Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Richelle DeBlasio"'
Autor:
Ornella Pagliano, Robert M. Morrison, Joe-Marc Chauvin, Hridesh Banerjee, Diwakar Davar, Quanquan Ding, Tokiyoshi Tanegashima, Wentao Gao, Saranya R. Chakka, Richelle DeBlasio, Ava Lowin, Kevin Kara, Mignane Ka, Bochra Zidi, Rada Amin, Itay Raphael, Shuowen Zhang, Simon C. Watkins, Cindy Sander, John M. Kirkwood, Marcus Bosenberg, Ana C. Anderson, Vijay K. Kuchroo, Lawrence P. Kane, Alan J. Korman, Arvind Rajpal, Sean M. West, Minhua Han, Christine Bee, Xiaodi Deng, Xiao Min Schebye, Pavel Strop, Hassane M. Zarour
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 9 (2022)
T cell immunoglobulin mucin domain-containing protein 3 (Tim-3) negatively regulates innate and adaptive immunity in cancer. To identify the mechanisms of Tim-3 in cancer immunity, we evaluated the effects of Tim-3 blockade in human and mouse melanom
Externí odkaz:
https://doaj.org/article/00341078d5a94f57ba93043742d00efb
Autor:
Hassane Zarour, John Kirkwood, Joe-Marc Chauvin, Arivarasan Karunamurthy, Douglas Hartman, Richelle DeBlasio, Quanquan Ding, Ornella Pagliano, Amy Rose
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/23cceed6d50e4d5b9102fa53543f2387
Publikováno v:
INNOVATIONS in Pharmacy, Vol 8, Iss 2 (2017)
Sexual and reproductive health is a critical focus area for adolescents and young adults (AYAs). Of the 20 million newly diagnosed Sexually Transmitted Infections (STIs) annually, nearly half of them are contracted by young people between the ages of
Externí odkaz:
https://doaj.org/article/8d18409263ff44f6b2e6b3ad62b7618a
Autor:
Hassane M. Zarour, Mark J. Smyth, Alan J. Korman, Robert J. Johnston, John M. Kirkwood, Diwakar Davar, Soldano Ferrone, Xian-Yang Li, Jiajie Hou, Cindy Sanders, Richelle DeBlasio, Quanquan Ding, Carmine Menna, Ornella Pagliano, Mignane Ka, Joe-Marc Chauvin
Purpose:Natural killer (NK) cells play a critical role in tumor immunosurveillance. Multiple activating and inhibitory receptors (IR) regulate NK-cell–mediated tumor control. The IR T-cell immunoglobulin and ITIM domain (TIGIT) and its counter-rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3868ce46eb0c84b21578b0324b54b3e
https://doi.org/10.1158/1078-0432.c.6529316.v1
https://doi.org/10.1158/1078-0432.c.6529316.v1
Autor:
Hassane M. Zarour, Mark J. Smyth, Alan J. Korman, Robert J. Johnston, John M. Kirkwood, Diwakar Davar, Soldano Ferrone, Xian-Yang Li, Jiajie Hou, Cindy Sanders, Richelle DeBlasio, Quanquan Ding, Carmine Menna, Ornella Pagliano, Mignane Ka, Joe-Marc Chauvin
Supplemental Figure 2. CD155 expression in melanoma cells inversely correlates with the TIGIT/CD226 expression ratio in TiNKs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ee8212e5728ae8a06bead24ea34fea5
https://doi.org/10.1158/1078-0432.22476167
https://doi.org/10.1158/1078-0432.22476167
Autor:
Diwakar Davar, Arivarasan Karunamurthy, Joe-Marc Chauvin, Robert Morrison, Yulong Bai, Jie Sun, Julie Stein, Richard Rodrigues, John McCulloch, Hong Wang, Douglas Hartman, Miriam Fernandes, Alicia Cole, Amiran Dzutsev, Christopher Deitrick, Riyue Bao, Umamaheswar Duvvuri, Shaum Sridha, Seungwon Kim, M. Haroon Choudry, Matthew Holtzman, James Pingpank, James O'Toole, Richelle DeBlasio, Yang Jin, Quanquan Ding, Wentao Gao, Christopher Groetsch, Ornella Pagliano, Amy Rose, Corey Urban, Jagjit Singh, Prajan Divakar, David Mauro, Dmitri Bobilev, James Wooldridge, Arthur Krieg, Matthew Fury, Yana Najjar, Jason Luke, John Kirkwood, Janis Taube, Hyun Jung Park, Giorgio Trinchieri, Hassane Zarour
