Wenhu Huang, Nianhua Xu, Gwenn M. Hansen, Rick Avery Finch, T. Perry, Carl Johan Friddle, Alejandro Abuin, David Potter, Mary Jean Sparks, D. Tran, Jeff Schrick, Crystal Jaing, J. D. Wallace, Billie Key, Lizabeth J. Richter, K. A. Platt
Publikováno v:
Cold Spring Harbor Symposia on Quantitative Biology. 68:311-316
Autor:
Alan C. Sartorelli, Gwendalyn J. Randolph, William A. Muller, Dirk Jäger, Davide F. Robbiani, Rick Avery Finch
Publikováno v:
Cell. 103:757-768
Adaptive immune responses begin after antigen-bearing dendritic cells (DCs) traffic from peripheral tissues to lymph nodes. Here, we show that DC migration from skin to lymph nodes utilizes the leukotriene C(4) (LTC(4)) transporter multidrug resistan
Publikováno v:
Blood. 96:2262-2268
Previous studies have demonstrated that combinations of all-trans retinoic acid (ATRA) with either granulocyte-colony stimulating factor (G-CSF) or lithium chloride (LiCl) produced synergistic terminal differentiation of WEHI-3B myelomonocytic leukem
Publikováno v:
Biochemical Pharmacology. 58:557-562
Growing interest in the MRP (multidrug resistance protein) gene stems from its importance in multidrug resistance to chemotherapy, its possible use in gene therapy, and its relationship with the glutathione system. The recent generation of mrp gene k
Publikováno v:
Advances in Enzyme Regulation. 39:3-12
The enzyme RR catalyzes the conversion of ribonucleoside diphosphates to their deoxyribonucleotide counterparts. RR is critical for the generation of the cytosine, adenine, and guanine deoxyribonucleotide 5'-triphosphate building blocks of DNA, which
Autor:
Mark E. Bardgett, Rick Avery Finch, Abraham Z. Snyder, Alan C. Sartorelli, Julie L. Dahlheimer, Vallabhaneni V. Rao, David Piwnica-Worms
Publikováno v:
Proceedings of the National Academy of Sciences. 96:3900-3905
The blood–brain barrier and a blood–cerebrospinal-fluid (CSF) barrier function together to isolate the brain from circulating drugs, toxins, and xenobiotics. The blood–CSF drug-permeability barrier is localized to the epithelium of the choroid
Publikováno v:
Experimental Cell Research. 242:274-284
The WEHI-3B D+ leukemia is a near-diploid differentiation-competent cell line that undergoes myeloid differentiation in response to retinoic acid. WEHI-3B D- cells, derived from WEHI-3B D+ cells, are near tetraploid and not responsive to the differen
Publikováno v:
Molecular and Cellular Biochemistry. 146:171-178
Previous studies showed that localization of nucleophosmin/B23 (NPM) to nucleoli requires adequate cellular GTP levels (Finch et al., J Biol Chem 268, 5823-5827, 1993). In order to study whether hydrolysis of GTP plays a role in NPM localization, we