Výsledky vyhledávání

A Randomized Trial of the Activity and Safety of Ro 24-7429 (Tat Antagonist) versus Nucleoside for Human Immunodeficiency Virus Infection

Autor: Richard Haubrich, Paul S. Lietman, Carla P. Pettinelli, Martin S. Hirsch, Richman Dd, Richard S. Ginsberg, Stephen A. Spector, Michael M. Lederman, Charles Flexner, Fayez M. Hamzeh

Publikováno v: Journal of Infectious Diseases. 172:1246-1252

Ro 24-7429, a Tat antagonist, dosed at 75, 150, or 300 mg/day, was compared with nucleoside analogue (zidovudine or didanosine) for 12 weeks in 96 human immunodeficiency virus (HIV)-infected patients to assess safety and activity. The primary adverse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2fc044355f889f344caea232c88d7a67
https://doi.org/10.1093/infdis/172.5.1246

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Impact of Pneumocystis carinii and Cytomegalovirus on the Course and Outcome of Atypical Pneumonia in Advanced Human Immunodeficiency Virus Disease

Autor: Angie E. Bartok, Stephen A. Spector, Richman Dd, Samuel A. Bozzette, McCutchan Ja, Arcia J, Lawrence M. McGlynn

Publikováno v: Journal of Infectious Diseases. 165:93-98

Patients undergoing bronchoscopy for possible pneumocystis pneumonia were studied retrospectively to characterize the impact of common viral pathogens on the course of advanced human immunodeficiency virus (HIV) disease and atypical pneumonia. In 327

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7838242dc65c8f7044360bf1d4e5379
https://doi.org/10.1093/infdis/165.1.93

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Resting cerebral blood flow: a potential biomarker of the effects of HIV in the brain

Autor: Ances, BM, Sisti, D, Vaida, F, Liang, CL, Leontiev, O, Perthen, JE, Buxton, RB, Benson, D, Smith, DM, Little, SJ, Richman, DD, Moore, DJ, Ellis, RJ, HNRC group

Publikováno v: Neurology, vol 73, iss 9

ObjectiveHIV enters the brain soon after infection causing neuronal damage and microglial/astrocyte dysfunction leading to neuropsychological impairment. We examined the impact of HIV on resting cerebral blood flow (rCBF) within the lenticular nuclei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3c7cd5cd300406c3d7b73aab752a1a89
https://escholarship.org/uc/item/20812252

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Viral dynamics of acute HIV-1 infection

Autor: Little, SJ, McLean, AR, Spina, CA, Richman, DD, Havlir, DV

Publikováno v: The Journal of experimental medicine, vol 190, iss 6

Viral dynamics were intensively investigated in eight patients with acute HIV infection to define the earliest rates of change in plasma HIV RNA before and after the start of antiretroviral therapy. We report the first estimates of the basic reproduc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::bbb338cb696520069d186acddc9c6c65
https://escholarship.org/uc/item/7p48c9nj

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A cross-sectional comparison of persons with syncytium- and non-syncytium-inducing human immunodeficiency virus

Autor: Stephen A. Spector, Brian Wright, Richman Dd, Samuel A. Bozzette, McCutchan Ja

Publikováno v: The Journal of infectious diseases. 168(6)

The association between isolation of the syncytium-inducing (SI) phenotype of human immunodeficiency virus (HIV) and unfavorable clinical and immune status was evaluated in a cross-sectional study. Data on HIV phenotype were available for 341 of 878

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c52058aa0a35e91227e950d1a92e6ff9
https://pubmed.ncbi.nlm.nih.gov/7930703

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Incidence of AIDS dementia in a two-year follow-up of AIDS and ARC patients on an initial phase II AZT placebo-controlled study: San Diego cohort

Autor: Day Jj, Robert K. Heaton, Joseph H. Atkinson, Richman Dd, McCutchan Ja, James D. Weinrich, Hesselink, Igor Grant, Stephen A. Spector, Lucy T. Brysk

Publikováno v: The Journal of neuropsychiatry and clinical neurosciences. 4(1)

In a prospective study to determine the incidence of clinical dementia in patients with AIDS and ARC, 29 men and 3 women, 19 with ARC and 13 with AIDS, were examined neurologically and neuropsychologically every 6 months for 2 years during a placebo-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0a510571903033699c1d8fc0762b200
https://pubmed.ncbi.nlm.nih.gov/1627957

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