Intratumoral TLR9 agonists and anti-PD-1 provide durable clinical responses and broad immune activation. To evaluate efficacy and mechanisms of action of this combined treatment, we conducted a single-arm phase 2 neoadjuvant study of TLR9 agonist vid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96fa939bdab81718d5fc7c5cbad18f8b
https://doi.org/10.21203/rs.3.rs-2235839/v1
https://doi.org/10.21203/rs.3.rs-2235839/v1
Autor:
Richelle DeBlasio, Marie Vétizou, Jonathan H. Badger, Giorgio Trinchieri, Stephanie Prescott, Hassane M. Zarour, Miriam R. Fernandes, John A. McCulloch, Bochra Zidi, Richard R. Rodrigues, Amir A. Borhani, Yana G. Najjar, Amy Rose, John M. Kirkwood, Shuowen Zhang, Hong Wang, Carmine Menna, Quanquan Ding, Scarlett J. Ernst, Amiran K. Dzutsev, Alicia M. Cole, Joe Marc Chauvin, Robert M. Morrison, Ornella Pagliano, Diwakar Davar, Andrey Morgun, Ascharya K. Balaji, Raquel Galvão Figueredo Costa, Howard M. Dubner, Ivan Vujkovic-Cvijin, Yasmine Belkaid, Marc Schwartz
Publikováno v:
Science. 371:595-602
New fecal microbiota for cancer patients The composition of the gut microbiome influences the response of cancer patients to immunotherapies. Baruch et al. and Davar et al. report first-in-human clinical trials to test whether fecal microbiota transp
Autor:
Hassane M. Zarour, Joe-Marc Chauvin, Richelle DeBlasio, Diwakar Davar, Ornella Pagliano, Douglas J. Hartman, Arivarasan Karunamurthy, Amy Rose, John M. Kirkwood, Quanquan Ding
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Neoadjuvant PD-1 blockade produces major pathological responses (MPR) in ~30% of patients (pts) with high-risk resectable melanoma (MEL) with durable relapse-free benefit, and increased circulating activated CD8+ T cells.1 2 CMP-001 is a t
Autor:
Jiajie Hou, Alan J. Korman, Xian-Yang Li, Joe-Marc Chauvin, Diwakar Davar, Ornella Pagliano, Mark J. Smyth, John M. Kirkwood, Mignane B. Ka, Richelle DeBlasio, Quanquan Ding, Robert J. Johnston, Hassane M. Zarour, Cindy Sanders, Soldano Ferrone, Carmine Menna
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 26(20)
Purpose: Natural killer (NK) cells play a critical role in tumor immunosurveillance. Multiple activating and inhibitory receptors (IR) regulate NK-cell–mediated tumor control. The IR T-cell immunoglobulin and ITIM domain (TIGIT) and its counter-rec
Autor:
Hassane M. Zarour, Richelle DeBlasio, Marc Schwartz, Stephanie Prescott, Ivan Vujkovic-Cvijin, Amy Rose, Marie Vétizou, Scarlett J. Ernst, Jonathan H. Badger, Howard M. Dubner, Hong Wang, Yasmine Belkaid, John M. Kirkwood, Ascharya K. Balaji, Amiran Dzutsev, Diwakar Davar, Yana G. Najjar, Quanquan Ding, Raquel Galvão Figueredo Costa, Joe-Marc Chauvin, Shuowen Zhang, Carmine Menna, Amir A. Borhani, Giorgio Trinchieri, John A. McCulloch, Bochra Zidi, Richard R. Rodrigues, Ornella Pagliano, Miriam R. Fernandes, Andrey Morgun, Robert M. Morrison, Alicia M. Cole
Publikováno v:
Cancer Research. 81:LB062-LB062
Background: Monoclonal antibodies (mAb) targeting the programmed cell death protein 1 (PD-1) receptor provide durable long-term benefit in a subset of patients (pts) with advanced melanoma with response rates of 35-42% and 4-year progression-free sur